Testing a drug for muscle loss in dialysis patients
Treatments studied
Part of Blood & lymphatic, Brain & nervous system clinical trials.
This trial tests whether a drug called roxadustat can help treat muscle loss (sarcopenia) in people on hemodialysis. It aims to see if improving anemia also strengthens muscles.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You have end-stage kidney disease and have been on hemodialysis for at least 16 weeks.
- Your hemoglobin levels have been between 7.0 and 10.0 g/dL in your last two checks.
- You have not used or have stopped taking erythropoiesis-stimulating agents or roxadustat.
- You have an internal fistula or long-term dialysis catheter.
- Your weight is between 45 and 100 kg.
- You have been diagnosed with sarcopenia: low grip strength and low muscle mass as measured by a body composition test.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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