Clinical trials
Alcohol Use clinical trials
Below are recruiting alcohol use clinical trials, each written for real people, not researchers. We’re tracking 273 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05408247RecruitingPhase 4
N-acetylcysteine to help people cut back on alcohol
This trial tests whether N-acetylcysteine (a supplement-like medicine) can help people with alcohol use disorder reduce or stop drinking. You may be randomly assigned to receive N-acetylcysteine or a comparison treatment, and you’ll complete interviews during the study.
Sydney, New South WalesAges 18–70 - NCT05474989RecruitingPhase 2
LSD-assisted therapy for alcohol use disorder
This Phase 2 trial studies whether an LSD treatment approach, combined with study procedures, can help people with moderate-to-severe alcohol use disorder cut down or stop drinking. It may help reset patterns around cravings and drinking, but it also requires careful safety screening.
BaselAges 25 years+ - NCT05621538Recruiting
Neurofeedback plus brain stimulation for alcohol use disorder
This trial studies whether combining brain “training” (neurofeedback) with noninvasive brain stimulation (TMS) can help people with alcohol use disorder. It may be offered as an additional treatment alongside care you’re already receiving.
Auburn, AlabamaAges 19–65 - NCT05781009RecruitingPhase 2
Pregnenolone treatment for alcohol use disorder
This Phase 2 study tests pregnenolone to help reduce or improve alcohol use disorder symptoms. It looks for adults who drink regularly and meet diagnostic criteria for moderate to severe alcohol use disorder, while excluding people with certain other substance use, medicines, or serious mental/medical conditions.
New Haven, ConnecticutAges 18–70 - NCT05899660Recruiting
Omega-3 for alcohol use disorder during withdrawal
This trial studies whether taking omega-3 supplements during a hospital alcohol-withdrawal program can improve recovery for people with alcohol use disorder. It may help by changing inflammation and how the body responds to stopping alcohol.
BrusselsAges 18–70 - NCT05957159RecruitingEarly Phase 1
Testing an alcohol brain imaging study based on opioid receptor balance
This early-phase study looks at how the brain’s opioid receptor balance may be different in people with alcohol use disorder (AUD), using brain scans and blood testing. It may help researchers understand why some people respond differently to alcohol and related treatments.
New Haven, ConnecticutAges 21–70 - NCT05988632RecruitingPhase 1/Phase 2
Insulin nasal spray for alcohol use disorder
This trial tests whether a nasal spray with insulin can help people with alcohol use disorder. It may affect how the brain responds to alcohol and reduce drinking.
Providence, Rhode IslandAges 21 years+ - NCT05997212Recruiting
Can brain stimulation help with thinking skills in alcohol use disorder?
This study tests if a noninvasive brain stimulation technique called repetitive TMS (rTMS) can improve thinking skills like decision-making and focus in people recovering from alcohol use disorder. You must have been alcohol-free for 8 weeks to 5 years.
Querétaro City, QuerétaroAges 25–59 - NCT06399653Recruiting
Nerve stimulation for alcohol use disorder in veterans
This study tests a non-invasive device that gently stimulates a nerve in your neck (the vagus nerve) to see if it can help reduce alcohol cravings and improve daily functioning. It is designed for veterans who struggle with heavy drinking and want to explore a new treatment option.
San Diego, CaliforniaAges 21–65 - NCT06426303RecruitingPhase 4
Alcohol Use Disorder Treatment in Veterans: Brain and Inflammation
This study is for veterans with alcohol use disorder who have been sober for 5 days to 3 weeks. It looks at how trauma, inflammation, and brain function relate to alcohol problems and how well treatment works. You will be in a group that gets medication or a placebo.
Portland, OregonAges 18–60 - NCT06727331RecruitingPhase 2
Tirzepatide for alcohol use recovery
This trial tests if tirzepatide, a medication that helps with appetite and blood sugar, can help people with alcohol use disorder drink less or stop drinking. You would visit the clinic regularly and receive the drug or a placebo.
Boston, MassachusettsAges 18 years+ - NCT06512389RecruitingPhase 2
Testing CBD for alcohol cravings
This study tests whether a medication called cannabidiol (CBD) can help reduce cravings for alcohol. Over several weeks, you will take the study pill and attend lab sessions where you can choose to drink alcohol in a safe setting.
Toronto, OntarioAges 19 years+ - NCT06518785Recruiting
Ultrasound brain treatment for alcohol use disorder
This study tests if focused ultrasound can help reduce alcohol cravings by stimulating a specific part of the brain. Participants will receive ultrasound treatments and undergo an MRI to see how the brain responds.
San Francisco, CaliforniaAges 18 years+ - NCT06684483Recruiting
Heavy alcohol use and your mouth health
This study looks at how heavy alcohol use affects your saliva and mouth health. It compares people with alcohol use disorder to healthy volunteers to see if the heavy drinking changes the mouth's natural defenses.
Bethesda, MarylandAges 18–100 - NCT06706349Recruiting
Exercise to improve sleep in alcohol use disorder
This study tests whether a personalized exercise program can improve sleep quality in people with alcohol use disorder. You would work with a physical activity coach over several weeks, and your sleep and health would be monitored closely.
BesançonAges 18–65 - NCT06795581RecruitingPhase 1
Brain imaging study for alcohol use disorder
This study uses a special brain scan (PET) to look at a protein called PDE4B in people with alcohol use disorder. The goal is to better understand how alcohol affects the brain, which may lead to new treatments.
Bethesda, MarylandAges 18–70 - NCT06866379Recruiting
Brain study on alcohol use disorder: septal nuclei
This study uses brain scans (fMRI) to look at a small area deep in the brain called the septal nuclei, which may play a role in alcohol use disorder. It aims to understand how the brain's structure and activity relate to heavy drinking, which could lead to better treatments.
FrederiksbergAges 30–65 - NCT06949423Recruiting
Deep TMS for alcohol use disorder
This study tests whether deep transcranial magnetic stimulation (dTMS) can change brain activity related to alcohol use. It is for people who have moderate to severe alcohol use disorder and are willing to attend clinic visits.
Palo Alto, CaliforniaAges 18–75 - NCT06985927Recruiting
Self-Concept and Memory in Alcohol Use Disorder
This study looks at how people with alcohol use disorder remember their past and see themselves. Researchers will ask about your memories and self-image to understand the link between alcohol and thinking patterns.
ReimsAges 24 years+ - NCT06987526Recruiting
Online mindfulness program for alcohol relapse prevention
This trial tests a web-based mindfulness program designed to help people who have recently completed alcohol treatment stay on track and prevent relapse. It uses techniques you can practice online to manage cravings and triggers.
Macon, GeorgiaAges 18 years+ - NCT07029529RecruitingPhase 2
Apremilast for alcohol use disorder
This study tests whether a drug called apremilast can help people who drink heavily reduce their alcohol use. You will take the medication daily for several weeks and attend study visits to track your progress.
New Haven, ConnecticutAges 21–65 - NCT07464613Recruiting
Social thinking in severe alcohol use disorder
This study looks at how people with severe alcohol use disorder process social information, like understanding others' emotions or intentions. It uses brain imaging (MRI) and tests on a smartphone. The goal is to learn more about social cognition in recovery.
Reims, ReimsAges 18–65 - NCT07573540Recruiting
Smart Phone App to Support Alcohol Recovery
This study tests a smartphone app called STAR designed to help people stay in recovery from alcohol use disorder. Researchers want to see if the app helps people maintain their sobriety after they've already stopped drinking.
Madison, WisconsinAges 18 years+ - NCT07612631RecruitingEarly Phase 1
Brain imaging study of alcohol and stress response
This research uses brain imaging to understand how two brain systems—one involved in stress and one involved in reward—interact in people with alcohol use disorder. The goal is to find new ways to help people reduce heavy drinking.
Pittsburgh, PennsylvaniaAges 18–55
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Common questions
- Are there clinical trials for alcohol use?
- Yes. Clin2 currently lists 273 recruiting alcohol use studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alcohol use trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alcohol use trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.