Clin2
NCT07868328Possibly a fitNot yet recruiting

Study of an investigational drug for primary tauopathies

Progressive Supranuclear PalsyCorticobasal DegenerationFrontotemporal Lobar DegenerationTauopathies

Part of Brain & nervous system, Eyes & vision, Hormones & metabolism, Mental health clinical trials.

This trial tests an experimental drug called NIO752 in people with certain brain conditions known as primary tauopathies, which include progressive supranuclear palsy (PSP), corticobasal syndrome (CBS), and frontotemporal dementia caused by MAPT gene changes. The goal is to see if the drug is safe and how it affects the body.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
48 people
Ages
41 years to 81 years
Study type
Interventional

Who can take part

  • You are between 41 and 81 years old.
  • You can walk at least 10 steps with minimal help (like using a cane or holding someone's arm).
  • Your symptoms started within the last 5 years.
  • You have a caregiver or family member who can come to study visits and provide information about you.
  • If you take medications for your symptoms, the dose must be stable for at least 8 weeks before the study starts.
  • You must have a diagnosis of PSP, CBS, or a MAPT gene mutation.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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