Clinical trials
Anhedonia clinical trials
Below are recruiting anhedonia clinical trials, each written for real people, not researchers. We’re tracking 34 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06776991Recruiting
Social anxiety and public speaking fear study
This study tests if reward processing training combined with exposure therapy helps people with social anxiety disorder who are afraid of public speaking. Participants will complete therapy sessions and possibly an MRI brain scan.
Los Angeles, CaliforniaAges 18–60 - NCT06829953Recruiting
App-based study for teens with depression
This study is testing whether a smartphone app can help teens who feel depressed and have lost interest in things. It's looking for youth aged 12–18 with moderate to severe depression who are willing to use the app.
Philadelphia, PennsylvaniaAges 12–18 - NCT06982820Recruiting
Brain training therapy for depression with loss of interest
This trial tests a new type of brain training (self-neuromodulation) to help people with major depression who also have a significant loss of interest or pleasure (anhedonia). If you qualify, you may get a non-invasive treatment that uses real-time brain feedback to improve symptoms.
Providence, Rhode IslandAges 22–75 - NCT07078227Recruiting
Long-term depression follow-up study
This study follows up with people who took part in an earlier research project on depression and genetics. The goal is to see how depression changes over time.
LundAges 18 years+ - NCT07146503Recruiting
Esketamine Nasal Spray for Treatment-Resistant Depression in Real Life
This study tests esketamine nasal spray (a fast-acting antidepressant) for people with treatment-resistant depression who haven't gotten better after trying at least two other antidepressants. It looks at how well the spray works in everyday doctor's offices, not just in research clinics.
Genova, GeAges 18–74 - NCT07319143Recruiting
Can brain stimulation boost emotional health?
This trial uses a gentle brain stimulation technique called tDCS to see if it can improve emotional well-being. It is for healthy young adults who speak Cantonese or Mandarin.
Hong KongAges 18–35 - NCT07386730RecruitingPhase 1
Psychedelic therapy study for older adults with low well-being
This study tests if a single dose of psilocybin (a psychedelic) or dextromethorphan (a cough suppressant) can improve well-being in healthy older adults who feel their well-being is below average. It aims to understand how these drugs might help boost mood and life satisfaction.
San Francisco, CaliforniaAges 50–85 - NCT07490353RecruitingPhase 1
Can psilocybin help treat loss of pleasure?
This trial tests if psilocybin, a psychedelic substance, can improve the ability to feel pleasure (anhedonia) in people with depression who are not taking antidepressants. It also includes healthy volunteers as a comparison group.
Vienna, State of ViennaAges 18–55 - NCT07661901Recruiting
Reward sensitivity app for teens with suicidal thoughts
This trial tests a smartphone-based program designed to help teens who have had recent thoughts of suicide. It aims to see if the app can reduce suicide risk by boosting sensitivity to rewards in daily life.
Philadelphia, PennsylvaniaAges 13–17 - NCT06026904Enrolling by invitation
Testing vagus nerve stimulation for motivation in depression
This trial tests if a gentle nerve stimulation device can improve motivation and interest in people with depression and a lack of pleasure or drive. You keep taking your usual antidepressant pill during the study.
Hefei, AnhuiAges 18–60
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Common questions
- Are there clinical trials for anhedonia?
- Yes. Clin2 currently lists 34 recruiting anhedonia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a anhedonia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a anhedonia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.