Clinical trials
Hypoparathyroidism clinical trials
Below are recruiting hypoparathyroidism clinical trials, each written for real people, not researchers. We’re tracking 27 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07491601Recruiting
Preventing low parathyroid after thyroid surgery
This study aims to find ways to detect and prevent low parathyroid function after thyroid surgery. If you are having your whole thyroid removed, joining could help researchers learn how to improve recovery.
Würzburg, BavariaAges 18 years+ - NCT06961071RecruitingPhase 1/Phase 2
Parathyroid transplant for low parathyroid hormone
This trial tests whether a donated parathyroid gland can help people with low parathyroid hormone (hypoparathyroidism) control their calcium levels and reduce symptoms. Participants will receive transplant and short-term immune-suppressing drugs.
San Francisco, CaliforniaAges 18 years+ - NCT06645899Recruiting
Italian database for parathyroid conditions
This study is creating a database of people with hypoparathyroidism or pseudohypoparathyroidism in Italy. It may help researchers learn more about these conditions and improve future care.
AlessandriaAges Any age - NCT07081997RecruitingPhase 3
Higher-dose palopegteriparatide for hypoparathyroidism
This trial is for adults with hypoparathyroidism who are already taking a drug called palopegteriparatide (TransCon PTH) at a certain dose. It tests whether higher doses of this drug can better control calcium levels and reduce the need for other supplements.
Reno, NevadaAges 18 years+ - NCT03249012Recruiting
Quality of life after thyroid surgery for low calcium
This study looks at how different treatment plans affect quality of life in people who develop low calcium after thyroid surgery. You may be asked to complete questionnaires to compare how you feel with each treatment approach.
Québec, QuebecAges 18 years+ - NCT07577570Recruiting
Calcium Treatment After Thyroid Surgery
This study tests whether calcium supplements help patients whose parathyroid glands aren't working properly after thyroid surgery. The parathyroid glands control calcium levels in your body, and they can be accidentally injured during thyroid removal.
Tallinn, OtherAges 18 years+ - NCT06499246Recruiting
Parathyroid transplant for severe low calcium after thyroid removal
This trial tests a parathyroid gland transplant for people with severe, long-term low calcium levels after thyroid removal. It aims to help those who still have symptoms despite high-dose calcium and vitamin D supplements.
Toronto, OntarioAges 19 years+ - NCT07706764RecruitingPhase 3
Testing a new treatment for teens with long-term hypoparathyroidism
This study tests a new medicine called palopegteriparatide for teenagers with long-term hypoparathyroidism (low parathyroid hormone). The medicine is given as a daily injection and aims to help control calcium levels.
BronAges 12–18 - NCT07699471RecruitingPhase 3
Study of a new drug for adults with low parathyroid hormone
This trial tests an experimental drug called Canvuparatide against a placebo to see if it can help adults with a condition called hypoparathyroidism, where the body doesn't make enough parathyroid hormone. The goal is to improve calcium levels and reduce the need for high-dose calcium and vitamin D supplements.
Homestead, FloridaAges 18 years+ - NCT05793853Recruiting
Study of how hypoparathyroidism changes over time
This study follows adults with hypoparathyroidism to better understand what symptoms and lab levels change over time. It may help doctors plan future treatments by learning the natural course of the condition, even if you already take standard medicines.
New York, New YorkAges 18–100 - NCT06988670RecruitingPhase 2
Testing EXT608 for adults with hypoparathyroidism
This trial tests a new medicine called EXT608 for adults with hypoparathyroidism. It aims to see if this medicine can help manage calcium levels better than current treatments.
Buenos Aires, Buenos Aires F.D.Ages 18–65 - NCT07034677RecruitingPhase 4
Study of indapamide for low calcium after thyroid surgery
This trial tests if a blood pressure medication called indapamide can help people who have low calcium levels after having their thyroid (or parathyroid) glands removed. It may help reduce the need for high doses of vitamin D.
AarhusAges 18 years+ - NCT07197450RecruitingEarly Phase 1
Study of XH02 for hypoparathyroidism
This trial tests an investigational drug called XH02 for people with hypoparathyroidism (low parathyroid hormone) that is not well controlled with standard calcium and vitamin D treatments. The goal is to see if XH02 is safe and effective at managing symptoms.
BeijingAges 18–65 - NCT02838927Recruiting
Registry study of chronic low parathyroid function in France
This is a registry (data collection) study that gathers information about people diagnosed with chronic hypoparathyroidism in France. It helps researchers better understand how common it is and what it looks like in real life.
Saint-Denis, La RéunionAges Any age - NCT07530705RecruitingPhase 1/Phase 2
XH-02 Injection for Low Parathyroid Hormone Levels
This study tests whether a new injectable medicine called XH-02 can safely treat hypoparathyroidism—a condition where your body doesn't make enough parathyroid hormone, causing low calcium levels. If your calcium isn't well-controlled with current treatments (calcium and vitamin D supplements), this trial might help.
Beijing, Beijing MunicipalityAges 18–65 - NCT07540286RecruitingPhase 2
Study of XH-02 for Treating Low Parathyroid Hormone Levels
This study tests a new drug called XH-02 for hypoparathyroidism—a condition where your body doesn't make enough parathyroid hormone, causing low calcium levels. If you haven't improved with standard calcium and vitamin D treatments, this trial may help.
BeijingAges 18–90 - NCT07582562Recruiting
Thyroid Surgery and Low Calcium Risk Factors
This study examines why some patients develop low calcium levels (hypoparathyroidism) after surgery to remove both sides of the thyroid gland. By understanding these risk factors, doctors hope to better predict and prevent this complication.
TallinnAges 18 years+ - NCT07264634Recruiting
YORVIPATH in breast milk study
This study measures how much of the medicine YORVIPATH (palopegteriparatide) gets into breast milk. It helps mothers who need this medicine and want to breastfeed understand if it is safe for their baby.
Morgantown, West VirginiaAges 18–50 - NCT07381998Enrolling by invitation
Effects of total thyroid removal on parathyroid function and quality of life
This study looks at how completely removing the thyroid gland affects the nearby parathyroid glands (which control calcium) and your overall quality of life. If you're having a total thyroid removal and meet a few health conditions, you may be able to join.
Aarhus, Central JutlandAges 18 years+ - NCT04785443RecruitingPhase 3
Check whether dye-guided imaging helps find parathyroid glands
This study tests whether using a special camera with a fluorescent dye (called ICG angiography) during total thyroid surgery can help doctors find the parathyroid glands more reliably. It aims to lower the risk of “low parathyroid hormone,” which can lead to low calcium after surgery.
BrestAges 18 years+ - NCT05585593Recruiting
Registry for long-term low parathyroid hormone conditions
This study keeps an ongoing registry (a secured collection of patient information) for people with long-term low parathyroid hormone problems or similar conditions. It may help researchers better understand these conditions and improve future care.
Würzburg, BavariaAges 18 years+ - NCT06222606Recruiting
Surgery for Thyroid Cancer With or Without Special Light to Protect Calcium Glands
This study tests whether using a special light (called autofluorescence) during thyroid cancer surgery helps lower the risk of a common side effect—hypoparathyroidism, which can cause low calcium levels. You may be able to join if you are scheduled for a complete thyroid removal and have normal calcium before surgery.
Aarhus, DenmarkAges 18 years+ - NCT06765941Recruiting
PTeye vs surgeon's eyes for parathyroid protection in thyroid surgery
This trial tests whether a device called PTeye helps surgeons better identify and protect the parathyroid glands during first-time total thyroid removal surgery, compared to relying on the surgeon's eyes alone.
Krakow, MałopolskaAges 18 years+ - NCT06797934Recruiting
Registry for people with parathyroid disease
This trial is creating a registry (a database) for people with parathyroid disease. It will collect information to help doctors better understand and treat these conditions.
Bologna, BolognaAges 18 years+
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Common questions
- Are there clinical trials for hypoparathyroidism?
- Yes. Clin2 currently lists 27 recruiting hypoparathyroidism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hypoparathyroidism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hypoparathyroidism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.