Clinical trials
Progressive Supranuclear Palsy clinical trials
Below are recruiting progressive supranuclear palsy clinical trials, each written for real people, not researchers. We’re tracking 32 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07173803RecruitingPhase 2
PSP clinical trial testing new treatments
This trial tests potential new treatments for progressive supranuclear palsy (PSP), a brain disorder affecting movement, balance, and thinking. It aims to see if these treatments are safe and slow the disease. You may be able to join if you have a specific type of PSP and are in fairly good health.
Palo Alto, CaliforniaAges 41–86 - NCT07264283Enrolling by invitationPhase 2
Testing LM11A-31 for progressive supranuclear palsy
This trial tests a drug called LM11A-31 to see if it can help people with progressive supranuclear palsy (PSP), a rare brain condition. You may join if you have had symptoms for 5 years or less, can walk with minimal help, and have good thinking abilities.
San Francisco, CaliforniaAges 41–86 - NCT07217665Enrolling by invitationPhase 2
AADvac1 vaccine for progressive supranuclear palsy
This trial tests a vaccine called AADvac1 for people with progressive supranuclear palsy (PSP), a brain condition that affects movement and thinking. The study wants to see if the vaccine can slow the disease down.
San Francisco, CaliforniaAges 41–86 - NCT04363684Recruiting
Study of frontotemporal dementia and related syndromes over time
This study follows people with frontotemporal dementia (FTLD) and related conditions, and collects health and (for some people) body fluid information, to understand how these illnesses change over time. It may help researchers track disease signs and find better ways to measure progression.
Birmingham, AlabamaAges 18 years+ - NCT07498426RecruitingPhase 3
Study of NIO752 for progressive supranuclear palsy
This trial tests a new medicine called NIO752 for people with progressive supranuclear palsy (PSP), a condition that affects movement, balance, and thinking. The goal is to see if it can help slow the disease's progression.
Scottsdale, ArizonaAges 41–81 - NCT03174938Recruiting
BioFINDER 2 study for healthy aging and memory problems
This study uses brain scans and a spinal fluid test to better understand memory and thinking changes in different groups, from people with healthy thinking to early or established dementia. If you qualify, it may help researchers learn what’s driving these conditions and how they progress.
ÄngelholmAges 20–100 - NCT03638505Recruiting
Quality of life study for people with PSP and their caregivers
This study looks at quality of life for people with progressive supranuclear palsy (PSP) and the day-to-day burden on the caregiver. It may help researchers understand what support needs are most important and how caregiving affects wellbeing.
Marseille, PACAAges 18 years+ - NCT04468932Recruiting
TMS brain stimulation for progressive supranuclear palsy
This trial tests whether repeated non-invasive magnetic brain stimulation (TMS) can improve symptoms in people with progressive supranuclear palsy (PSP). It may help by targeting brain circuits involved in movement and balance.
Portland, OregonAges 40–85 - NCT06529744Recruiting
Using blood tests to better diagnose early dementia
This study is testing whether simple blood tests can help doctors better understand the type and progression of memory or thinking problems in people with early dementia. It aims to improve confidence in the diagnosis and future outlook.
North York, OntarioAges 30–95 - NCT06647641Recruiting
Genetics study for PSP, CBS, MSA, and related conditions
This study looks at genetic factors in people with PSP, CBS, MSA, or similar brain conditions, and also in their family members. It involves genetic testing to learn more about these diseases and may help find new treatments.
Boston, MassachusettsAges 35 years+ - NCT07136844Recruiting
Walking and arm movement study for nerve and muscle conditions
This study uses motion analysis to understand walking and arm function in adults with certain neurological or metabolic diseases. The goal is to find patterns that help doctors better manage these conditions.
LiègeAges 18 years+ - NCT02605785Recruiting
Imaging study to track tau protein in PSP
This study uses brain imaging to look at a protein called tau in people with progressive supranuclear palsy (PSP). It aims to better understand the disease and how tau changes over time, which may help future treatments.
Rochester, MinnesotaAges 35 years+ - NCT07567664Enrolling by invitation
Brain Changes in Neurodegenerative Diseases: A Tracking Study
This research study tracks how brain damage progresses in rare neurodegenerative diseases like frontotemporal dementia, primary progressive aphasia, PSP, CBS, and ALS. Researchers use brain imaging and tests to understand how these diseases spread in the brain, which could help develop better treatments.
Milan, LombardyAges 20–85 - NCT02964637Recruiting
Tests to help diagnose frontotemporal dementia
This study looks at testing (including brain scans) to figure out what type of frontotemporal dementia or related language/speech condition a person has. It may help by making diagnoses more accurate, which can guide better care.
Toronto, OntarioAges 18–90 - NCT04715399Recruiting
Research study collecting data for neurodegenerative diseases
This study collects health information from people with neurodegenerative diseases, some family members, and healthy controls to help researchers better understand these conditions. It may help future diagnosis and research, and participation may include noninvasive checks and other procedures depending on your situation.
Philadelphia, PennsylvaniaAges 18 years+ - NCT03225144Recruiting
Study of gene and disease changes in ALS and frontotemporal dementia
This study looks at complex brain and body changes in people with ALS and frontotemporal dementia (FTD), or related disorders. If you have one of these diagnoses—or a known gene mutation that can cause ALS/FTD—you may be able to help researchers learn how the conditions progress.
Bethesda, MarylandAges 18–110 - NCT03872102Recruiting
Brain imaging study to track Parkinson-related disease changes
This study uses brain scans and clinical check-ins to better diagnose and predict how Parkinson-related conditions may progress over time. It may help researchers find markers that explain why symptoms change, and could improve future care.
Dallas, TexasAges Any age - NCT04706234Recruiting
Check swallowing and voice function in neurodegenerative diseases
This study looks at how well the throat and voice-related functions work in people with certain long-term brain or nerve conditions. It uses a specific throat exam during FEES to better understand swallowing and laryngopharyngeal (throat-area) function.
Innsbruck, TyrolAges 18 years+ - NCT05121012Recruiting
PET brain scan study for synaptic loss in MSA or PSP
This study uses brain scans (PET, and possibly spinal fluid) to measure changes linked to “synaptic loss” in people with multiple system atrophy (MSA) or progressive supranuclear palsy (PSP). It may help researchers understand disease changes and how they relate to symptoms, which could guide future treatments.
ExeterAges 45–80 - NCT06162013RecruitingPhase 2
NAD supplement trial for atypical parkinsonism
This trial tests whether a supplement called nicotinamide riboside (NR) can help people with rare forms of parkinsonism (PSP, MSA, or CBS). It is a double-blind study, meaning neither you nor the doctors will know if you are getting the real supplement or a placebo.
Oslo, OsloAges 30–85 - NCT06174948Recruiting
CUE1 device for Parkinson's and related movement disorders
This trial tests a small device called CUE1 that gives gentle vibrations on the chest to help improve movement and balance in people with Parkinson's disease and similar conditions. It may help if you have trouble with walking or stability.
LondonAges 18 years+ - NCT06203106Recruiting
NYSCF Scientific Discovery Biobank
This study collects blood, saliva, or skin samples from people with certain neurological conditions and from healthy volunteers to help researchers better understand and find treatments for these diseases.
New York, New YorkAges 4 weeks+ - NCT06596746Recruiting
Tracking markers for neurodegenerative diseases
This study tracks changes in people with Parkinson's disease, other movement disorders, or cognitive decline to find better ways to measure disease progression.
Cassino, FrosinoneAges 10 years+ - NCT06645626Recruiting
Health service use and quality of life in atypical Parkinson's
This study looks at how people with certain rare brain conditions (like progressive supranuclear palsy, corticobasal syndrome, or multiple system atrophy) use healthcare services and how their quality of life is affected. It may help doctors better support patients and their carers.
Southampton, HampshireAges 18 years+
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Progressive Supranuclear Palsy trials by city
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Progressive Supranuclear Palsy trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for progressive supranuclear palsy?
- Yes. Clin2 currently lists 32 recruiting progressive supranuclear palsy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a progressive supranuclear palsy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a progressive supranuclear palsy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.