Clinical trials
Alzheimer's Disease Dementia clinical trials
Below are recruiting alzheimer's disease dementia clinical trials, each written for real people, not researchers. We’re tracking 458 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06565143Recruiting
Brain stimulation for early Alzheimer's disease
This trial tests whether a gentle, non-invasive electrical brain stimulation method called tACS can help people in the early stages of Alzheimer's disease. You may be eligible if you have mild cognitive impairment or early dementia and have been on a common Alzheimer's medication for at least 3 months.
Hefei, AnhuiAges 50–85 - NCT05397639RecruitingPhase 3
Masupirdine trial for agitation in Alzheimer’s dementia
This Phase 3 study tests masupirdine to see if it can reduce agitation in people with Alzheimer’s-type dementia. If you have Alzheimer’s dementia with confirmed agitation, joining could help researchers find better treatment options.
Anaheim, CaliforniaAges 50–90 - NCT05372172Recruiting
Tennessee Alzheimer’s study for people 60 and older
This study is looking at how brain and memory changes show up in people across the Alzheimer’s spectrum—from normal thinking to mild memory problems to Alzheimer’s disease. You might join if you can do study visits and an MRI and have a reliable study partner available.
Nashville, TennesseeAges 60 years+ - NCT06417086Recruiting
Acupuncture for Alzheimer's in gene carriers and non-carriers
This trial tests whether acupuncture can help people with Alzheimer's disease. Researchers will compare results in people who carry the APOE e4 gene and those who don't, to see if the treatment works differently.
ShanghaiAges 50–80 - NCT05077579Recruiting
Alzheimer’s scan study for people with higher body weight
This study uses brain scans (MRI and two special PET scans) to see how Alzheimer’s-related changes show up in people who are overweight or obese, with different blood-sugar and insulin patterns. It may help researchers understand whether body weight and metabolism affect early Alzheimer’s markers in the brain.
St Louis, MissouriAges 40–60 - NCT06534723RecruitingPhase 3
Wujia Yizhi granules for mild-to-moderate Alzheimer's
This trial tests if a Chinese herbal granule (Wujia Yizhi) can help people with mild-to-moderate Alzheimer's dementia. It is for patients who have memory problems for at least 6 months and meet specific Alzheimer's biomarker criteria.
Fuzhou, FujianAges 50–80 - NCT07332260RecruitingPhase 1
Fecal transplant for Alzheimer's disease
This study tests whether a fecal transplant (transferring healthy bacteria from a donor's stool into your colon) can improve memory and thinking in people with mild to moderate Alzheimer's. You would receive the transplant via colonoscopy and have follow-up brain scans.
Tromsø, TromsAges 18 years+ - NCT07146412Recruiting
Lifestyle changes to lower dementia risk for older adults
This research study tests whether a program of healthy eating, exercise, and other lifestyle changes can lower your risk for dementia. It is designed for people aged 65–75 with a family history of dementia who want to take steps to keep their brain healthy.
Huntsville, AlabamaAges 65–75 - NCT04961450Enrolling by invitation
Study tracking brain illness markers in motor neuron and frontotemporal disease
This study looks for “biomarkers” (measurable signs in blood or other samples) in people with motor neuron disease and frontotemporal dementia spectrum conditions. It also compares those findings with matched caregivers, to understand what might be happening in these diseases.
Beijing, Beijing MunicipalityAges 18–80 - NCT06889818Recruiting
Alzheimer's treatment and diagnostics registry study
This study creates a registry for people who are using newly approved Alzheimer's medications. It tracks how these treatments work over time and may help researchers learn more about diagnosing and treating Alzheimer's.
IncheonAges 19 years+ - NCT04239079Recruiting
Study of immune-related changes in Parkinson’s and Alzheimer’s
This study looks for “autoimmune-like” (immune-system) features in brain-related diseases such as Parkinson’s and Alzheimer’s, using genetic testing and other assessments. Results may help researchers understand what drives these conditions and who might be more likely to have immune-related changes.
New York, New YorkAges 55–90 - NCT05187819Recruiting
Blood test to help diagnose possible Alzheimer’s
This trial checks whether a simple blood test can help doctors diagnose Alzheimer’s in people who seem to have memory problems. If you’re being evaluated for possible dementia, your doctor may refer you to a memory clinic for testing and follow-up.
StavangerAges 40–100 - NCT07178210Recruiting
Robotic surgery for Alzheimer's disease
This trial tests a new robotic surgery that connects tiny lymph vessels in the head and neck to see if it can help people with Alzheimer's disease. It may improve how the brain clears waste and could slow symptoms.
Palo Alto, CaliforniaAges 50 years+ - NCT05231798RecruitingPhase 2
PET and brain scans in adults with Down syndrome
This study looks at how well a brain chemical system works in adults with Down syndrome as they age, including how it relates to Alzheimer’s-type brain changes and thinking skills. It uses brain scans and memory/thinking tests to see whether these measures can help track risk or changes over time.
Nashville, TennesseeAges 18–55 - NCT07676851Recruiting
Predicting dementia risk in older adults with depression
This study looks at whether certain health factors can predict the risk of dementia in older adults who have depression. Your medical records will be reviewed to help create a risk score.
Nanchang, JiangxiAges 50 years+ - NCT05558709Recruiting
Test for thinking and behavior skills in neurodegenerative disease
This trial checks a new kind of paper-and-pen (or computer-based) test to better measure thinking and social/behavior skills in people with certain brain diseases. It may help researchers improve how these skills are tracked and understood over time.
ParisAges 18–90 - NCT06582199Recruiting
Personalized Alzheimer's study using brain scans and spinal fluid
This study looks at how to better predict and understand Alzheimer's disease by using advanced brain scans and spinal fluid tests. It aims to find ways to identify people who stay healthy longer despite risk factors.
ParisAges 50–90 - NCT06121544Recruiting
Pre-Alzheimer's Study: Find Early Brain Changes
This study is looking for healthy volunteers to help detect the very earliest signs of Alzheimer's disease—before memory loss starts. You will have tests like memory checks, blood draws, brain scans, and a spinal tap to look for Alzheimer's-related changes.
MalmöAges 50–80 - NCT06962111Recruiting
Partner in Care Living Alone Plus study for early-stage dementia
This study tests a workshop to help people with early-stage memory problems who live alone. If you have mild dementia or mild cognitive impairment and can join Zoom sessions, you may be eligible.
Phoenix, ArizonaAges 60 years+ - NCT06059313Recruiting
Personality study for people with memory or behavior changes
This study looks at how personality may have changed before the onset of different types of memory or behavior disorders (like frontotemporal dementia, Alzheimer's, or bipolar disorder). Researchers will talk with a family member or close friend who knew you well before the illness started.
NantesAges 18 years+ - NCT07222449Enrolling by invitation
Wearable devices and blood tests for sleep in Alzheimer's
This study uses wrist monitors and blood tests to understand sleep problems in people with Alzheimer's dementia. It aims to improve sleep management through digital therapy and personalized insights.
Beigang, YunlinAges Any age - NCT05395624RecruitingPhase 1/Phase 2
Safety imaging study of a PET tracer in ALS, Alzheimer, MS, Parkinson
This early-phase study tests the safety of a radioactive tracer (“18F-OP-801”) and how the tracer moves through the body (biodistribution) in people with ALS, Alzheimer’s disease, multiple sclerosis, Parkinson’s disease, and in healthy volunteers. It also measures how the body processes the tracer (“pharmacokinetics”) to support future studies.
San Francisco, CaliforniaAges 18–80 - NCT07218081RecruitingPhase 1
Intermittent deep brain stimulation for early Alzheimer's
This trial tests a treatment that sends gentle electrical pulses to a part of the brain involved in memory and thinking. It is for people with early-stage Alzheimer's who live at home and have a caregiver who can help.
Augusta, GeorgiaAges 65–85 - NCT07731191Recruiting
Digital tools to predict Alzheimer's risk factors
This study uses smartphone tools to track early signs of Alzheimer's by analyzing risk factors. It is for people with mild cognitive issues (MCI) or subjective cognitive decline (SCD) who do not have dementia.
Brescia, BSAges 18 years+
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Common questions
- Are there clinical trials for alzheimer's disease dementia?
- Yes. Clin2 currently lists 458 recruiting alzheimer's disease dementia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alzheimer's disease dementia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alzheimer's disease dementia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.