Clinical trials
Alzheimer's Disease Dementia clinical trials
Below are recruiting alzheimer's disease dementia clinical trials, each written for real people, not researchers. We’re tracking 458 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05919485Recruiting
Brain stimulation study for mild cognitive problems in Parkinson’s
This trial tests whether a type of noninvasive brain stimulation (tDCS) can improve thinking and memory in people with mild cognitive impairment in Parkinson’s disease. You may be eligible if you have these diagnoses, are on stable medications, and can safely complete brain scan/testing.
Antalya, AlanyaAges 45–80 - NCT06793735Recruiting
Virtual reality app for memory and thinking problems
This trial tests a virtual reality app you can use at home to help with early memory or thinking problems. It may be an option if you have mild cognitive impairment or notice your thinking is slowing down.
Messina, ItalyAges 40–80 - NCT06023407Enrolling by invitation
Heat therapy for blood sugar and Alzheimer's prevention
This study tests whether regular heat therapy (like sitting in a hot tub) can help improve blood sugar control and lower the risk of Alzheimer's disease in older women who have metabolic problems.
Kansas City, KansasAges 65 years+ - NCT06596746Recruiting
Tracking markers for neurodegenerative diseases
This study tracks changes in people with Parkinson's disease, other movement disorders, or cognitive decline to find better ways to measure disease progression.
Cassino, FrosinoneAges 10 years+ - NCT07347574Recruiting
Early Alzheimer's detection study in Hong Kong communities
This study aims to find early signs of Alzheimer's in the community through blood tests and assessments. It's for people who can think clearly and agree to participate without major health issues.
Hong KongAges 60–75 - NCT05887674Recruiting
Non-drug memory program for early Alzheimer’s and memory loss
This trial studies a non-medication (non-drug) program to improve memory and daily thinking in people with mild cognitive impairment or mild Alzheimer’s disease. It may help by supporting brain function and monitoring symptoms over time.
Shanghai, Shanghai MunicipalityAges 60–90 - NCT06722352Recruiting
Palliative care education for dementia in assisted living
This study trains staff in assisted living facilities to better support residents with dementia and their families in planning future care. It focuses on helping families talk about advance care planning (decisions about future medical care) with the care team.
Tampa, FloridaAges 21 years+ - NCT05306834Recruiting
Study to slow memory decline by targeting hidden small brain vessel disease
This trial looks at how to slow cognitive decline and early dementia in people with a specific kind of “silent” blood vessel damage in the brain seen on scans. It may help identify whether targeting this hidden condition can protect thinking and memory over time.
BordeauxAges 60–88 - NCT05977088Recruiting
Testing rTMS to help memory in Alzheimer’s
This study tests whether a brain stimulation treatment called rTMS can improve symptoms in people with Alzheimer’s disease. It mainly looks at people with mild to moderate dementia and checks whether results differ based on how the treatment is applied.
IstanbulAges 55 years+ - NCT07688460RecruitingPhase 4
Blood test to monitor Alzheimer's drug Lecanemab
This study tests a drug called Lecanemab in people with early Alzheimer's. It uses a blood test to see how well the drug works. You may qualify if you have mild Alzheimer's or mild cognitive impairment due to Alzheimer's and have a positive amyloid test.
Yiwu, ZhejiangAges 50–90 - NCT07236190RecruitingPhase 2
Using brain markers to test NPC-1 for Alzheimer's
This trial tests whether NPC-1, a new drug, can help people with early memory changes or Alzheimer's. Your blood or PET scan will show if you have Alzheimer's-related brain changes, which is required for this study.
Boston, MassachusettsAges 55 years+ - NCT07420075Enrolling by invitation
Alzheimer's registry for people with memory problems
This registry collects information from people with mild cognitive impairment or Alzheimer's disease who are starting a new medication. It helps researchers learn more about these conditions and their treatments over time.
Waltham, MassachusettsAges 18 years+ - NCT06292741Recruiting
Autonomic system test in people with memory loss
This study tests how the body's automatic functions (like heart rate and blood pressure) change in people with mild memory loss. It may help find early signs of nervous system problems.
Rome, LazioAges 50–85 - NCT04500847RecruitingPhase 1
Testing repurposed HIV-like drugs for early Alzheimer’s symptoms
This Phase 1 study tests whether an existing type of anti-viral medicine (nucleoside reverse transcriptase inhibitors) can help people with early Alzheimer’s disease. It also focuses on safety and proper dosing while measuring brain-related changes and memory-related symptoms.
Los Angeles, CaliforniaAges 50–85 - NCT07679906Recruiting
Nationwide digital study for Alzheimer’s prevention and trial readiness
This study uses a saliva sample and online tools to see if you have a genetic risk factor for Alzheimer’s. It aims to build a large group of people who may be at higher risk, so they can be invited to future prevention trials.
HuningueAges 45 years+ - NCT02414178Enrolling by invitation
Tau PET brain scan for inherited Alzheimer’s disease
This study uses a special brain scan to measure “tau” buildup in people with an inherited form of Alzheimer’s. It may help researchers better understand disease changes and evaluate whether the scan can track them over time.
St Louis, MissouriAges 18 years+ - NCT05886114Recruiting
Lifestyle program to help older adults at risk of memory decline
This trial tests a multi-part lifestyle program to help older adults who may be starting to decline in thinking and memory. It may help slow cognitive decline by combining lifestyle changes over 24 months.
Hangzhou, ZhejiangAges 60–80 - NCT07509125Recruiting
Ultra-high resolution PET brain scans for aging, dementia, and psychosis
This study uses a new ultra-high resolution PET scanner to look at brain changes in healthy aging, dementia, ALS, movement disorders, and psychosis. It aims to better understand these conditions and improve imaging techniques.
Leuven, Vlaams-BrabantAges 18–90 - NCT06230783Recruiting
Speech test for early Alzheimer's detection
This trial uses speech pattern analysis to detect early signs of Alzheimer's. If you're already in a Wisconsin Alzheimer's study, you may help test if your voice can reveal memory changes.
Madison, WisconsinAges 40–80 - NCT07558785Enrolling by invitation
Testing speech and memory checks at home for early thinking problems
This study uses a video-based system at home to check your speech and memory, helping doctors spot thinking problems early using artificial intelligence. The goal is to see if this simple, at-home test can reliably catch early memory and thinking changes.
PilsenAges 40 years+ - NCT07402356Recruiting
Virtual reality eye test for thinking problems
This study uses virtual reality and eye-tracking (pupillometry) to measure thinking and memory problems in people with Alzheimer's, mild cognitive impairment, or depression. It aims to find better ways to detect and track cognitive changes using a simple, non-invasive procedure.
München, BavariaAges 18–80 - NCT06953167Recruiting
Dementia study for older adults with prior brain checks
This study follows older adults who have already had amyloid testing, to track changes in memory and thinking over time. It helps researchers understand how to prevent dementia.
LondonAges 65 years+ - NCT06784830Recruiting
Nursing care for Alzheimer's patients during PET/CT scans
This trial tests a special nursing care plan for Alzheimer's patients during PET/CT brain scans. The goal is to make the imaging experience more comfortable and safe for people with memory loss.
Chengdu, SichuanAges Any age - NCT05456503RecruitingPhase 3
PET scan study of tau buildup in memory and brain disorders
This Phase 3 study uses a PET/CT scan to measure whether a brain protein called tau (and related disease patterns) builds up in different dementia conditions. The goal is to better match which disorders have which brain changes and how they progress.
Philadelphia, PennsylvaniaAges 18 years+
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Common questions
- Are there clinical trials for alzheimer's disease dementia?
- Yes. Clin2 currently lists 458 recruiting alzheimer's disease dementia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alzheimer's disease dementia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alzheimer's disease dementia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.