Clinical trials
Alcohol Use Disorder clinical trials
Below are recruiting alcohol use disorder clinical trials, each written for real people, not researchers. We’re tracking 370 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06793488RecruitingEarly Phase 1
Anxiety and alcohol use disorder treatment study
This study tests whether a medication called disulfiram (Antabuse) can help people with alcohol use disorder (AUD) feel less anxious when they stop drinking. Researchers will also use brain scans (MRI) to look at how the brain changes during early abstinence.
New York, New YorkAges 21–55 - NCT06853314Recruiting
PrEP for women with past legal or child welfare involvement
This trial tests a program to help women who have had contact with the criminal legal system or child protective services get and stay on PrEP (a daily pill that prevents HIV). The study also looks at how to support women who have experienced intimate partner violence or risky drinking.
New York, New YorkAges 18 years+ - NCT06864819Recruiting
Alcohol blood test and surgery recovery study
This study looks at a blood test called phosphatidylethanol (PEth) to see if it can help predict how well you recover after surgery. It is for people who drink alcohol regularly and are having elective surgery with a longer hospital stay or ICU stay at University Hospitals Cleveland Medical Center.
Cleveland, OhioAges 21–79 - NCT07052318Recruiting
Music app for stress relief in early alcohol recovery
This study tests whether listening to music through a smartphone app can help reduce stress for people who are in the first year of recovery from alcohol use disorder. If you're 18-35 and have a smartphone, you may be able to join.
Spokane, WashingtonAges 18–35 - NCT07217795Recruiting
Recovery group for LGBTQ+ mental health and substance use
This trial is testing a new type of talk therapy program designed to help sexual minority women and transgender/gender diverse people recover from mental health and substance use challenges. It focuses on learning coping skills, building self-confidence, solving problems, and finding community support.
Providence, Rhode IslandAges 18 years+ - NCT07269119Recruiting
Pilot study of a Deaf-friendly alcohol treatment
This study tests a new way to help Deaf adults who use ASL and have problem drinking. It is done over Zoom and is designed to be accessible.
Shrewsbury, MassachusettsAges 18 years+ - NCT07341230Recruiting
Deep brain stimulation for alcohol addiction
This trial tests if deep brain stimulation can help people with severe alcohol addiction who haven't been helped by other treatments. It involves implanting a device to stimulate brain areas linked to addiction.
Cambridge, CambridgeshireAges 18–60 - NCT02037867Recruiting
Study your liver blood markers if you’re at risk
This study looks at how certain blood tests (liver biomarkers) change in people with higher risk for liver disease. It may help doctors understand who is developing liver problems earlier and what patterns in blood tests matter most.
Nottingham, NottsAges 18 years+ - NCT06290778Enrolling by invitation
Mental health prevention training for fire fighter trainees
This study tests a program where peers teach emotion regulation skills to help prevent mental health issues in new fire fighters. You would be asked to complete surveys and attend training sessions.
Waco, TexasAges 21 years+ - NCT05947539Enrolling by invitation
Helping Ugandan young women stay engaged in HIV care
This study tests a couples-focused program to help HIV-positive adolescent girls and young women stay connected to HIV clinic visits and medicines. It may help if you’re currently not well engaged in HIV care or you’ve faced partner violence or controlling behavior.
KampalaAges 15 years+ - NCT04043442Enrolling by invitationPhase 2
Brain stimulation study for alcohol use with mild brain injury
This trial tests a type of brain stimulation to help with day-to-day functioning in people who have alcohol use disorder and a history of mild traumatic brain injury. It also uses brain and symptom testing to see who may benefit most and why.
Hines, IllinoisAges 22–65 - NCT06319885Recruiting
Text messaging to reduce high-risk alcohol use in older adults
This study uses text messages to help adults aged 55–80 who drink above recommended limits to reduce their alcohol intake. If you want to cut back but not necessarily quit completely, this program may be a good fit for you.
Odense, Southern DenmarkAges 55–80 - NCT07184983Recruiting
Brain stimulation for cannabis use disorder
This study tests whether a gentle brain stimulation technique (called tDCS) can help people who want to cut down or stop using cannabis. You'll wear a headband-like device during sessions at NYU, and the study team will check in with you over time.
New York, New YorkAges 22–65 - NCT07447635Recruiting
Testing a program to help cancer survivors quit smoking and reduce drinking
This study tests a program (MBI) to help cancer survivors quit smoking and cut back on alcohol. It's designed for people who want to make these changes in the next 30 days.
Tampa, FloridaAges 18 years+ - NCT04164940Recruiting
Tracking how hospital care affects alcohol risk in older adults
This study looks at how adults aged 21+ change over time after being admitted to the hospital for alcohol-related problems. It may help researchers understand which hospital approaches work best for reducing future alcohol-related harm—especially for people who have not had alcohol or drug use disorders before.
StavangerAges 21 years+ - NCT01730781Recruiting
PET scan study to image cannabinoid receptors in the brain
This study uses a special brain scan (PET) to measure cannabinoid receptors—areas in the brain that interact with cannabis-like chemicals. It may help researchers better understand how these receptors relate to conditions such as schizophrenia, PTSD, opioid use disorder, or early psychosis risk.
New Haven, ConnecticutAges 18–55 - NCT05538910Recruiting
Study brain links between depression and substance use
This study uses brain imaging and questionnaires to understand how substance use and depression are connected in the brain. It may help researchers identify biological patterns that could guide better treatments in the future.
Baltimore, MarylandAges 18–60 - NCT04395196RecruitingPhase 2
Prenatal choline for pregnancy after alcohol exposure
This trial tests whether taking a choline supplement during pregnancy can reduce harmful effects on the baby when a person drinks heavily while pregnant. It may help support healthier pregnancy and baby outcomes for those who meet the study’s drinking and nutrition criteria.
Cape Town, Western CapeAges 18–45 - NCT05910580Recruiting
Screening and support for alcohol and substance risk in adults
This study aims to improve care access and outcomes for adults who screen positive for risky alcohol or drug use. If you qualify, you may be offered ways to connect to support during your reproductive years.
Boston, MassachusettsAges 18 years+ - NCT04721418Recruiting
Imaging brain changes in cocaine use or health controls
This study uses a brain scan to look at changes in brain connections in people with cocaine use disorder, and compares them with healthy volunteers. It may help researchers understand how cocaine affects the brain and what biological signs could be targeted in the future.
New Haven, ConnecticutAges 21–60 - NCT05445804RecruitingPhase 1
Oral cannabidiol (CBD) to help you quit tobacco
This Phase 1 study tests whether taking oral CBD can help people quit tobacco. It also checks safety and helps researchers learn how people respond to the treatment while they practice quitting.
Baltimore, MarylandAges 18–65 - NCT07773649RecruitingEarly Phase 1
PET scan to study energy use in brain of people with cocaine use disorder
This study uses a special PET scan to look at how brain cells make energy, which may be changed by cocaine. It might help researchers find better ways to treat cocaine use disorder.
Pittsburgh, PennsylvaniaAges 18–45 - NCT07079215Recruiting
Device trial for opioid withdrawal symptoms
This trial tests a physical device (ADTPM 1) to help manage withdrawal symptoms in people who are dependent on opioids. The goal is to see if the device can safely reduce withdrawal discomfort.
Daegu, DaeguAges 19–80 - NCT05854836Recruiting
Pre-pregnancy support for incarcerated women with substance use
This study tests a preconception (before pregnancy) support program for incarcerated women who have used substances and could become pregnant. It may help improve health and planning before a future pregnancy.
St Louis, MissouriAges 18–49
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Common questions
- Are there clinical trials for alcohol use disorder?
- Yes. Clin2 currently lists 370 recruiting alcohol use disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alcohol use disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alcohol use disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.