Clinical trials
Alzheimer's Disease Dementia clinical trials
Below are recruiting alzheimer's disease dementia clinical trials, each written for real people, not researchers. We’re tracking 459 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07486037Recruiting
Exercise program for African American Alzheimer's caregivers
This study is for African American caregivers of someone with Alzheimer's or a related dementia. It explores whether a gentle exercise program can help you feel better and manage the stress of caregiving.
Indianapolis, IndianaAges 18–99 - NCT07208734Enrolling by invitation
Personalized brain stimulation for memory loss in older adults
This trial tests a personalized brain stimulation treatment for older adults with mild memory or thinking problems caused by Alzheimer's disease. It aims to see if tailored stimulation can improve cognitive function.
Beijing, Beijing MunicipalityAges 50–90 - NCT07191821Enrolling by invitationPhase 2
TSPO modulation for Alzheimer's disease
This trial tests a drug that targets a brain protein called TSPO in people with mild to moderate Alzheimer's. It aims to see if this approach can slow memory loss.
LondonAges 18–90 - NCT04124029Recruiting
Study how mild brain injuries may relate to dementia
This study looks at how past mild traumatic brain injury may contribute to brain changes seen in chronic traumatic encephalopathy (CTE) and Alzheimer’s disease (AD). It may help researchers understand risk and brain markers by comparing people with mild or moderate TBI, people with mild memory problems, and healthy controls.
Boston, MassachusettsAges 30–90 - NCT05282550RecruitingPhase 2
Trazodone trial to improve sleep in early Alzheimer’s
This study tests whether the sleep medicine trazodone can improve thinking and memory in people with early Alzheimer’s-related changes who also have sleep problems. If better sleep helps the brain, it may improve memory test results over time.
Baltimore, MarylandAges 55 years+ - NCT05452031Recruiting
Sleep program for people with dementia and their caregiver
This study tests a “dyadic” sleep health approach, meaning it works with both you and your caregiver together. It aims to improve sleep when dementia is causing frequent sleep problems, and to see whether a caregiver-involved plan helps both of you.
La Jolla, CaliforniaAges 18 years+ - NCT05591027RecruitingPhase 1
Testing Centella asiatica for memory problems in older adults
This Phase 1 study tests whether Centella asiatica (a plant-based supplement) is safe and reaches its intended target in people with mild cognitive impairment or early Alzheimer’s disease. It also checks how it affects memory-related brain measures like MRI scans, which is why multiple scans are required.
Portland, OregonAges 60–85 - NCT05822362RecruitingPhase 2
CBD for People with Early Memory Trouble Risk
This Phase 2 study tests whether CBD (a cannabis-derived product) can improve thinking and memory in people who are at risk for Alzheimer’s disease. You would be followed for about 24 weeks with memory/thinking check-ins and require a study partner to help with certain assessments.
Aurora, ColoradoAges 55–85 - NCT05943834Recruiting
Voice testing to detect early memory and mood changes
This trial studies whether automated analysis of your voice and speech can help detect early signs of Alzheimer’s disease and mood (affective) problems. It may help identify changes sooner, using voice and questionnaire information from people who are cognitively healthy to very mildly affected.
NiceAges 50–100 - NCT06429124Recruiting
Time-restricted eating for mild cognitive impairment
This trial tests whether a time-restricted eating schedule (eating only during certain hours of the day) can help people with mild cognitive impairment (MCI) or early Alzheimer’s disease. It is a lifestyle study that can be done mostly from home with a computer or smartphone.
Phoenix, ArizonaAges 55–89 - NCT06618807Recruiting
Infrared light for memory loss in mild cognitive impairment
This study tests whether shining a gentle infrared light on the head can help people with mild memory loss (MCI) improve their thinking and memory. It is designed for those who have mild cognitive impairment due to early Alzheimer's disease.
Toronto, OntarioAges 50 years+ - NCT07383311Recruiting
Memory, sleep, and a natural supplement
This trial tests whether a natural substance (from wheat germ) that boosts a process called autophagy can help improve sleep in people who are worried about their memory or have mild memory problems but do not have dementia.
Greifswald, Mecklenburg-VorpommernAges 55–70 - NCT07328386Recruiting
Neck surgery for brain lymphatic disorder
This trial tests a neck surgery (lymphaticovenous and lymph node-to-vein anastomosis) to see if it improves symptoms in people with Alzheimer's disease linked to a brain lymphatic circulation disorder. It focuses on those with moderate-stage Alzheimer's and confirmed amyloid buildup.
SeoulAges 19–100 - NCT02685969Recruiting
Brain scan study of amyloid and brain sugar use
This study uses brain imaging to measure two things in the brain—amyloid protein and how the brain uses sugar. It may help researchers better understand early brain changes in people in the ALFA project.
Barcelona, CataloniaAges 45–75 - NCT07672938Recruiting
Olive supplement and Mediterranean diet for mild memory loss
This trial tests whether a dietary supplement made from olive polyphenols, combined with following a Mediterranean diet, can help protect thinking and memory in people with mild cognitive impairment (MCI). It may be a good fit if you have early memory changes and want to try a nutrition-based approach.
Thessaloniki, Central MacedoniaAges 50–85 - NCT07457138Recruiting
Brain health study for people with memory worries
This study looks at people who are worried about their memory or thinking skills, even if tests show no problems. It aims to understand brain health over time in a Lombardy clinic.
Costa Masnaga, LombardyAges 18 years+ - NCT07466394Recruiting
Early detection of thinking problems study
This study tests a new way to find early signs of memory or thinking problems in older adults. It could help identify people who might benefit from earlier support or treatment.
MünchenAges 60 years+ - NCT07580703RecruitingPhase 1
Brain Imaging Study for Memory and Thinking Changes
This study tests a new type of brain scan (called [18F]Flortaucipir PET) that may help detect early signs of Alzheimer's disease. Researchers want to make sure the scan is safe and works well in Chinese patients aged 50–85 with normal thinking, mild memory problems, or Alzheimer's disease.
Beijing, Beijing MunicipalityAges 50–85 - NCT07611396Recruiting
Study of brain changes in memory and thinking with aging
This study follows people with normal thinking, early memory problems, or Alzheimer's disease to understand how the brain changes over time. Researchers will use smell tests, blood work, and memory testing to learn more about these conditions and potentially help future treatments.
Germantown, MarylandAges 55 years+ - NCT07643363Recruiting
Brain Stimulation for Cognitive Impairment in Dementia
This study tests a new brain stimulation technique called temporal interference stimulation to help slow cognitive decline in people with Alzheimer's disease or frontotemporal dementia. Researchers will combine this stimulation with cognitive training to see if it improves memory and thinking skills.
Tianjin, Tianjin MunicipalityAges 45–85 - NCT07298876Enrolling by invitation
Ultrasound for memory and sleep in early Alzheimer's
This study tests if a gentle ultrasound treatment to the brain can help improve memory and sleep quality in people with very early Alzheimer's disease. If you have mild memory issues and trouble sleeping, this low-intensity approach might be a safe option to explore.
Hong Kong, Tai Po DistrictAges 60–85 - NCT06843109Enrolling by invitation
Memory clinic study on biomarkers for mild cognitive impairment
This study looks at brain changes in people with mild memory problems to find early signs of Alzheimer's disease. You and a study partner can help by sharing information about your daily life.
London, OntarioAges 55–80 - NCT06379594Enrolling by invitation
Remote brain health clinic for mild memory problems
This study tests a remote 'brain health clinic' for people with mild memory or thinking problems (mild cognitive impairment). It aims to help diagnose the cause of memory issues from home, so you don't need to travel to a clinic.
London, Denmark HillAges 18 years+ - NCT06052254RecruitingPhase 2
Skin patch for agitation in Alzheimer's dementia
This trial tests a skin patch that delivers a medicine called dexmedetomidine to help calm agitation in people with Alzheimer's disease. It might be an option for those living in a care facility who have had recent episodes of agitation.
Daytona Beach, FloridaAges Any age
Hear when a new Alzheimer's Disease Dementia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for alzheimer's disease dementia?
- Yes. Clin2 currently lists 459 recruiting alzheimer's disease dementia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alzheimer's disease dementia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alzheimer's disease dementia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.