Study of a new drug for adults with low parathyroid hormone
Part of Hormones & metabolism clinical trials.
This trial tests an experimental drug called Canvuparatide against a placebo to see if it can help adults with a condition called hypoparathyroidism, where the body doesn't make enough parathyroid hormone. The goal is to improve calcium levels and reduce the need for high-dose calcium and vitamin D supplements.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have had hypoparathyroidism for at least 12 months, either after thyroid surgery or from other causes like genetics or autoimmune disease.
- You are currently taking at least 0.5 micrograms of calcitriol (a form of vitamin D) or 1.0 micrograms of alfacalcidol each day, plus at least 1000 milligrams of calcium (from supplements) for the past 12 weeks, with stable doses for the last 3 weeks.
- Your blood calcium level (adjusted for protein) has been between 7.8 and 9.4 mg/dL on two tests taken at least one week apart.
- You have not used any other parathyroid hormone drugs (like PTH 1-84 or 1-34) in the last 5 weeks.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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