Clinical trials
Acute Disease clinical trials
Below are recruiting acute disease clinical trials, each written for real people, not researchers. We’re tracking 400 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06386302Recruiting
Chidamide, venetoclax, and azacitidine for new AML
This trial tests a combination of three oral medications (chidamide, venetoclax, and azacitidine) for people newly diagnosed with acute myeloid leukemia (AML) who cannot receive strong chemotherapy. The goal is to see if this gentler treatment can work well with fewer side effects.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT01351545Recruiting
Cryopreserved cord blood access program for transplant patients
This trial studies an organized way to obtain and distribute unlicensed (not FDA-approved for general use) stored cord blood units that have been frozen and kept. It may help people who need a cord blood transplant but don’t fit the “licensed cord blood only” options.
Birmingham, AlabamaAges Any age - NCT07550673RecruitingPhase 4
Upadacitinib vs. Infliximab for Severe Ulcerative Colitis
This study compares two medications—upadacitinib and infliximab—as second-line treatments for acute severe ulcerative colitis (a serious flare of inflammatory bowel disease). The trial will help doctors understand which treatment works better when standard first-line therapy hasn't controlled the inflammation.
Ankang, ShaanxiAges 18–85 - NCT07185022Recruiting
Clot-busting drug through artery for medium-vessel stroke
This trial tests a clot-busting drug given directly into the arteries of the brain for people who have had a stroke due to a blockage in a medium-sized artery. It aims to see if this treatment can help improve recovery when started up to 72 hours after symptoms begin.
Fuyang, AnhuiAges 18 years+ - NCT06282718Recruiting
Observational study of respiratory infections in primary care
This study tracks how patients with respiratory infections (like bronchitis, sore throats, or COVID-19) are treated in family doctor offices across Europe. The goal is to learn more about these infections and improve care. You may be able to join if you have a cough, sore throat, or other symptoms that suggest a respiratory infection, and you go to a participating clinic.
AntwerpAges Any age - NCT04099966RecruitingPhase 2
Stem cell transplant to treat high-risk blood cancers
This trial tests a specialized donor stem cell transplant to treat high-risk problems in the blood and bone marrow, including some cancers and non-cancers. It may help by using donor immune cells designed to better control the disease after transplant.
Valhalla, New YorkAges 1 day–30 years - NCT07022496RecruitingPhase 4
Can oral caffeine help with acute migraine attacks?
This trial tests whether taking caffeine by mouth can reduce the severity of a migraine attack when it happens. It may offer a simple, at-home option for people with different types of migraine.
CairoAges 18–60 - NCT06728592Recruiting
Emergency stroke unit for ischemic stroke within 6 hours
This trial tests a dedicated emergency stroke unit for people with ischemic stroke who can get treatment within 6 hours of symptoms starting. It aims to see if this special care area improves outcomes.
Hong KongAges 18–100 - NCT07188740RecruitingPhase 1
Metformin to target leukemia-related mutation during remission
This trial tests if metformin can reduce a specific mutation (DNMT3A R882) in people with acute leukemia who are in remission. The goal is to see if it helps prevent relapse.
Tianjin, Tianjin MunicipalityAges 14 years+ - NCT06447090RecruitingPhase 2
VMAC plus donor cells for AML relapse after transplant
This study tests a combination treatment called VMAC (a chemotherapy) plus DLI (donor immune cells) for people whose AML has returned after a stem cell transplant. The goal is to see if this approach can help control the leukemia again.
Tianjin, Tianjin MunicipalityAges 18–65 - NCT07374874Recruiting
Heart and nervous system health after stem cell transplant
This study looks at how your autonomic nervous system (the part that controls heartbeat and digestion) affects the risk of graft-versus-host disease (a condition where donor cells attack your body) after a half-matched stem cell transplant. You may be able to join if you are older than 16 and receiving a half-matched transplant from a family donor.
Tianjin, Tianjin MunicipalityAges 16 years+ - NCT05017142Recruiting
Pediatric brain inflammation registry for Swiss patients
This study is a registry that collects health information from children and teens in Switzerland diagnosed with certain inflammatory brain and spinal cord conditions. It helps researchers understand these illnesses better over time and may guide future treatments.
Aarau, Canton of AargauAges Up to 36 years - NCT05681962Recruiting
Improving breathing support during flexible bronchoscopy
This trial studies how to give oxygen and breathing support during a flexible bronchoscopy (a camera test through the airways). It may help make the procedure safer and more comfortable by refining the way oxygen is managed during the test.
CatanzaroAges 18 years+ - NCT06158620RecruitingPhase 1/Phase 2
Nasal spray for pain after ureter stent placement
This trial tests whether a nasal spray form of the painkiller ketorolac can safely reduce pain from a ureteral stent after stone surgery. If you are having a ureteroscopy with stent placement, this might help you manage discomfort without stronger medications.
Dallas, TexasAges 18 years+ - NCT06211166Recruiting
Tracking cancer genes after stem cell transplant with digital PCR
This trial uses a precise blood test called digital PCR to measure tiny amounts of leftover cancer cells in patients who have had a stem cell transplant. It helps doctors see how well the transplant is working and if more treatment is needed.
Beijing, Beijing MunicipalityAges Any age - NCT06443268Recruiting
Stroke and quality of life study with caregivers
This study looks at quality of life for people who have had a recent stroke or mini-stroke, and their caregivers. You and a close relative or friend both take part in interviews and surveys over time.
Zurich, Canton of ZurichAges 18 years+ - NCT06783790RecruitingPhase 2
Avapritinib combo for relapsed AML after transplant
This trial tests a combination of three drugs (avapritinib, azacitidine, and venetoclax) for people whose acute myeloid leukemia (AML) has returned after a stem cell transplant. It targets a specific genetic change (C-KIT mutation) to try to stop the cancer from growing.
TianjinAges 18 years+ - NCT07059975RecruitingEarly Phase 1
Better monitoring and treatment for pediatric AML
This trial tests a new way to monitor and treat children and young adults with acute myeloid leukemia (AML) or myeloid sarcoma. It aims to improve outcomes by using personalized treatment adjustments based on how well the disease responds to initial therapy.
Houston, TexasAges 1 month–30 years - NCT07246265Recruiting
Morphine clearance study for sickle cell crisis in ICU
This study looks at how the body clears morphine in adults with sickle cell disease who are in the intensive care unit (ICU) for a pain crisis or acute chest syndrome and are receiving morphine through a patient-controlled analgesia (PCA) pump. The goal is to understand how kidney function affects morphine breakdown.
Tours, FranceAges 18 years+ - NCT07432191Recruiting
Testing a new ventilator for safe breathing support
This study tests a new breathing machine (INBENTUS VERSATILE ventilator) for people who need help breathing. It checks if the machine is safe and works well for patients who need a ventilator and then slowly come off it.
MurciaAges 18 years+ - NCT06954792Enrolling by invitation
Studying heart changes after tricuspid valve replacement
This study looks at how the heart adjusts after a procedure to replace the tricuspid valve (the valve between the right upper and lower heart chambers). It focuses on patients who need medication to support their blood pressure within 24 hours after the procedure, to better understand and manage this unstable period.
New York, New YorkAges 18 years+ - NCT06855810RecruitingPhase 2/Phase 3
New treatment study for children with T-cell ALL
This study tests a new treatment plan for children and teens newly diagnosed with T-cell acute lymphoblastic leukemia (T-ALL). It aims to see if the approach is safe and works well, and might offer a more tailored therapy for this specific type of leukemia.
Hefei, AnhuiAges 1 month–18 years - NCT06674460RecruitingPhase 3
Edaravone Dexborneol tablet for stroke recovery
This trial tests a new sublingual tablet (Edaravone Dexborneol) to help people recover after a small stroke caused by disease of the small blood vessels in the brain. It aims to see if the drug can improve thinking and daily function.
BeijingAges 30–80 - NCT07439757Recruiting
Using AI to Guide Care for Pancreatic Conditions
This study uses artificial intelligence (AI) to help doctors make better decisions for people with suspected pancreatic conditions. If you are already getting a special CT scan, the AI will analyze the images to see if it can improve diagnosis and treatment planning.
ShanghaiAges 18–80
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Common questions
- Are there clinical trials for acute disease?
- Yes. Clin2 currently lists 400 recruiting acute disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.