Clinical trials
Acute Liver Failure clinical trials
Below are recruiting acute liver failure clinical trials, each written for real people, not researchers. We’re tracking 78 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07527156RecruitingPhase 4
Ketones through a nose tube for severe heart failure
This trial tests whether giving a special liquid diet (ketones) through a thin tube in your nose helps your heart pump better when it's severely weakened and not getting enough blood to your body. Ketones are an alternative fuel your body can use instead of glucose.
Prague, PragueAges 18 years+ - NCT04343430Recruiting
Hospital study for fluid buildup in heart failure with preserved heart function
This study looks at how well doctors can assess fluid buildup before you leave the hospital if you have a type of heart failure called “preserved ejection fraction.” It may help improve decisions about when and how safely people are discharged.
Vandœuvre-lès-NancyAges 18 years+ - NCT04343443Recruiting
Test whether a lung ultrasound helps discharge planning after heart failure
This study looks at people hospitalized for worsening heart failure with weaker pumping (reduced ejection fraction). It tests whether a lung ultrasound evaluation near discharge can improve how doctors decide it is safe to send you home.
Vandœuvre-lès-NancyAges 18 years+ - NCT07449377Recruiting
Can a liver scan help diagnose heart failure in the ER?
This study tests whether a quick, non-invasive liver scan (Fibroscan) can help diagnose heart failure in people who come to the emergency department with sudden shortness of breath.
ParisAges 18 years+ - NCT06173947Recruiting
SSM Score for Liver Injury in Chronic Liver Disease
This study looks at how well a simple score (called SSM) can predict recovery in people with chronic liver disease who suddenly get a liver injury with jaundice. It may help your doctors understand how serious your condition is.
Guangzhou, GuangdongAges 18–80 - NCT05744635Recruiting
Study tacrolimus levels after liver transplant
This non-interventional study looks at how tacrolimus blood levels relate to transplant effectiveness and side effects. It uses your existing medical data to understand whether tacrolimus behaves differently from person to person and how that links to safety.
BudapestAges 18 years+ - NCT05677100Recruiting
Aortix device for acute heart failure
This trial is testing a small pump placed in the aorta to help the kidneys remove extra fluid when standard IV diuretics aren't working well enough for severe heart failure. It may help you if you're hospitalized and still very congested (swollen, fluid buildup) despite strong water pills.
Phoenix, ArizonaAges 21 years+ - NCT05866796Recruiting
Test blood patterns to predict problems after liver transplant
This study checks whether a special blood test can predict who is at higher risk of graft loss (the transplanted liver not working well) and death after a liver transplant. It may help doctors identify higher-risk patients earlier and tailor follow-up care.
Ghent, FlandersAges 18 years+ - NCT06253104Recruiting
Tracking muscle changes in acute heart failure
This study measures how thigh muscles change in people hospitalized with severe heart failure. It aims to understand muscle loss during this condition and how it relates to recovery.
Boston, MassachusettsAges 18–100 - NCT06921603Recruiting
Ultrasound-guided diuretics for heart failure
This trial tests whether using a bedside ultrasound to guide diuretic treatment improves outcomes in people hospitalized for worsening heart failure. It may help find the right dose of IV diuretics faster.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06525623Recruiting
Early albumin for kidney injury in cirrhosis
This study tests whether giving a common fluid (albumin) early can help protect the kidneys in people with advanced liver disease who have a sudden kidney injury. It aims to see if this simple treatment can improve recovery and prevent the need for dialysis.
Boston, MassachusettsAges 18 years+ - NCT06285760Recruiting
Acetazolamide for fluid removal in acute heart failure
This study tests whether adding acetazolamide (a different type of water pill) to your current treatment helps remove extra fluid from your body more effectively when you are in the hospital for heart failure.
MadridAges Any age - NCT07149714Recruiting
Heart pump support for high-risk angioplasty
This trial tests the iVAC 2L device, a temporary heart pump placed in the main artery, to help patients who need a high-risk angioplasty (PCI) because of a very narrowed or blocked coronary artery. The goal is to prevent the heart from failing during the procedure.
MoscowAges 18 years+ - NCT04617522RecruitingPhase 1
Sacituzumab govitecan for advanced cancers with moderate liver issues
This Phase 1 study tests how safe and tolerable sacituzumab govitecan is for people with advanced or metastatic solid tumors who also have moderate liver impairment. It aims to find the right dosing so the treatment can be used more safely in this liver-risk group.
Long Beach, CaliforniaAges 18 years+ - NCT06286423RecruitingPhase 4
Colchicine for acute heart failure with low pumping strength
This trial tests if the anti-inflammatory drug colchicine can help people hospitalized with acute heart failure and a weak heart pump. It may benefit those with elevated inflammation markers.
Charlottesville, VirginiaAges 18 years+ - NCT05726032RecruitingPhase 2
Empagliflozin for fluid buildup from cirrhosis
This Phase 2 study tests empagliflozin to see if it can improve fluid buildup (ascites) in people with cirrhosis. It may help reduce symptoms related to fluid retention, but you must meet specific safety and stability requirements.
New Haven, ConnecticutAges 18 years+ - NCT07437755Recruiting
Guiding blood transfusions during procedures for cirrhosis
This study compares a special blood test (thrombelastometry) to standard tests to decide when to give blood products before invasive procedures in people with advanced liver cirrhosis. The goal is to see which method leads to better use of blood products and fewer complications.
Iași, IaşiAges 18 years+ - NCT06922669Recruiting
Steroids for drug-induced liver injury with high bilirubin
This trial tests whether steroids (glucocorticoids) can help people with acute liver injury caused by a drug, especially when bilirubin levels are high. It aims to see if steroids can reduce liver damage and improve recovery.
Shenyang, LiaoningAges 18–80 - NCT06994442RecruitingPhase 3
Best pain relief for children on a breathing tube
This study tests adding extra pain medicines (acetaminophen or an NSAID) to usual opioid pain treatment for children on a breathing machine. The goal is to find the safest and most effective way to manage pain.
Little Rock, ArkansasAges 2 months–17 years - NCT05759806Recruiting
Testing a device to treat fluid overload in heart failure
This trial studies a device (the Nephronyx System) used in the hospital to treat worsening heart failure with fluid buildup, especially when diuretics (water pills) aren’t working well. It aims to check the device’s safety and whether it performs as expected to help patients get better.
HaifaAges 18 years+ - NCT05346393Recruiting
TIPS procedure for kidney failure in people with cirrhosis
This trial studies whether a liver procedure called TIPS can help people with cirrhosis who develop sudden kidney failure (HRS-AKI). It aims to improve kidney function and overall outcomes, but participation depends on several safety checks.
AachenAges 18–80 - NCT06690684Enrolling by invitation
Finding new blood markers for heart disease
This study is looking for people who have had a heart attack or have heart failure to discover new markers in your blood that could help doctors better understand and treat heart disease. By collecting samples and health data, researchers hope to find clues that improve care for future patients.
Shanghai, Jing 'an DistrictAges 30 years+ - NCT03547232RecruitingPhase 4
Indomethacin given early to treat acute pancreatitis
This trial tests whether taking indomethacin (an anti-inflammatory medicine) early can improve outcomes in people with acute pancreatitis. You might be eligible if your pancreatitis is diagnosed soon and you meet specific lab, imaging, and safety requirements.
Beijing, Beijing MunicipalityAges 18–80 - NCT06937307RecruitingPhase 2
Droxidopa for low blood pressure in cirrhosis with kidney injury
This trial tests a medication called droxidopa to see if it can raise blood pressure in people with cirrhosis who also have acute kidney injury. If you have low blood pressure and are in the hospital with these conditions, this study may help improve your kidney function.
New York, New YorkAges 18–70
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Common questions
- Are there clinical trials for acute liver failure?
- Yes. Clin2 currently lists 78 recruiting acute liver failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute liver failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute liver failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.