Clinical trials · California
Acute Ischemic Stroke clinical trials in California
We’re tracking 23 recruiting acute ischemic stroke studies with a site in California — including Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07430917RecruitingPhase 2
Testing J147 for recent stroke from blocked artery
This trial tests a new drug, J147, for people who recently had a stroke caused by a blocked artery and have already had a procedure to reopen that artery. It aims to see if the drug can improve recovery.
Long Beach, CaliforniaAges 18–90 - NCT05065216RecruitingPhase 2/Phase 3
Study drug for acute ischemic stroke started within 24 hours
This trial tests whether an investigational study drug can improve outcomes after an acute ischemic stroke (a stroke caused by blocked blood flow). You may be eligible if you are able to start treatment quickly after symptom onset and have a moderate stroke severity on a standard stroke exam.
Arcadia, CaliforniaAges 18–90 - NCT05338697Recruiting
Early testing after stroke to predict recovery outcomes
This study checks early brain and arm/hand signals soon after a stroke to better predict how well people recover by about 90 days. It may help future, better-targeted stroke recovery studies by improving how recovery chances are measured early.
Los Angeles, CaliforniaAges 18 years+ - NCT07392450RecruitingPhase 2
Study of TAK-755 for adults with acute ischemic stroke
This trial tests if TAK-755 can help people who have had a moderate to severe stroke within the last 24 hours. It aims to see if the drug can improve recovery by protecting brain tissue that is still salvageable.
San Francisco, CaliforniaAges 18 years+ - NCT07491952Recruiting
Continuous Dual Aspiration for Stroke With Zoom System
This trial tests a new way to remove blood clots from the brain using the Zoom System with a continuous double-suction technique (CDAT). It aims to see how well this approach works for people having a stroke caused by a large vessel blockage.
Walnut Creek, CaliforniaAges 18 years+ - NCT03318432Recruiting
Stroke recovery research registry for people with ongoing symptoms
This study is a registry that enrolls adults who have had a stroke and still have symptoms. It helps researchers learn about stroke recovery over time and may connect you to future stroke research studies.
San Francisco, CaliforniaAges 18 years+ - NCT03737786Recruiting
Sedation with collateral support for stroke clot removal
This trial tests a specific sedation approach, along with support during the procedure, for people having emergency clot removal (mechanical thrombectomy) for a certain type of acute ischemic stroke. It may help make the procedure safer and more effective by improving how patients are managed during endovascular treatment.
Los Angeles, CaliforniaAges 18–110 - NCT05518305Recruiting
Predicting recurrent stroke risk in people with artery narrowing
This study looks at blood markers and brain/artery scan results to predict who with intracranial artery narrowing is more likely to have another stroke. It may help doctors spot higher-risk people earlier and better target prevention.
Los Angeles, CaliforniaAges 30 years+ - NCT05611242RecruitingPhase 3
Thrombectomy for acute stroke caused by blocked neck and brain arteries
This Phase 3 trial studies whether removing a clot using a catheter (endovascular thrombectomy) works better for certain types of acute ischemic stroke. It focuses on people with a blocked neck artery plus a blockage in the brain, and who can’t get or didn’t respond to IV clot-busting medicine.
Pomona, CaliforniaAges 18–79 - NCT05691244RecruitingPhase 3
Tested drug for acute ischemic stroke within 24 hours
This Phase 3 trial studies sovateltide (and a placebo) in adults with an ischemic stroke, aiming to improve safety and outcomes. It focuses on people who can start treatment quickly after stroke symptoms begin and who do not have bleeding in the brain on imaging.
Oxnard, CaliforniaAges 18–80 - NCT05911568Recruiting
Clot-removal treatment for stroke patients with existing disability
This trial studies whether an endovascular (catheter-based) procedure to treat a certain type of blocked artery can improve outcomes for people who already had trouble functioning before their stroke. You may be considered if your stroke is confirmed early and your scans show the right type and location of blockage.
San Diego, CaliforniaAges 18 years+ - NCT06226805RecruitingPhase 2
Testing BB-031 for recent ischemic stroke
This study tests an experimental drug called BB-031 to see if it can safely help people who have had a recent ischemic stroke (a clot that blocks blood flow to the brain). The trial is for people who can get to the hospital within 24 hours of their first symptoms and have a moderate to severe stroke.
Burlingame, CaliforniaAges 18 years+ - NCT06440707RecruitingPhase 2
Brain stimulation for recent stroke recovery
This trial tests a safe, non-invasive brain stimulation technique called tDCS to help people recover from a recent stroke. It's for people who cannot have the standard clot-removal procedure and who can start treatment within 24 hours of their stroke.
Los Angeles, CaliforniaAges 18 years+ - NCT06961487Enrolling by invitation
Stroke treatment trial for large area brain damage
This trial tests if a procedure to remove a large blood clot from the brain (called a thrombectomy) can help people with severe strokes who have a large damaged area. It is for people who can be treated within 24 hours of their stroke starting.
Palo Alto, CaliforniaAges 18–90 - NCT06027788Recruiting
Embolic protection during heart valve surgery
This trial tests a device that may help protect your brain from small particles during heart valve surgery. It is for people 60 and older having certain types of valve replacement or repair.
Los Angeles, CaliforniaAges 60 years+ - NCT06029491Recruiting
Studying a new suction device for stroke treatment
This trial tests a new device that removes blood clots in the brain using suction. It is for people having a large-vessel ischemic stroke who can be treated within 8 hours of symptoms starting.
Torrance, CaliforniaAges 18–80 - NCT06990867RecruitingPhase 2/Phase 3
Improving blood flow recovery after stroke
This trial tests a new approach to restore blood flow in the brain after a stroke. It aims to improve recovery and brain function in people with a blocked large artery.
Sacramento, CaliforniaAges 18–90 - NCT05948566RecruitingPhase 2
Improving response to stroke treatment with an antibody drug
This Phase 2 trial tests an antibody treatment (TS23) given to people with a suspected acute ischemic stroke to improve how well they respond to stroke care. You may qualify if your stroke scan shows the right pattern of injured brain tissue and if the study drug can be given within a short time window after symptoms start.
La Jolla, CaliforniaAges 18 years+ - NCT06605014Recruiting
Body alignment after stroke or mini-stroke
This study looks at how a stroke or mini-stroke affects the body's natural movement and alignment (called somatic dysfunction). Researchers want to see if there are common patterns of tightness or imbalance after a stroke, which could help guide future treatments.
Sacramento, CaliforniaAges 18 years+ - NCT07614074Recruiting
Understanding Recovery from Coma and Unconsciousness
This study follows patients who have been in a coma (deep unconsciousness) for at least 24 hours due to a brain injury. Researchers will track how patients recover over time to better understand which factors help predict who will wake up and how well they'll recover.
San Francisco, CaliforniaAges 18 years+ - NCT06040255Enrolling by invitationPhase 4
Steroid treatment for focal brain artery inflammation in children
This trial tests whether short-term steroids improve recovery for children who recently had a stroke or mini-stroke caused by inflammation of a brain artery. If you qualify, you would receive steroids and follow-up imaging to see if it helps prevent further damage.
San Francisco, CaliforniaAges 1–18 - NCT04916210Recruiting
Study how stroke type affects thinking and recovery
This study looks at what predicts memory and thinking problems after different types of stroke or brain bleeding, and how blood-vessel changes relate to recovery. You may be invited if you recently had a stroke/bleed and can complete a baseline check within 6 weeks.
Los Angeles, CaliforniaAges 18 years+ - NCT06289985Recruiting
Expanding clot removal for medium vessel strokes
This trial tests a new approach to see if removing clots from medium-sized brain blood vessels can help more patients recover from stroke. It aims to expand the use of a standard clot-removal procedure to people with less severe symptoms or blockages in smaller vessels.
Stanford, CaliforniaAges 18 years+
Acute Ischemic Stroke trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting acute ischemic stroke studies listed above.
- University of California, Los Angeles (UCLA) · 8 studies
- Kaiser Permanente Los Angeles Medical Center · 5 studies
- University of California, San Francisco · 4 studies
- Adventist Health Glendale · 2 studies
- California Pacific Medical Center · 2 studies
- MemorialCare Long Beach Medical Center · 2 studies
- Stanford Cancer Institute · 2 studies
- Stanford University · 2 studies
What taking part in a acute ischemic stroke study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Acute Ischemic Stroke trials in other states
Common questions
- Are there acute ischemic stroke clinical trials in California?
- Yes. We're currently tracking 23 recruiting acute ischemic stroke studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a acute ischemic stroke study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a acute ischemic stroke trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New acute ischemic stroke studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.