Clin2
NCT07227246Possibly a fitRecruiting

Testing rFVIIa for bleeding stroke within 2 hours

Intracerebral Hemorrhage

Part of Brain & nervous system, Heart & circulation clinical trials.

This trial tests whether a drug called Recombinant Factor VIIa (rFVIIa) can safely help stop bleeding in the brain during a hemorrhagic stroke. The goal is to give the drug as quickly as possible, within 2 hours of stroke onset, to see if it improves outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
350 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You are between 18 and 80 years old.
  • You have a type of stroke called spontaneous intracerebral hemorrhage (bleeding in the brain) not caused by injury or other known conditions.
  • You can get the study drug within 2 hours of your stroke starting (or 1.5 hours if a certain sign on CT is absent).
  • You have not taken blood thinners (like warfarin or newer oral anticoagulants) within the last week.
  • You have no major disability before the stroke, no recent blood clots or heart problems, and are not pregnant or breastfeeding.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT03907046Recruiting· Phase 3
Blood thinner study to prevent stroke after brain bleed

This Phase 3 study tests whether a blood thinner (apixaban) can help prevent another stroke and support recovery after you’ve had a brain bleed. You would be assigned to a treatment group, and the study checks safety and whether strokes can be reduced without causing dangerous bleeding.

Birmingham, Alabama
NCT06899464Not yet recruiting· Phase 4
Testing cerebrolysin for brain bleeding

This trial tests whether a drug called cerebrolysin can help people who have a bleeding stroke in the outer part of the brain (lobar hemorrhage). It looks at safety and how well it works.

NCT05460793Recruiting
Surgery timing trial for brain bleeding after a stroke

This trial looks at whether starting brain surgery within 8 hours after a type of stroke called intracerebral hemorrhage (bleeding in the brain) can improve outcomes. It’s for adults with a certain amount and location of bleeding and without common causes like an aneurysm or malformation.

Amsterdam
NCT06696131Not yet recruiting· Phase 1
Testing tenecteplase for brain bleeding

This trial tests a clot-busting drug called tenecteplase to see if it can safely treat a large brain bleed (intracerebral hemorrhage). It may help people who had a bleed within the last 24 hours and whose CT scans show the bleed has stopped growing.

NCT07365150Recruiting
Tranexamic acid for brain bleeding

This study tests whether the drug tranexamic acid can help stop bleeding in the brain when given early. It is for people with a spontaneous brain bleed who are awake and can be treated within 6 hours.

Hong Kong
NCT07411079Recruiting
Testing clot-busting drug on brain bleed blood samples

This study collects blood samples from people with and without bleeding risk to test a clot-dissolving drug (tPA) outside the body. It aims to improve minimally invasive surgery for brain hemorrhages.

Lille

Hear when a new Intracerebral Hemorrhage trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.