Clinical trials · Washington, D.C., DC
Amyotrophic Lateral Sclerosis clinical trials in Washington, D.C.
We’re tracking 16 recruiting amyotrophic lateral sclerosis studies with a site in or near Washington, D.C. — including Early Phase 1, Phase 1 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Washington, D.C.
- NCT06581861Recruiting
Family study to prevent ALS and FTD
This study is for adults who have a strong family history of ALS or FTD (like a parent or sibling with the disease) to help researchers understand how to prevent these conditions. It involves following you for about a year to track your health.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06665165RecruitingPhase 1
Study of AMX0114 for people with ALS
This study tests an experimental drug called AMX0114 for people recently diagnosed with ALS. It is an early-phase trial to see if the drug is safe and how it affects the body.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06578195Recruiting
Assess all ALS study
This study follows people with ALS and healthy volunteers over time to understand the disease better. You can join from home using a smartphone or computer.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05137665Recruiting
Study tracks ALS and health markers over time at home
This study follows people with ALS and healthy volunteers to measure how specific body fluids, symptoms, and at-home tracking change over time. It may help researchers find early signs of disease changes and better ways to measure treatment effects.
Georgetown, District of ColumbiaAges 18 years+ - NCT07204977RecruitingPhase 1
Acamprosate for ALS with C9orf72 gene change
This trial tests a medication called acamprosate to see if it can slow down ALS in people who have a specific genetic change (C9orf72). If you have this gene change and ALS, this study might offer a new treatment option.
Bethesda, MarylandAges 18–99 - NCT04363684Recruiting
Study of frontotemporal dementia and related syndromes over time
This study follows people with frontotemporal dementia (FTLD) and related conditions, and collects health and (for some people) body fluid information, to understand how these illnesses change over time. It may help researchers track disease signs and find better ways to measure progression.
Bethesda, MarylandAges 18 years+ - NCT04394871Recruiting
Study of ALS and related genetic nerve disorders using scans and fluid tests
This study looks at signs and biology (biomarkers) in people with certain inherited nerve conditions caused by RNA-processing gene changes. It may help researchers understand disease patterns and measure health changes using MRI scans and sometimes a spinal fluid test.
Bethesda, MarylandAges 5–120 - NCT03225144Recruiting
Study of gene and disease changes in ALS and frontotemporal dementia
This study looks at complex brain and body changes in people with ALS and frontotemporal dementia (FTD), or related disorders. If you have one of these diagnoses—or a known gene mutation that can cause ALS/FTD—you may be able to help researchers learn how the conditions progress.
Bethesda, MarylandAges 18–110 - NCT03127267RecruitingPhase 3
Test of masitinib versus placebo for ALS
This Phase 3 study tests whether masitinib works better than an inactive pill (placebo) to slow ALS progression and keep it safe. It is meant for people recently diagnosed with ALS who meet specific breathing and function score requirements.
Baltimore, MarylandAges 18–81 - NCT07290062RecruitingPhase 1
Gene therapy injection for ALS safety study
This trial tests a single injection of a gene therapy called INS1202 into the spinal fluid. It is for people with ALS, including those with a specific genetic form (SOD1 mutation). The goal is to see if it is safe and how it affects the body.
Baltimore, MarylandAges 18–79 - NCT07322003RecruitingPhase 3
Pridopidine for ALS: Phase 3 trial testing safety and effectiveness
This trial is testing if an oral medication called pridopidine can slow the progression of ALS. It is for people recently diagnosed with ALS who have mild to moderate breathing function and meet specific risk scores.
Baltimore, MarylandAges 18–80 - NCT07221240RecruitingPhase 1
Amisodin safety study for healthy adults with ALS
This trial tests a new drug called Amisodin in healthy adults who also have ALS. It checks if the drug is safe and how the body processes it.
Baltimore, MarylandAges 18–55 - NCT07823101Recruiting
Imaging study of swallowing and speech muscles in muscle diseases
This study uses imaging to look at the muscles involved in swallowing and speaking in people with certain muscle diseases, like inclusion body myositis or ALS. The goal is to better understand these conditions, which might help improve care in the future.
Baltimore, MarylandAges 18 years+ - NCT06656702RecruitingEarly Phase 1
Psilocybin for depression in amyotrophic lateral sclerosis
This trial tests whether psilocybin, a psychedelic drug, can safely help with depression in people with ALS. It also looks at how the drug affects your symptoms and quality of life over six months.
Baltimore, MarylandAges 18 years+ - NCT03567213Recruiting
CortiCom brain signal system for communication in severe paralysis
This trial tests a system that records brain signals to help people with severe paralysis and little or no speech communicate. It involves a surgical implant and frequent study visits to see if the system can work safely and reliably for communication.
Baltimore, MarylandAges 22–70 - NCT07521930Recruiting
Brain implant to restore communication and movement control
This trial tests a surgically implanted brain device designed to help people with severe paralysis or movement disorders regain the ability to communicate and control their limbs. The device reads signals from your brain and translates them into commands that could help you interact with computers or assistive technology.
Baltimore, MarylandAges 18–80
Hear when a new Amyotrophic Lateral Sclerosis trial opens near Washington, D.C., DC
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Amyotrophic Lateral Sclerosis trials in other cities
Where these studies are running near Washington, D.C.
Institutions with a site for the recruiting amyotrophic lateral sclerosis studies listed above.
- Johns Hopkins University · 4 studies
- Georgetown University · 3 studies
- National Institutes of Health Clinical Center · 3 studies
- Johns Hopkins Medicine · 2 studies
- Georgetown University Hospital Pasquerilla Healthcare Center
- Johns Hopkins Center for Psychedelic and Consciousness Research
- Johns Hopkins Hospital
- Johns Hopkins Medicine Brain Science Institute
What taking part in a amyotrophic lateral sclerosis study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting amyotrophic lateral sclerosis studies in District of Columbia.
Common questions
- Are there amyotrophic lateral sclerosis clinical trials near Washington, D.C.?
- Yes. We're currently tracking 16 recruiting amyotrophic lateral sclerosis studies with a site near Washington, D.C., each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a amyotrophic lateral sclerosis study near Washington, D.C.?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Washington, D.C. to take part?
- Not necessarily. These studies have a site near Washington, D.C., but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a amyotrophic lateral sclerosis trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New amyotrophic lateral sclerosis studies open near Washington, D.C. regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.