Clinical trials
Acute Disease clinical trials
Below are recruiting acute disease clinical trials, each written for real people, not researchers. We’re tracking 398 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05125302RecruitingPhase 3
Ubrogepant for acute migraine relief in kids and teens
This study tests how safe ubrogepant is and whether it helps treat an individual migraine attack in children and teens. It focuses on measuring side effects and whether headaches improve 2 hours after taking the study medicine.
Huntsville, AlabamaAges 6–17 - NCT01218776Recruiting
Survey study for people with acute heart symptoms
This study is an international survey about acute coronary syndromes, which are sudden signs of heart-related problems. Your answers can help researchers better understand symptoms and care needs after these events.
Bologna, Emilia-RomagnaAges 18 years+ - NCT07106749RecruitingPhase 1
CD180 car T cells for blood cancers that came back
This trial tests a new CAR T cell therapy that targets a protein called CD180 on cancer cells. It is for people with certain types of relapsed or refractory leukemia or lymphoma that has not responded to standard treatments.
Tianjin, Tianjin MunicipalityAges 18–70 - NCT04008173Enrolling by invitation
Survey study of acute heart attack symptoms
This study collects information about symptoms and experiences during acute coronary syndromes, which are sudden, serious heart events like heart attacks or unstable angina. It may help researchers understand patterns of care and symptoms to improve future treatment and support.
Bologna, BolognaAges 18 years+ - NCT06608732RecruitingPhase 2
CAR-T therapy plus stem cell transplant for B-cell ALL with MRD
This trial tests a combination of a CAR-T cell therapy (Inaticabtagene Autoleucel) followed by your own stem cells being transplanted back into you. It is for teenagers and adults who have B-cell acute lymphoblastic leukemia (ALL) that is in first complete remission but still has tiny amounts of cancer cells (called MRD) that can be detected by sensitive tests.
Tianjin, Tianjin MunicipalityAges 16–70 - NCT05545384RecruitingPhase 3
Immediate vs delayed azathioprine or rituximab for children with anti-MOG attacks
This Phase 3 trial tests whether starting anti-inflammatory treatment right away is better than waiting, using either azathioprine or rituximab, for children with anti-MOG antibody–related acute demyelinating episodes. It may help reduce future attacks and disability.
BesançonAges 6–17 - NCT07604103RecruitingPhase 3
Heart Attack and Pneumonia Recovery Study With Vaccination
This study looks at blood markers (special proteins) in patients who have had both a heart attack and pneumonia, to see how vaccination affects recovery. The goal is to understand whether flu and pneumonia vaccines are safe and helpful for people recovering from these two serious conditions together.
Malang, East JavaAges 18–65 - NCT06855537RecruitingPhase 4
Treating unstable plaques that are not fully blocked
This trial compares treatments for heart patients who have a dangerous, but not fully blocking, fatty plaque in their arteries. It aims to see if treating these plaques with a stent or balloon can prevent future heart problems.
Beijing, Beijing MunicipalityAges 18–80 - NCT02714387Recruiting
Study of serious complications from non-traumatic blood vessel brain problems
This study follows people who have non-injury (non-traumatic) blood-vessel-related problems in the brain to understand serious complications. It may help researchers identify risks and improve care over time.
AngersAges 15 years+ - NCT06083363Recruiting
Recovery after severe lung infection
This study follows patients who had severe pneumonia or acute respiratory distress syndrome (ARDS) in the intensive care unit (ICU) to understand how they recover over time. It aims to identify factors that affect recovery trajectories.
Tortosa, TarragonaAges 18 years+ - NCT06191302Recruiting
Long COVID study in Denmark
This study follows people who were hospitalized for COVID-19 to learn more about long-term health effects (post-COVID conditions). It uses blood samples already collected during their hospital stay.
HvidovreAges 18 years+ - NCT06377345Recruiting
Remote monitoring for asthma flare-ups
This trial tests a remote monitoring device that tracks your breathing while you're at home. If you have asthma and are having a flare-up today, you may be able to use a small wearable sensor and a smartphone app to help your doctor keep an eye on your condition.
SingaporeAges 7–90 - NCT04220463Recruiting
Hypnosis during noninvasive breathing support for ICU lung illness
This trial tests whether hypnosis can help people in the ICU who need noninvasive breathing support (breathing help without a tube) for breathing flare-ups related to COPD and/or obesity. It aims to make this treatment easier and safer while you are awake.
Rennes, Brittany RegionAges 18 years+ - NCT06893965Recruiting
Eye pressure check after Eylea 8mg injection
This trial measures eye pressure right after an injection of a higher-dose Eylea (aflibercept 8mg) to see how it affects the eye. It may help people who need frequent anti-VEGF shots for conditions like wet AMD or diabetic eye disease.
Toulon, VarAges 18 years+ - NCT04861506Recruiting
Clot-removal treatment for blocked blood flow in the leg
This trial tests how safe and effective a clot-removal procedure done through the blood vessels is for people with acute or subacute blocked blood flow in the lower leg. It may help by improving circulation while carefully tracking risks and results.
Hangzhou, ZhejiangAges 18 years+ - NCT06419036Enrolling by invitation
Using medical devices to monitor COPD at home
This study tests whether wearable medical devices can help monitor your COPD symptoms at home. You will use a smartphone app and a small chest patch to track your breathing, which may help you and your doctor better manage your condition.
GlasgowAges 18 years+ - NCT06419062Enrolling by invitation
Using wearables to monitor COPD at home
This study tests if a wearable device can help track your COPD symptoms between doctor visits. You'll use a smartphone or computer to share data, which may help your care team stay on top of your health.
GlasgowAges 18 years+ - NCT06016257Recruiting
Virtual home exercise program for shoulder rehab
This study tests a virtual home exercise program (VirtuaCare) for people with shoulder problems who need physical therapy. It aims to see if doing exercises at home with virtual guidance works as well as standard care.
Los Angeles, CaliforniaAges 18 years+ - NCT05732480Recruiting
Studying how gut bacteria affect gallstone disease
This study looks at gut bacteria (your microbiome) in people with gallstones to better understand what’s going on in the body. It includes adults having gallbladder removal surgery, and it may help researchers find better ways to predict or treat gallstone disease.
Ashford, KentAges 18 years+ - NCT05353569Recruiting
Testing a new way to detect middle ear fluid or infection
This study looks at whether a new light-based check can help detect middle ear problems such as ear infections or fluid behind the eardrum. If it works well, it could help clinicians identify the problem faster and more accurately for children.
Wauwatosa, WisconsinAges 1–6 - NCT03676504RecruitingPhase 1/Phase 2
CAR T cell therapy for relapsed CD19 blood cancers
This trial tests a type of personalized immune treatment (CD19 CAR T cells made from your T cells) for adults (and children with ALL) whose CD19-positive blood cancer has come back or didn’t respond. It may help your immune system recognize and attack cancer cells that still have CD19.
HeidelbergAges 3 years+ - NCT06386302Recruiting
Chidamide, venetoclax, and azacitidine for new AML
This trial tests a combination of three oral medications (chidamide, venetoclax, and azacitidine) for people newly diagnosed with acute myeloid leukemia (AML) who cannot receive strong chemotherapy. The goal is to see if this gentler treatment can work well with fewer side effects.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT01351545Recruiting
Cryopreserved cord blood access program for transplant patients
This trial studies an organized way to obtain and distribute unlicensed (not FDA-approved for general use) stored cord blood units that have been frozen and kept. It may help people who need a cord blood transplant but don’t fit the “licensed cord blood only” options.
Birmingham, AlabamaAges Any age - NCT07661940RecruitingPhase 2
SP16 for kidney protection during heart surgery
This trial tests a drug called SP16 to see if it can prevent acute kidney injury in people with chronic kidney disease who are having elective heart surgery with a heart-lung machine. It aims to help preserve kidney function after surgery.
Erlangen, BavariaAges 18 years+
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Common questions
- Are there clinical trials for acute disease?
- Yes. Clin2 currently lists 398 recruiting acute disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.