Blood pressure drugs and lung function in acute respiratory failure
Treatments studied
Part of Heart & circulation clinical trials.
This study tests whether two blood pressure medications (nicardipine and nitroglycerin) affect how well your lungs exchange oxygen and remove carbon dioxide. It uses a special chest monitor to see if these drugs improve lung function during breathing machine support.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have acute respiratory failure (your blood oxygen level is low) and need a breathing machine.
- You are receiving blood pressure medication through an IV to keep your blood pressure stable.
- You do not have a pacemaker, defibrillator, or other metal device in your chest.
- You are not severely obese (BMI under 50) and do not have massive swelling under the skin.
- You are not pregnant or breastfeeding, and you are not taking certain erectile dysfunction drugs like Viagra or Cialis.
- You do not have conditions that make nitroglycerin unsafe, like severe anemia or increased pressure in the brain.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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