Clinical trials
Advanced or Metastatic Non-small Cell Lung Cancer clinical trials
Below are recruiting advanced or metastatic non-small cell lung cancer clinical trials, each written for real people, not researchers. We’re tracking 5,550 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05868876RecruitingPhase 1
Testing AK127 plus AK104 for advanced cancers
This Phase 1 study tests the safety and early anti-cancer activity of AK127 given together with AK104 in people with advanced solid tumors. You may be considered if standard treatments have already been tried or aren’t suitable for you.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT05852522Recruiting
Testing treatment planning to help eradicate rare advanced cancers
This trial looks at a more tailored way to choose treatment for people with rare cancers that have spread or grown locally and can’t be cured with standard therapies. The goal is to better target the tumor to improve the chance of tumor shrinkage or eradication.
HeidelbergAges 18 years+ - NCT07349784Recruiting
Automated lung opening steps during laparoscopic surgery
This trial tests a computer-controlled method to open collapsed lung parts during laparoscopic colorectal cancer surgery. It aims to improve breathing and reduce complications after surgery.
Istanbul, BakırkoyAges 18–80 - NCT07346846RecruitingPhase 1
Testing BGM-2121 for advanced solid tumors
This study tests an experimental drug called BGM-2121 for people with advanced solid tumors that have not responded to or stopped responding to standard treatments. The goal is to see if the drug is safe and if it can shrink tumors.
TainanAges 18 years+ - NCT07348653RecruitingPhase 1
Study of MG2512 for advanced solid tumor patients
This trial tests a new drug called MG2512 for people with advanced solid tumors that have not responded to standard treatments or who cannot take standard therapy. The study aims to understand if MG2512 is safe and effective.
Beijing, Beijing MunicipalityAges 18–75 - NCT06443489RecruitingPhase 1
SHR-4849 for advanced solid tumors
This trial tests a new drug called SHR-4849 for people with advanced solid tumors that have not responded to other treatments. It aims to see if the drug is safe and effective, and may offer a new option for those who have limited choices.
Jilin City, ChangchunAges 18–75 - NCT07338838RecruitingPhase 1
Testing TQB3142 in advanced tumors
This trial tests a new drug called TQB3142 in people with advanced cancers that have not responded to standard treatments. The goal is to find a safe dose and see how the drug works in the body.
Guangzhou, GuangdongAges 18–75 - NCT07340190RecruitingPhase 1
How pelabresib affects other drugs in advanced cancer
This study tests how a new drug (pelabresib) interacts with other medicines like diabetes pills, a sedative, and birth control pills. It is for people with advanced cancer to help understand safe dosing.
BordeauxAges 18 years+ - NCT07337850Recruiting
Testing 68Ga-FAPI PET scan in biliary cancers
This trial is testing a new type of PET scan (called 68Ga-FAPI) to see if it can better detect biliary tract cancers, including advanced or recurring gallbladder cancer and intrahepatic cholangiocarcinoma. It may help doctors find cancer more accurately, which could guide better treatment decisions.
Mumbai, MaharashtraAges 18–90 - NCT07326488RecruitingPhase 1/Phase 2
Study of MHB009C for advanced solid tumors
This trial tests a new drug called MHB009C for people with advanced solid tumors that have not responded to other treatments. The goal is to see if the drug is safe and effective.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07328217RecruitingPhase 1/Phase 2
Study of GW5282 for advanced solid tumors
This trial tests a new oral drug, GW5282, for people with advanced solid tumors that have stopped responding to standard treatments. The goal is to see if this drug can shrink tumors or stop them from growing.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07331155RecruitingPhase 2
LBL-024 combo for advanced esophageal cancer
This trial tests a new drug combination for advanced solid tumors, specifically esophageal cancer. It may help people whose cancer has not responded to other treatments.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07333053Recruiting
Chemotherapy through a catheter for advanced colorectal cancer
This trial tests giving chemotherapy directly into the artery that feeds the tumor, which may help control advanced colorectal cancer that cannot be removed with surgery. It is for people who have not yet had other treatments and whose main tumor is in the colon or rectum.
Xicheng, Beijing MunicipalityAges 18 years+ - NCT07321574RecruitingPhase 2
Testing ABP1011T for advanced solid tumors
This trial tests an experimental pill called ABP1011T for people with advanced solid tumors that are no longer responding to standard treatments. It is especially focused on small cell lung cancer and other cancers that might be sensitive to this drug. The goal is to see if the pill can shrink tumors or slow their growth.
Luoyang, HenanAges 18–75 - NCT06863090Recruiting
Study measuring radiation dose during brachytherapy
This trial tests a way to measure the exact radiation dose you receive during internal radiotherapy (brachytherapy). It aims to make treatment safer and more effective for prostate or gynecologic cancers.
Northwood, MiddlesexAges 18 years+ - NCT07323745RecruitingEarly Phase 1
Mobithron Advance for knee osteoarthritis: long-term effects
This trial tests a supplement called Mobithron Advance to see if it can slow down knee osteoarthritis over time. It may help people with mild to moderate knee arthritis find a non-surgical option.
Kota Bharu, KelantanAges 50 years+ - NCT05142423RecruitingPhase 1/Phase 2
First study of AK109 plus AK104 for advanced solid cancers
This Phase 1/2 trial tests a combination of two immune-targeting drugs (AK109 and AK104) in people with advanced solid tumors that can’t be treated with standard options, or where standard treatment didn’t work or wasn’t tolerated. It aims to find safe dosing and whether the treatment can shrink tumors or control the disease.
Hangzhou, ZhejiangAges 18–75 - NCT06035679Recruiting
Combination therapy before surgery for HER2-positive breast cancer
This trial tests a combination of targeted therapies and chemotherapy given before surgery for HER2-positive breast cancer. It aims to see if this approach helps shrink tumors and improve outcomes.
Fuzhou, FujianAges 18–75 - NCT06030947Recruiting
Micro graft for treating multiple gum recessions
This trial tests a new micro connective tissue graft to cover multiple areas where your gums have pulled away from your teeth (recession). It may help if you have healthy gums but several receding spots on your upper or lower jaw.
DubaiAges 18–60 - NCT07310134RecruitingPhase 1
Study of ZX-8177 for advanced solid tumors
This trial tests a new oral drug (ZX-8177) for people with advanced solid tumors that have stopped responding to standard treatments or cannot be treated with standard options. The goal is to see if it is safe and helps control the disease.
ShanghaiAges 18 years+ - NCT07310784RecruitingPhase 2
Testing LM103 for advanced melanoma
This trial tests a new drug called LM103 for people with advanced melanoma who have already tried several standard treatments, including immunotherapy. The goal is to see if LM103 can help shrink tumors when other treatments have stopped working.
Beijing, Beijing MunicipalityAges 18–75 - NCT07309562RecruitingPhase 3
Growth hormone trial for short children born small
This study tests an experimental growth hormone (Inpegsomatropin) to help children born small for gestational age who remain short. If your child meets the specific height, age, and puberty criteria, they may qualify.
BeijingAges 2–11 - NCT07315347Recruiting
Treating blood clots in the lung at home for cancer patients
This study tests whether people with active cancer and a new blood clot in the lung can be safely treated at home instead of in the hospital. If you have cancer and a blood clot that is not causing severe symptoms, you may be able to join this trial.
Colombes, FranceAges 18 years+ - NCT07313241RecruitingPhase 2
Salvage radiation with hormone therapy for prostate cancer recurrence
This trial tests how well salvage radiation therapy works for prostate cancer that has come back after surgery. It looks at whether adding hormone therapy based on PSA response improves outcomes.
Dallas, TexasAges 18 years+
Hear when a new Advanced or Metastatic Non-small Cell Lung Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for advanced or metastatic non-small cell lung cancer?
- Yes. Clin2 currently lists 5,550 recruiting advanced or metastatic non-small cell lung cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a advanced or metastatic non-small cell lung cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a advanced or metastatic non-small cell lung cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Locally Advanced or Metastatic Non-small Cell Lung Cancer
- Metastatic Non-squamous Non Small Cell Lung Cancer
- Advanced Non-squamous Non-small-cell Lung Cancer
- NSCLC (Advanced Non-small Cell Lung Cancer)
- Non Small Cell Lung Cancer Metastatic
- Non Small Cell Lung Cancer
- Non-squamous Non-small Cell Lung Cancer
- Locally Advanced Non-Small Cell Lung Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.