Clinical trials
AD clinical trials
Below are recruiting ad clinical trials, each written for real people, not researchers. We’re tracking 314 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06203600RecruitingPhase 2/Phase 3
Nivolumab plus standard treatment for advanced stomach or esophageal cancer
This trial tests whether adding the immunotherapy drug nivolumab to standard treatment works better for advanced stomach or esophageal cancer. It is for people whose cancer has already progressed after a first round of chemo plus immunotherapy.
Little Rock, ArkansasAges 18 years+ - NCT06121544Recruiting
Pre-Alzheimer's Study: Find Early Brain Changes
This study is looking for healthy volunteers to help detect the very earliest signs of Alzheimer's disease—before memory loss starts. You will have tests like memory checks, blood draws, brain scans, and a spinal tap to look for Alzheimer's-related changes.
MalmöAges 50–80 - NCT05890352RecruitingPhase 2
Add new medicines to standard treatment for returning lymphoma
This Phase 2 study tests whether adding tafasitamab, lenalidomide, tazemetostat, and zanubrutinib (along with standard lymphoma treatment) can improve outcomes in people whose large B-cell lymphoma has returned or not responded. It may help control disease more effectively and improve response duration for eligible patients.
Tucson, ArizonaAges 18 years+ - NCT06090552Recruiting
Surgery planning help for adults 65+
This trial tests a program to help older adults plan their care before surgery. It may help you feel more prepared and supported through the process.
Irvine, CaliforniaAges 65 years+ - NCT06058377RecruitingPhase 3
Adding immunotherapy to chemo for stage II-III breast cancer
This trial tests whether adding the immunotherapy drug durvalumab to standard chemotherapy works better than chemo alone for people with hormone receptor positive, HER2 negative breast cancer that is stage II or III and has a high-risk genetic score (MammaPrint High Risk 2).
Birmingham, AlabamaAges 18 years+ - NCT06023407Enrolling by invitation
Heat therapy for blood sugar and Alzheimer's prevention
This study tests whether regular heat therapy (like sitting in a hot tub) can help improve blood sugar control and lower the risk of Alzheimer's disease in older women who have metabolic problems.
Kansas City, KansasAges 65 years+ - NCT05988385Recruiting
Treating sleep apnea to protect memory in older adults
This study tests whether treating sleep apnea can help protect memory and brain health in older adults. It involves using a CPAP machine or other treatments for sleep apnea and may include memory tests and brain scans over 2 years.
Tucson, ArizonaAges 55–85 - NCT05950607Recruiting
Nursing home study to reduce unnecessary antibiotic use
This study looks at ways to lower how often antibiotics are used in nursing home residents with Alzheimer’s disease and other dementias. It aims to make antibiotic use more appropriate while monitoring resident outcomes.
Boston, MassachusettsAges 60–106 - NCT05925309Recruiting
Oral antibiotics to prevent bile duct inflammation after Kasai surgery
This trial studies whether giving oral antibiotics before symptoms start can lower the chance of cholangitis (bile duct infection/inflammation) after Kasai portoenterostomy. It may help protect your child’s bile flow and reduce painful or serious infections after surgery.
Shanghai, Shanghai MunicipalityAges 2 weeks–3 months - NCT04702256RecruitingPhase 3
Treating lupus kidney inflammation with or without extra steroid tablets
This trial tests whether adding standard oral steroid tablets to mycophenolate helps lupus nephritis (inflammation of the kidneys) more than using obinutuzumab plus mycophenolate, without extra oral steroids. It may help find a treatment plan that controls active kidney disease while changing how much steroid is used.
ParisAges 14 years+ - NCT05887167RecruitingPhase 1
Test safety of making CAR T cells from your own blood
This Phase 1 study looks at whether it is safe and practical to collect your own stem cells and use them to support CAR T-cell therapy for certain blood cancers that have come back or did not respond. It aims to find the best way to combine these steps, which may help some people receive CAR T treatment.
Los Angeles, CaliforniaAges 18–85 - NCT05907343Recruiting
Brain stimulation study for memory and thinking concerns
This study tests a new brain stimulation method that may help improve memory and thinking in older adults who have memory concerns. It uses a safe, non-invasive technique called transcranial magnetic stimulation (TMS) that sends magnetic pulses to the brain.
Austin, TexasAges 18–90 - NCT05881239Recruiting
Remote smell tests to track early Alzheimer’s health changes
This trial uses remote, at-home (or remote) smell-based testing to help researchers assess health in people with preclinical Alzheimer’s disease and in control participants. It may help by showing how well smell-related changes can signal disease status over time.
Boston, MassachusettsAges 18–100 - NCT05851924RecruitingPhase 2
Nalirifox plus radiation for nonmetastatic pancreatic cancer
This trial studies Nalirifox (chemotherapy) given together with radiation therapy for pancreatic ductal adenocarcinoma that has not spread to distant organs. It may help shrink the cancer and improve local control, especially when surgery is not an option right now.
Basking Ridge, New JerseyAges 18 years+ - NCT05842161Recruiting
Smoking cessation program for people with HIV and TB in South Africa
This study is testing a program to help people who are living with HIV and TB to stop smoking. It aims to see if quitting smoking improves their engagement with HIV and TB care.
RondeboschAges 18 years+ - NCT05814640RecruitingPhase 1/Phase 2
STAR-AD: Testing stepwise treatment for teen depression
This trial tests a step-by-step approach to treating moderate-to-severe depression in teens. It may help find a treatment path that improves mood while keeping care safe, including for some teens who have suicidal thoughts but do not need inpatient care.
Chongqing, ProvinceAges 13–18 - NCT05782582Recruiting
Testing care for long-term heart artery symptoms in primary care
This study looks at people who come to primary care with symptoms that may be caused by long-term narrowing of heart arteries. The goal is to test an approach for identifying and managing this condition earlier or more accurately in everyday care.
LinköpingAges 18 years+ - NCT05772845Recruiting
Study of quitting support for vaping and smoking withdrawal
This study looks at nicotine withdrawal symptoms in people who vape and/or smoke regularly. It may help improve how quitting support is tailored, based on how participants respond during the withdrawal period.
Buffalo, New YorkAges 21–50 - NCT05718323RecruitingPhase 2
Niraparib with immunotherapy maintenance for advanced small-cell lung cancer
This trial tests whether adding niraparib (a pill cancer medicine) to ongoing immunotherapy maintenance can help people with advanced small-cell lung cancer live longer or better. It is for tumors that show a specific protein marker (SLFN11) and that did not worsen after standard first-line chemo-immunotherapy.
AngersAges 18 years+ - NCT05669339RecruitingPhase 2
AI-guided dosing study for advanced liver cancer patients
This Phase 2 study tests whether an artificial intelligence tool can help doctors choose the right dose for treating advanced hepatocellular carcinoma (HCC), a type of liver cancer. It aims to improve safety and effectiveness by matching treatment to you using your liver function, lab results, and treatment course.
Gainesville, FloridaAges 18–99 - NCT05592678Recruiting
Study brain and memory test changes in Alzheimer’s or mild issues
This study looks at how well people with Alzheimer’s disease (AD) or mild cognitive impairment (MCI) perform on standardized memory/brain tests. It may help researchers understand changes over time, and whether certain types of brain signals or test results track with the condition.
San Antonio, TexasAges 65–100 - NCT05606341RecruitingPhase 1
Testing a diabetes-style shot to boost brain immunity in early Alzheimer’s
This Phase 1 study tests whether stimulating the immune system (through a receptor called TLR9) is safe and may affect brain changes in people with early Alzheimer’s. It mainly enrolls older adults with memory impairment confirmed by specific amyloid imaging.
New York, New YorkAges 60–85 - NCT05626374Enrolling by invitation
Remote check-in tool to reduce dropout in training
This study tests whether adding a remote, self-report tool for distress (how overwhelmed or unwell someone feels) improves how many people complete a vocational training program. It’s meant to support people using the usual case management, but with extra remote check-ins.
Barrie, OntarioAges 18–49 - NCT05584826RecruitingPhase 2
MDMA therapy for cancer patients and their partner’s distress
This Phase 2 study tests whether MDMA-assisted therapy can reduce adjustment-related distress in cancer patients who are paired with a loved one who is also concerned. It may help the patient and their significant other cope better through structured therapy sessions, with safety checks before and after each session.
Rockville, MarylandAges 18 years+
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Common questions
- Are there clinical trials for ad?
- Yes. Clin2 currently lists 314 recruiting ad studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ad trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ad trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.