Clinical trials
Adult clinical trials
Below are recruiting adult clinical trials, each written for real people, not researchers. We’re tracking 3,742 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05768139RecruitingPhase 1/Phase 2
Testing a new targeted drug for advanced solid tumors with PI3Kα mutation
This trial tests tersolisib, a new targeted medicine, in adults with advanced or hard-to-remove solid cancers. It focuses on tumors that have a specific genetic change (PI3Kα mutation) to see how well the treatment works and what side effects it causes.
Los Angeles, CaliforniaAges 18 years+ - NCT05768178RecruitingPhase 2/Phase 3
Vemurafenib plus cobimetinib for BRAF-mutant cancers
This trial tests whether combining two targeted cancer medicines—vemurafenib and cobimetinib—can treat adults whose tumors have a specific “BRAF V600” mutation. You may be screened with blood tests and a tissue biopsy before starting treatment.
BelfastAges 18 years+ - NCT05771844Recruiting
Home sleep treatment for older adults with memory changes
This study tests whether a home sleep therapy program can improve symptoms in older adults who have amnestic mild cognitive impairment (MCI) or help compare to people without MCI. It may be useful if your main issue is memory or thinking changes and you also have sleep problems.
Winston-Salem, North CarolinaAges 40–85 - NCT05772559Recruiting
Study of AML genes and drug response in young patients
This trial looks at how childhood, teen, and young adult acute myeloid leukemia (AML) changes at the genetic level and how cells respond to multiple drugs. It may help doctors understand which treatments work best and how leukemia interacts with supportive cells in the bone marrow.
AmiensAges Up to 25 years - NCT05773040RecruitingPhase 1
CAR T-cell therapy made from your own immune cells
This Phase 1 trial tests an “autologous” CAR T-cell treatment (made from your own T cells) that targets a cancer marker called CD79b in certain relapsed or hard-to-treat B-cell lymphomas. It’s designed to find a safe dose and see whether the treatment can shrink tumors and help control the lymphoma after prior therapies.
Houston, TexasAges 18 years+ - NCT05779917RecruitingPhase 1
CAR-T cells for cancers that have specific target proteins
This Phase 1 trial tests a customized immune therapy (CAR-T cells) for advanced cancers that have the proteins mesothelin, GPC3, and/or GUCY2C. It may help your body better recognize and kill cancer cells, but early-phase trials mainly focus on safety and learning how well the treatment works.
Guangzhou, GuangdongAges 18–75 - NCT05783609RecruitingPhase 2
Epcoritamab and rituximab for untreated follicular lymphoma
This phase 2 trial tests whether a combination of epcoritamab plus rituximab can work as a first treatment for follicular lymphoma. It may help people whose lymphoma is causing symptoms or affecting organs, or who have bulky disease, by targeting the lymphoma cells.
Boston, MassachusettsAges 18 years+ - NCT05785533Recruiting
Mobile app for recovery after recent ankle sprains
This trial tests whether a smartphone “recovery guidance” app can help children and young adults heal after a recent ankle inversion injury. It may help with home recovery steps and decision-making during the first days after injury.
London, OntarioAges 12–30 - NCT05786417RecruitingPhase 4
Medication comparison for older adults with stable heart pain
This trial tests which heart medications work best for older adults who have stable angina (predictable chest pain) and multiple other long-term health problems. You may be asked to start or adjust medications and attend regular follow-up visits to see which approach controls symptoms and outcomes.
New Haven, ConnecticutAges 65 years+ - NCT05788666Recruiting
GeriKit check-up for older adults after heart artery problems
This trial tests a “GeriKit” set of questions and measurements to better understand health and needs in people age 75+ after a heart attack or related procedures. It may help doctors plan more personalized care during recovery.
New York, New YorkAges 75–100 - NCT05786898Recruiting
Test a computer training program to improve autism-related thinking
This study tests a computerized “cognitive remediation” program adapted for people with autism, using social scenarios and skills. The goal is to improve thinking and related day-to-day abilities by practicing structured tasks on a screen.
ParisAges 13–40 - NCT05790720Recruiting
Propofol dosing study for older adults
This study looks at how the anesthetic drug propofol works in older adults during planned surgeries. The goal is to find the right dose for safe and effective anesthesia.
Santiago, Santiago MetropolitanAges 65–99 - NCT05802004Recruiting
Sound stimulation to improve sleep and emotions in young adults
This study tests whether gentle sound stimulation during sleep can improve sleep and how you think and feel in daily life when you have anxiety or depression symptoms. You’ll also do sleep testing in a lab and complete questionnaires to measure changes.
Pittsburgh, PennsylvaniaAges 18–25 - NCT05814822Recruiting
CBT for sleep problems in adults using cannabis
This study looks at a sleep-focused treatment to help adults who have ongoing insomnia and also use cannabis regularly. If sleep improves, the trial hopes it may also improve overall outcomes for cannabis use.
Ann Arbor, MichiganAges 21 years+ - NCT05817734Recruiting
Research study to collect health information from adults
This is a research study that collects information about your health and traits to better understand human health and variation. It is mainly for adults who can consent and do not have several specific medical situations listed below.
RehovotAges 18 years+ - NCT05819853RecruitingPhase 3
Semaglutide to help restart periods in PCOS
This Phase 3 study tests whether semaglutide can help people with polycystic ovary syndrome (PCOS) start ovulating and having more regular periods. You may join with or without metformin, and contraception rules are important because the medicine must not be used during pregnancy.
Aurora, ColoradoAges 12–35 - NCT05819476Recruiting
Testing how open-label placebos affect induced pain
This study tests whether people can feel less pain when they know they are receiving a “placebo” (a treatment with no active pain-relieving medicine). It’s done in healthy adults by triggering short-lasting pain in a controlled way to see how the placebo effect changes pain feelings.
BaselAges 18–65 - NCT05825989Recruiting
Healthy beat acupressure for older adults’ fitness at home
This trial studies whether a “healthy beat” acupressure-like technique (healthy beat acupunch) can improve physical fitness in older adults living in residential homes. It may help people who are able to exercise safely but want to improve strength, movement, and overall fitness.
Bang Khae, BangkokAges 65 years+ - NCT05827406Recruiting
Support system for psychiatric checkups in adults
This study looks at a helpful support system to improve how psychiatric symptoms are diagnosed and followed over time. It may help patients and clinicians by making checkups and next steps more organized.
StockholmAges 18 years+ - NCT05828511RecruitingPhase 1/Phase 2
Study drug for newly diagnosed myeloma before standard treatment
This trial tests linvoseltamab (a new targeted immune treatment) to see if it’s safe and how well it works in adults with recently diagnosed multiple myeloma who haven’t started treatment yet. Because it’s a “window of opportunity” study, it’s meant to learn early results before standard therapy is fully underway.
Los Angeles, CaliforniaAges 18 years+ - NCT05829070Recruiting
Helps young adult cancer survivors understand health insurance
This study tests a program to improve health insurance know-how for young people who have finished cancer treatment. It may help you navigate coverage, costs, and benefits more confidently after cancer.
Murray, UtahAges 26–45 - NCT05830942Recruiting
Training walks plus brain stimulation for thinking skills in older adults
This study tests whether a structured walking exercise, combined with brain stimulation and brain scans, can improve or slow decline in thinking skills. It’s aimed at older adults who notice memory or confusion getting worse.
Gainesville, FloridaAges 65 years+ - NCT05835479RecruitingPhase 2
Rezafungin to treat Pneumocystis pneumonia in adults with HIV
This Phase 2 trial tests rezafungin, an antifungal medicine, to treat Pneumocystis pneumonia (PCP) in adults living with HIV. It may help people recover faster or more effectively from this serious lung infection.
Cape TownAges 18 years+ - NCT05836259RecruitingPhase 1/Phase 2
TN-201 for heart symptoms from MYBPC3 heart disease
This early trial tests TN-201 to see how safe it is and how well it works to reduce symptoms in adults with MYBPC3-related hypertrophic cardiomyopathy. It’s designed to learn safe dosing, and you may be eligible if you have specific genetic heart changes and ongoing symptoms.
La Jolla, CaliforniaAges 18–75
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Common questions
- Are there clinical trials for adult?
- Yes. Clin2 currently lists 3,742 recruiting adult studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a adult trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a adult trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.