Clinical trials
Alzheimer Dementia (AD) clinical trials
Below are recruiting alzheimer dementia (ad) clinical trials, each written for real people, not researchers. We’re tracking 135 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07115238RecruitingPhase 3
PET imaging study for normal aging, MCI, and Alzheimer's
This trial tests a new PET imaging agent (18F-XTR006) to see how well it shows brain changes related to Alzheimer's disease. It may help diagnose MCI (mild cognitive impairment) or Alzheimer's earlier by comparing images in healthy people and those with memory problems.
Beijing, Beijing MunicipalityAges 50 years+ - NCT07323914RecruitingPhase 3
Pain management for people with Alzheimer's and chronic pain
This study tests if opioid pain medicine is safe and effective for people with Alzheimer's disease who also have chronic pain. It aims to find better ways to manage pain in dementia.
BeijingAges 50–90 - NCT07580703RecruitingPhase 1
Brain Imaging Study for Memory and Thinking Changes
This study tests a new type of brain scan (called [18F]Flortaucipir PET) that may help detect early signs of Alzheimer's disease. Researchers want to make sure the scan is safe and works well in Chinese patients aged 50–85 with normal thinking, mild memory problems, or Alzheimer's disease.
Beijing, Beijing MunicipalityAges 50–85 - NCT06230783Recruiting
Speech test for early Alzheimer's detection
This trial uses speech pattern analysis to detect early signs of Alzheimer's. If you're already in a Wisconsin Alzheimer's study, you may help test if your voice can reveal memory changes.
Madison, WisconsinAges 40–80 - NCT06923007Recruiting
Vagus nerve stimulation for Alzheimer's disease
This trial tests if a nerve stimulation device can help people with mild to moderate Alzheimer's. It is for patients aged 50 to 80 who are on a stable medication.
BeijingAges 50–80 - NCT06953167Recruiting
Dementia study for older adults with prior brain checks
This study follows older adults who have already had amyloid testing, to track changes in memory and thinking over time. It helps researchers understand how to prevent dementia.
LondonAges 65 years+ - NCT04335994Recruiting
Home sleep testing for people with memory trouble
This study looks at how well home sleep apnea testing works for people with cognitive impairment (memory/thinking problems) to help improve outcomes. You may be asked to do a home sleep test (and possibly an in-lab test) and will involve a caregiver if needed.
Toronto, OntarioAges Any age - NCT05617014Enrolling by invitation
ADNI4 study for early Alzheimer’s with brain imaging tests
This study enrolls people with no memory impairment, mild memory problems, or mild Alzheimer’s dementia to test how brain scans and cognitive tests relate to Alzheimer’s disease. It may help by contributing to better early diagnosis and by letting you see whether you fit into the study’s imaging and blood-test pathway.
Birmingham, AlabamaAges 55–90 - NCT06781333RecruitingPhase 2
Stem cells for behavior problems in Alzheimer's
This trial tests whether a single infusion of human mesenchymal stem cells (hMSC) can improve difficult behaviors like agitation, anxiety, or hallucinations in people with Alzheimer's disease. It's designed for those who have been taking antipsychotic medication for at least 4 weeks and have a study partner to help track behavior changes.
Miami, FloridaAges 55–90 - NCT05395624RecruitingPhase 1/Phase 2
Safety imaging study of a PET tracer in ALS, Alzheimer, MS, Parkinson
This early-phase study tests the safety of a radioactive tracer (“18F-OP-801”) and how the tracer moves through the body (biodistribution) in people with ALS, Alzheimer’s disease, multiple sclerosis, Parkinson’s disease, and in healthy volunteers. It also measures how the body processes the tracer (“pharmacokinetics”) to support future studies.
San Francisco, CaliforniaAges 18–80 - NCT07222449Enrolling by invitation
Wearable devices and blood tests for sleep in Alzheimer's
This study uses wrist monitors and blood tests to understand sleep problems in people with Alzheimer's dementia. It aims to improve sleep management through digital therapy and personalized insights.
Beigang, YunlinAges Any age - NCT06855368Recruiting
Biomarkers for tracking dementia progression
This study looks at biological markers to monitor how dementia changes over time. It may help understand the disease better in people with early Alzheimer's or mild cognitive impairment.
RomaAges 18 years+ - NCT07041450Recruiting
Screening for Alzheimer's treatment using digital tests and blood tests
This study is testing whether simple digital memory tests and blood tests can help find people who might qualify for anti-amyloid treatments (medications that target Alzheimer's-related proteins). It aims to make screening easier and faster, without needing a spinal tap or PET scan.
Greenfield Park, QuebecAges 55–90 - NCT07075770Recruiting
New magnetic and electrical brain stimulation for mild Alzheimer's
This trial tests a new, noninvasive treatment that combines magnetic and electrical stimulation to target a specific brain network in people with mild Alzheimer's disease. It aims to slow memory decline and improve brain function.
Rome, ItalyAges 50–85 - NCT07287852Enrolling by invitationPhase 2
Ginkgo biloba extract for mild cognitive impairment
This trial tests whether a specific ginkgo biloba extract (EGb761) can improve thinking and memory in people with mild cognitive impairment (MCI). It also looks at changes in blood markers related to the condition.
JerusalemAges 65 years+ - NCT06817902Enrolling by invitation
TMS for Early Alzheimer's Disease Pilot
This trial tests whether transcranial magnetic stimulation (TMS), a noninvasive brain treatment, can help people with early Alzheimer's or mild cognitive impairment. It aims to see if the treatment is safe and effective for slowing memory decline.
Saint Paul, MinnesotaAges 40–90 - NCT06723015Enrolling by invitationPhase 2
Tau PET in anti-amyloid therapy for Alzheimer's
This study uses brain scans to see how anti-amyloid treatments affect tau protein buildup in people with early Alzheimer's. If you have mild cognitive impairment or mild Alzheimer's, you may be eligible to help understand how these treatments work.
Rochester, MinnesotaAges 50–90 - NCT06362824Recruiting
Physical activity study for older Hispanic adults
This study tests ways to help older Hispanic/Latino(a) adults become more physically active. You will be randomly assigned to one of two programs, and the study lasts up to 20 weeks. It includes wearing a small activity tracker and filling out questionnaires.
San Diego, CaliforniaAges 55–89 - NCT06891716RecruitingEarly Phase 1
PET imaging study for TDP-43 protein disorders
This study uses a special PET scan to detect TDP-43 protein buildup in the brain, which is linked to conditions like frontotemporal dementia and ALS. Healthy volunteers and people with TDP-43 disorders are invited to take part.
AmsterdamAges 40–70 - NCT06995638Recruiting
Multitasking training for older adults
This study tests whether a special online training program can help older adults improve their ability to multitask and stay focused. You'll do some computer exercises at home and come in for a few checkups, including a blood test.
Newark, New JerseyAges 60–75 - NCT06052254RecruitingPhase 2
Skin patch for agitation in Alzheimer's dementia
This trial tests a skin patch that delivers a medicine called dexmedetomidine to help calm agitation in people with Alzheimer's disease. It might be an option for those living in a care facility who have had recent episodes of agitation.
Daytona Beach, FloridaAges Any age - NCT04124029Recruiting
Study how mild brain injuries may relate to dementia
This study looks at how past mild traumatic brain injury may contribute to brain changes seen in chronic traumatic encephalopathy (CTE) and Alzheimer’s disease (AD). It may help researchers understand risk and brain markers by comparing people with mild or moderate TBI, people with mild memory problems, and healthy controls.
Boston, MassachusettsAges 30–90 - NCT04579120Recruiting
Brain scan study in healthy aging or early Alzheimer’s
This study uses brain imaging to understand changes in the brain during normal aging and early Alzheimer’s disease (AD). It may help researchers spot early brain changes and evaluate how well imaging measures those changes.
St Louis, MissouriAges 18 years+ - NCT05800028Recruiting
Study brain scans and social life in memory changes
This study looks at how memory and brain function relate to social interactions. It focuses on people with probable Alzheimer’s disease or a specific language-related condition, and on healthy partners matched by age and social background.
CaenAges 18–85
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Common questions
- Are there clinical trials for alzheimer dementia (ad)?
- Yes. Clin2 currently lists 135 recruiting alzheimer dementia (ad) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alzheimer dementia (ad) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alzheimer dementia (ad) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.