Mild cooling during heart bypass surgery for brain protection
Part of Brain & nervous system, Heart & circulation, Injuries & trauma clinical trials.
This study compares two ways of keeping your body temperature during heart surgery to see which one helps protect your brain. Half of the patients will be cooled slightly (mild hypothermia), and half will be kept at normal temperature, to see if cooling reduces the risk of brain injury.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are scheduled for coronary artery bypass surgery (a heart operation to improve blood flow).
- Your surgery is planned in advance (not an emergency).
- You have never had a stroke, a mini-stroke, or bleeding in the brain.
- You do not have a brain condition such as Alzheimer's or multiple sclerosis.
- You have no metal implants that are not MRI-safe
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies whether different circulatory support techniques during coronary artery bypass surgery affect blood flow to the brain. It may help find ways to protect brain function during the procedure.
This trial compares two cooling temperatures during an “aortic hemiarch” operation to see which approach is safer and better for brain protection. It may help guide surgeons on the best cooling strategy for some planned heart surgeries.
This trial studies whether tailoring anesthesia and monitoring the brain’s blood-flow control during heart surgery can improve neurological outcomes (brain-related function and recovery). It may help by guiding anesthesia in a more individualized way and checking how well the brain is protected during the operation.
This study looks at the best body temperature to use during heart surgery when a heart-lung machine is needed. You may be able to join if you are having bypass surgery or valve repair, your risk score is moderate or higher, and your surgery is not an emergency.
This study tests a new way to monitor blood flow to the brain during heart surgery. The goal is to see if this can help protect the brain and reduce thinking problems after surgery.
This study tests whether cooling the heart with a cold liquid during a procedure (angioplasty) can help reduce damage after a heart attack. It may be an option for people who arrive at the hospital quickly after a heart attack.
Hear when a new Coronary artery disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.