Seltoplasmid plus leg artery opening for diabetic foot ulcers
Part of Heart & circulation, Hormones & metabolism, Skin clinical trials.
This trial tests whether an experimental injection called seltoplasmid, given along with a procedure to restore blood flow in the leg (revascularization), can help heal diabetic foot ulcers that have not responded to standard care. It is designed for people with severe leg artery blockages that threaten the limb.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 18 years old.
- You must have type 2 diabetes with a foot ulcer that has not shown signs of healing after at least two weeks of standard wound care.
- You must have a severe narrowing or blockage (at least 70%) in one or more arteries below the knee in your leg.
- You must have evidence of severely reduced blood flow to your foot, such as low ankle pressure or skin oxygen levels.
- You must not have gangrene or be in need of a major amputation above the ankle.
- You must be in generally stable health, with no recent heart attack or stroke, and no severe liver, kidney, or bleeding problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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