Clinical trials
ACL Injury clinical trials
Below are recruiting acl injury clinical trials, each written for real people, not researchers. We’re tracking 56 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04875052Recruiting
Study vibration after ACL injury and future arthritis risk
This study looks at whether using vibration after an ACL injury helps predict or reduce the risk of developing post-traumatic osteoarthritis (wear-and-tear arthritis) later. It may help researchers learn which patients are more likely to develop arthritis after ACL reconstruction.
Chapel Hill, North CarolinaAges 16–35 - NCT07115316Recruiting
Hamstring exercises with physiotherapy for football players with mild ACL injury
This study tests if adding special hamstring exercises to standard physiotherapy can help young football players recover better after a mild ACL tear. It focuses on improving sports performance and quality of life with no surgery needed.
Ras al-Khaimah, Emirate of Ras Al KhaimahAges 19–25 - NCT05701579Recruiting
Testing treatment choices for early ACL cartilage changes before surgery
This trial looks at a treatment strategy for people with specific early changes in the ACL seen on MRI who are planning knee surgery. It may help by testing the best way to address those ACL-related cartilage/mucosa-like changes before or during surgical care.
Bełchatów, Łódź VoivodeshipAges Any age - NCT04770233Recruiting
Comparing early surgery options for torn ACL
This study looks at the best way to treat a fresh ACL (an important knee ligament) tear by comparing an “early surgery” plan that starts within 12 weeks. It may help guide care and recovery for people who are able to do both the surgery and the follow-up rehabilitation.
Lørenskog, AkershusAges 16–50 - NCT06147427Recruiting
ACL reconstruction with or without Lemaire procedure
This study compares two surgical techniques for repairing a torn ACL: standard ACL reconstruction alone versus ACL reconstruction plus a Lemaire procedure (an extra side-stabilizing repair). It aims to see which approach provides better knee stability for active patients over at least 2 years.
LyonAges 18–50 - NCT06206200Recruiting
Thinking and moving after ACL surgery
This study looks at how doing a thinking task at the same time as a walking or balance task affects recovery in people who have had ACL reconstruction surgery. It may help you understand what to expect during later stages of rehab.
Roeselare, West-VlaanderenAges 18–40 - NCT07097077Recruiting
Brain changes after ACL surgery with special training
This study uses brain scans (fMRI) to see how a special type of movement training affects the brain after ACL surgery. If you've had an ACL repair and are active in sports, you may be eligible.
Bologna, BolognaAges 18–30 - NCT07019727Recruiting
ACL injury prevention program for Czech athletes
This study tests a special training program designed to prevent ACL injuries in young athletes (ages 17-20) who play high-risk sports like soccer, basketball, or skiing. It aims to see if the program can reduce the chances of getting an ACL injury.
BrnoAges 17–20 - NCT07671235Recruiting
Comparing graft options for repeat ACL surgery
This study compares two types of tissue grafts (your own or a donor's) used in a second ACL knee surgery to see which leads to better outcomes and fewer failures over at least two years.
Bologna, BolognaAges 18–50 - NCT04408885Recruiting
Rehab program for a torn ACL ligament
This study looks at a rehabilitation-focused treatment plan after an ACL (an important knee ligament) tear. It may help you by testing the best rehab approach for improving knee function and stability.
Aarhus NAges 18–50 - NCT04572256RecruitingEarly Phase 1
Montelukast after ACL surgery to protect knee cartilage
This early trial tests whether montelukast, a tablet used for allergies, can help protect knee cartilage after ACL surgery. It is specifically for people who have a meniscus injury along with their ACL tear.
Lexington, KentuckyAges 25–50 - NCT04607538Recruiting
Study of knee joint shape and patella dislocations in Faroese teens
This study looks at how knee joint shape differences may relate to repeated kneecap (patella) instability or near-dislocation, and what that means long-term. It specifically includes teens from the Faroe Islands and asks about symptoms and knee function over time.
HvidovreAges 15–20 - NCT06686680Recruiting
Shockwave therapy for knee arthritis after ACL repair
This study tests whether shockwave therapy can help knee pain and function in people who developed knee osteoarthritis after an ACL reconstruction. If you had ACL surgery at least a year ago and still have knee pain, this treatment might offer a new option without surgery.
Cambridge, MassachusettsAges 18–55 - NCT06983184Enrolling by invitation
Period-synced training for teenage athletes
This trial tests a training program that adjusts to your menstrual cycle to help teenage athletes prevent injuries and improve strength. It uses a smart ring to track sleep, activity, and body signals.
Frisco, TexasAges 13–19 - NCT05218993Enrolling by invitation
Testing a new balance and reaction method for football players
This trial tests a new “dual task” training or testing method for professional football players. It may help coaches and players measure balance and reaction under real game-like conditions.
AnkaraAges 14 years+ - NCT06195423Recruiting
Stopping knee arthritis after an ACL tear
This study tests a home exercise program to prevent knee arthritis after an ACL tear. If you had ACL surgery 9 to 36 months ago and still have some knee symptoms, this program may help protect your knee in the long run.
Vancouver, British ColumbiaAges 16–35 - NCT07475351Recruiting
Comparing two grafts for ACL reconstruction
This trial compares two types of grafts to rebuild the ACL in the knee, to see if one leads to better results. It is for active athletes with a recent ACL tear and healthy knees.
Granada, GranadaAges 12–40 - NCT03441165Recruiting
Measure knee looseness during ACL and meniscus surgery
This trial checks how loose the knee feels during surgery for ACL reconstruction, ACL revision, or meniscus transplantation. The goal is to better assess knee stability during the operation, which may help surgeons choose the best repair.
Bologna, ItaliaAges 14–65 - NCT04183803Recruiting
Robot help to set the right position for ACL surgery
This study tests whether using a robot to help place the tunnel during ACL (knee ligament) reconstruction is better or more accurate than the usual approach. You may benefit if you need ACL surgery and your care team has robot experience.
AmiensAges 10 years+ - NCT05527171Recruiting
Virtual reality mindfulness after ACL knee surgery
This study uses a virtual-reality mindfulness meditation program to help improve fear and movement quality after ACL reconstruction. It may help you feel less afraid of movement and land more safely when you return to sports.
Chapel Hill, North CarolinaAges 14–25 - NCT05949177Recruiting
Mindfulness and graded exercise for fear after ACL surgery
This trial studies whether a combination of mindfulness practice and a step-by-step return-to-activity plan can reduce fear and improve recovery after ACL reconstruction. It may help people who feel worried about re-injury and want a structured way to get back to sports.
Chapel Hill, North CarolinaAges 14–35 - NCT06936995Recruiting
Comparing pain relief methods for ACL surgery recovery
This trial tests two ways to manage pain after ACL reconstruction: a combination of medications (multimodal analgesia) versus a nerve block in the thigh (femoral block). The goal is to see which approach provides better pain control and recovery.
AnkaraAges 18–65 - NCT07306221Recruiting
Balance training after ACL surgery using visual guides
This study tests if a special video-based balance training program helps people recover knee function better after ACL reconstruction surgery. It is designed for patients who had surgery within the past year using their own hamstring tendon.
BeijingAges 18–45 - NCT07366619Recruiting
MADI ACL study: a new MRI method for ligament repair
This trial tests a new MRI technique called Magic Angle Direction Imaging (MADI) to see if it can give better images of the knee before ligament repair surgery. It may help doctors plan your surgery more accurately.
LondonAges 18–65
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Common questions
- Are there clinical trials for acl injury?
- Yes. Clin2 currently lists 56 recruiting acl injury studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acl injury trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acl injury trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.