Clinical trials
Advanced clinical trials
Below are recruiting advanced clinical trials, each written for real people, not researchers. We’re tracking 3,908 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07743918Recruiting
Vitamin D and outcomes in locally advanced cervical cancer
This study looks at how vitamin D levels affect treatment results in women with locally advanced cervical cancer who are about to start chemoradiation (chemotherapy plus radiation). It aims to see if higher vitamin D is linked to better outcomes.
Kragujevac, ŠumadijaAges 18–80 - NCT06615193RecruitingPhase 1
Testing a new drug for certain blood and solid tumors
This study tests a new drug, HDM2005, for people with relapsed or hard-to-treat B-cell lymphoma or advanced solid tumors. The goal is to see if it is safe and effective.
Zhengzhou, HenanAges 18 years+ - NCT07737509Recruiting
Understanding genetic factors in advanced solid tumor treatment
This study collects and analyzes tumor samples from people with advanced solid cancers to understand why some treatments work better than others and why resistance can develop. It aims to improve future treatments for patients like you.
SuttonAges 18 years+ - NCT07732491RecruitingPhase 2
Culmerciclib for HR+ HER2+ advanced breast cancer
This study tests a new drug called Culmerciclib for women with a certain type of advanced breast cancer that has both hormone receptors and HER2. It’s for patients whose cancer has been stable on at least 4 cycles of prior therapy.
Guangzhou, GuangdongAges 18 years+ - NCT07733180RecruitingPhase 2
Study of tislelizumab plus chemo for advanced esophageal cancer
This trial tests different schedules of tislelizumab (an immunotherapy drug) combined with chemotherapy for Japanese patients with advanced esophageal squamous cell carcinoma that cannot be removed by surgery or has spread. It aims to find a better way to give these treatments together.
Yokohama, KanagawaAges 18 years+ - NCT05594095RecruitingPhase 2
Study for advanced ER+ HER2− breast cancer after CDK4/6 therapy
This Phase 2 trial tests an investigational “SNF platform” treatment for advanced ER+ (estrogen-receptor positive) and HER2− breast cancer in people who already tried CDK4/6 inhibitor therapy. It may help shrink tumors and improve outcomes for cancers that have come back or spread.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06624098Recruiting
Early TIPS for Advanced Liver Cancer with Vein Blockage
This study tests whether placing a small tube (TIPS) early in people with advanced liver cancer and a vein blockage helps their other treatments work better. It is for patients who are already taking lenvatinib and immunotherapy.
Beijing, Beijing MunicipalityAges 18–75 - NCT07730190RecruitingPhase 1
Study of TQB6426 for advanced solid tumors
This study tests an investigational drug called TQB6426 for people with advanced solid tumors that have not responded to standard treatments. The drug targets a protein called GPC3 found on some tumor cells. The goal is to see if the drug is safe and effective.
Hefei, AnhuiAges 18–75 - NCT07723482RecruitingPhase 1/Phase 2
Study of ML-016 for cancer that has spread to lungs or liver
This trial tests a new drug called ML-016 in people whose advanced cancer has spread to their lungs or liver and who have run out of standard treatment options. The goal is to see if ML-016 can shrink tumors or slow the cancer's growth.
Miranda, New South WalesAges 18 years+ - NCT07719920RecruitingPhase 1
Study of HW221043 for advanced solid tumors
This trial is testing a new oral drug called HW221043 for people with advanced solid tumors that have not responded to other treatments. The goal is to see if it is safe and how well it works.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06632574RecruitingPhase 1
Paclitaxel liposomes via artery for advanced solid tumors
This trial tests a new form of paclitaxel (a chemotherapy drug) wrapped in tiny fat bubbles called liposomes. It is given directly into an artery that feeds the tumor, which may deliver the drug more effectively to the cancer. The study is for people with advanced solid tumors that can be treated this way, such as stomach, liver, pancreatic, or lung cancers.
NanjingAges 18 years+ - NCT07721792Recruiting
Study on advanced braces for leg injuries
This study tests a new type of leg brace for people who currently use an ankle-foot orthosis (AFO) to help with walking or daily activities after a lower leg injury. The goal is to see if the new brace works better and is more comfortable.
Tampa, FloridaAges 18–80 - NCT07721116Recruiting
AI Study of Knee Imaging and Treatment Results
This study uses artificial intelligence (AI) to better understand knee images from healthy people and those with knee arthritis. It aims to predict how well knee injections might work for you.
Taipei, TaiwanAges 18 years+ - NCT07713550Recruiting
Genetic profiling to guide treatment for advanced solid tumors
This study tests whether analyzing the DNA of your tumor (from a tissue sample or blood draw) can help find the best treatment for your advanced cancer. Researchers will look for genetic changes that could make you eligible for targeted therapy or a clinical trial.
AnderlechtAges 18 years+ - NCT07708870Recruiting
Nurse-led support for older adults with advanced lung cancer
This study tests a nurse-led support program for older adults (65+) with advanced lung cancer and their main family caregiver. The goal is to see if special help from a nurse can improve quality of life for both you and your caregiver.
Taipei, TaipeiAges 18 years+ - NCT07712029RecruitingPhase 2
A new drug combo for EGFR positive advanced solid tumors
This trial tests a new combination of two drugs—Becotatug Vedotin (a targeted therapy that delivers chemotherapy directly to EGFR-positive cancer cells) and Pucotenlimab (an immunotherapy that helps your immune system fight cancer). It is for people with advanced solid tumors that have not responded to standard treatments.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT04387916RecruitingPhase 1
Test drug KC1036 in people with advanced solid tumors
This Phase 1 trial studies how a new medicine (KC1036) works and how safe it is for people with advanced solid cancers that have grown despite standard treatments. It may help future patients by showing whether the drug can control cancer in difficult-to-treat cases.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT04093466RecruitingPhase 1
Testing a new pill for advanced solid tumors
This Phase 1 trial tests kanitinib (CX1003), a new cancer medicine, in people with advanced solid tumors that have come back or stopped responding to standard treatment. The goal is to find a safe dose and see early signs of tumor response.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07702162RecruitingPhase 1
Testing PA5 in advanced solid tumors
This trial tests a new drug called PA5 for people with advanced solid tumors that no longer respond to standard treatments. The goal is to see if PA5 is safe and how well it works against these cancers.
Fuzhou, FujianAges 18 years+ - NCT07700160RecruitingPhase 1/Phase 2
Testing a new drug for advanced solid tumors
This trial tests an experimental drug called VBC108 in people with advanced solid tumors that have not responded to other treatments. The study aims to see if the drug is safe and effective.
Duarte, CaliforniaAges 18 years+ - NCT07704658RecruitingPhase 4
Pralsetinib drug interaction study for advanced solid tumors
This trial tests how pralsetinib interacts with other drugs in people with advanced solid tumors that have a specific RET gene change. It aims to find the right dose and safety profile.
Logroño, La RiojaAges 18 years+ - NCT07697937RecruitingPhase 2
YH02 injection for advanced solid tumors that didn't respond to treatment
This trial tests a new injection, YH02, directly into tumors for people with advanced solid tumors (like head and neck, breast, or melanoma) that are no longer responding to standard treatments. The goal is to see if it can shrink tumors or slow disease progression.
TianjinAges 18 years+ - NCT07698964Recruiting
CARE: A program to build resilience and heart health
This study tests a program called CARE designed to help women manage stress and reduce heart disease risk. Participants will learn skills to build resilience and improve their overall well-being.
Edinburg, TexasAges 18–49 - NCT07703163RecruitingPhase 1
Canagliflozin for advanced solid tumors in patients with or without diabetes
This trial tests canagliflozin, a diabetes drug, combined with immunotherapy for people with advanced solid tumors. It may help if you have type 2 diabetes or are at risk, but you don't need diabetes to join.
Chengdu, SichuanAges 18–80
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Common questions
- Are there clinical trials for advanced?
- Yes. Clin2 currently lists 3,908 recruiting advanced studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a advanced trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a advanced trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.