Testing edoxaban for stroke prevention in older adults
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests if adding the blood thinner edoxaban to standard aspirin or clopidogrel therapy can better prevent another stroke in adults aged 75 and older who had a recent ischemic stroke and are in normal heart rhythm.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 75 years or older.
- You had a stroke (or a mini-stroke with brain changes on scans) in the last 12 months.
- You currently take aspirin 81 mg or clopidogrel 75 mg daily, not both.
- Your heart rhythm was monitored for at least 24 hours after your stroke with no sign of atrial fibrillation lasting 6 minutes or more.
- You do not have a condition requiring blood thinners other than aspirin or clopidogrel.
- You have no recent serious bleeding or high risk of bleeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if a lower dose of the blood thinner edoxaban can safely prevent another stroke in very elderly patients (80+) who have both atrial fibrillation and a past stroke or mini-stroke. It focuses on those with extra bleeding risks due to low weight, reduced kidney function, previous bleeds, or certain other medications.
This trial is testing two blood thinners (edoxaban and apixaban) to see how they compare in preventing new brain spots on MRI after a stroke in people with atrial fibrillation. It may help you and your doctor choose the safer option.
This study compares two types of blood-thinning medicines to see which one is better at preventing another stroke in people who had a stroke without a clear cause. It may help if you had a stroke recently and have certain heart-related risk factors.
This trial tests if starting blood thinners can prevent another stroke in people who had a stroke but were found to have a hidden heart rhythm problem called atrial fibrillation. It is for older adults who have had a recent stroke without a known cause.
This trial tests whether taking apixaban alone is as safe and effective as taking apixaban plus clopidogrel for people who have had a stroke due to atrial fibrillation and also have hardened arteries in the brain or neck. It aims to find the best way to prevent another stroke.
This trial tests a combination of two blood thinners (antiplatelet drugs) to see if they work better than one in people who had a mild stroke caused by a narrowed artery in the brain. If you had a recent first stroke and are otherwise healthy, you may be able to join.
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