Clinical trials
Alcohol Use Disorder clinical trials
Below are recruiting alcohol use disorder clinical trials, each written for real people, not researchers. We’re tracking 370 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07330349Recruiting
Trauma and substance use in penetrating abdominal injury
This study looks at alcohol, drug use, and painkiller use in people with a penetrating abdominal injury (like a stab or gunshot wound to the belly). It aims to understand how these substances affect patient outcomes.
Cali, Valle del Cauca DepartmentAges 15 years+ - NCT04331704RecruitingPhase 4
Alcohol and sexual health program for men at risk of HIV
This study tests an alcohol- and sexual-health program to help reduce HIV risk in men who recently had condomless sex and drink heavily. It may help you by offering structured support around drinking and HIV prevention (PrEP).
Gainesville, FloridaAges 18–30 - NCT06104280Recruiting
How opioid addiction meds affect sleep and eyes
This study tests how three common medications for opioid use disorder (methadone, buprenorphine, and naltrexone) affect eye function, sleep, and daily body rhythms. It may help find ways to improve treatment for opioid addiction.
Birmingham, AlabamaAges 18–80 - NCT06823453Recruiting
Training friends and family to support people who use opioids
This study trains friends and family members of people who use opioids, so they can provide better support and reduce stigma. It also includes people who use opioids to see if this training improves their relationship and well-being.
Chicago, IllinoisAges 18 years+ - NCT05957848RecruitingPhase 2
Guanfacine for teens with cannabis use problems
This Phase 2 study tests whether extended-release guanfacine can reduce cannabis use in adolescents and young adults. It may help by targeting brain pathways that can drive cravings or continued use.
Parkville, VictoriaAges 12–25 - NCT06847165Recruiting
Trigeminal nerve stimulation for kids with prenatal alcohol exposure
This study tests a gentle, non-invasive nerve stimulation device to see if it can improve attention and behavior in children aged 8-12 who were exposed to alcohol before birth and have ADHD. If it helps, it could offer a new way to manage symptoms without medication.
Los Angeles, CaliforniaAges 8–12 - NCT06002633Recruiting
Alcohol effects and brain responses in PTSD
This study explores how people with PTSD respond to alcohol and how their brains handle approach or avoidance situations. You may participate if you drink alcohol occasionally and are between 21 and 60 years old.
Austin, TexasAges 21–60 - NCT05883358Recruiting
Treating kratom withdrawal with clonidine or buprenorphine
This trial studies medicines (clonidine and/or buprenorphine) to help manage kratom dependence and kratom withdrawal symptoms. You may be asked to regularly track withdrawal symptoms in diaries to help the study team monitor safety and response.
Surrey, British ColumbiaAges 20–99 - NCT06470698Recruiting
Using emotional awareness to predict treatment success in addiction
This trial tests whether tracking emotional awareness can help predict how well people recover from cocaine or alcohol addiction. It uses a mobile app to monitor feelings and progress.
HuelvaAges 18 years+ - NCT06457841Recruiting
Stress and Resilience in Afro-Descent Adults
This study looks at how stress and resilience affect people who use alcohol or cannabis to cope. It's for adults of Afro-descent who have used alcohol or cannabis at least a few times recently and are not in treatment for substance use.
Dallas, TexasAges 18–30 - NCT07459244Recruiting
ECG changes in people who use methamphetamine
This study looks at the electrical activity of the heart (ECG) in people who use methamphetamine, including those who develop psychosis from it. It compares them to healthy volunteers to see if methamphetamine affects heart function.
Elâzığ, ElâzığAges 18–65 - NCT06395389Recruiting
A brief program to help young adults cut back on cannabis
This trial tests a short, one-time program designed to help people ages 18-25 who use cannabis frequently (at least 20 days per month) reduce their use. It may be a good fit if you're not already in treatment and are thinking about making a change.
Charleston, South CarolinaAges 18–25 - NCT06218056RecruitingPhase 2
CBD for reducing cigarette smoking in a treatment center
This study tests whether a daily dose of cannabidiol (CBD) can help people who smoke at least 5 cigarettes a day cut down or quit. It is for people staying at a treatment center in Los Angeles where cannabis use is not allowed.
North Hollywood, CaliforniaAges 18–65 - NCT06379984RecruitingPhase 2
Quick-start buprenorphine for opioid addiction with fentanyl use
This trial tests a way to quickly start buprenorphine (a medication for opioid addiction) in an outpatient clinic for people who use fentanyl. It aims to make starting treatment easier and faster, without needing to go through full withdrawal first.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06534047RecruitingPhase 4
Brain stimulation or nicotine patch to help you quit smoking
This study tests whether a brain stimulation treatment called rTMS can help people with psychiatric conditions quit smoking. You will be randomly assigned to get either rTMS or a nicotine patch, and your progress will be tracked to see which treatment works better.
Toronto, OntarioAges 18–70 - NCT06726200RecruitingEarly Phase 1
Comparing buprenorphine formulations for fentanyl addiction
This study tests two different forms of buprenorphine (a medication for opioid addiction) to see which works better for people who use fentanyl or other strong synthetic opioids. If you are seeking treatment for opioid use, this trial may help you find the most effective option.
New York, New YorkAges 18–65 - NCT07042451Recruiting
Testing a phone app to support recovery after substance use treatment
This trial is testing whether a smartphone app called Pink Cloud can help people stay in recovery after finishing substance use treatment. You would need to attend one recovery meeting in the next week and use the app on your personal phone.
Los Angeles, CaliforniaAges 18 years+ - NCT06424184Recruiting
Fast brain stimulation for addiction and depression
This study tests a quick, non-invasive brain stimulation method (rTMS) to help people who use stimulants like cocaine or methamphetamine and also feel depressed. The goal is to see if it can reduce cravings and improve mood.
Dallas, TexasAges 18–65 - NCT05885542RecruitingPhase 1/Phase 2
Testing CBD pills for cannabis use and stress in young adults
This early-phase study tests whether a CBD pill (compared with a placebo sugar pill) can affect cannabis use and stress in people ages 18–25 who use cannabis very frequently. It may help your stress levels and cannabis-related symptoms while researchers carefully monitor safety and abstinence periods during visits.
Charleston, South CarolinaAges 18–25 - NCT07503067Recruiting
Understanding substance use consequences
This study looks at the experiences and consequences of substance use. It is for people who either use substances, care for someone who does, or have a close friend or family member who does.
Belmont, MassachusettsAges 18 years+ - NCT05287711Recruiting
Motivational alcohol support to help prevent partner violence
This study tests an extra (adjunct) counseling approach to reduce harmful alcohol use in Veterans enrolled in the Strength at Home program. The goal is to help prevent intimate partner violence (IPV), especially when alcohol is involved.
Boston, MassachusettsAges 18 years+ - NCT07053098Recruiting
Boosting Alcohol Use Disorder Meds in Psychiatric Care
This study aims to help doctors and staff at three psychiatric clinics better prescribe medications for alcohol use disorder to patients with serious mental illness. It looks at whether extra support and guidance can improve treatment.
Baltimore, MarylandAges 18–90 - NCT05886582RecruitingPhase 2
Rotigotine patch added to therapy for cocaine use
This Phase 2 study tests whether a rotigotine skin patch, used alongside behavioral therapy, can help people reduce cocaine use. It also looks at changes in brain activity while you do study tasks.
Richmond, VirginiaAges 25–70 - NCT06982443Recruiting
Wellness, alcohol, stress, and emotions study
This trial tests whether wearing a sensor to track your heart rate and emotions can help people with moderate to severe alcohol use disorder reduce drinking. You'll attend group meetings and use a phone or computer for 8 weeks.
Albuquerque, New MexicoAges 18 years+
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Common questions
- Are there clinical trials for alcohol use disorder?
- Yes. Clin2 currently lists 370 recruiting alcohol use disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alcohol use disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alcohol use disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.