Clinical trials
ARDS (Moderate or Severe) clinical trials
Below are recruiting ards (moderate or severe) clinical trials, each written for real people, not researchers. We’re tracking 1,504 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04678154RecruitingPhase 3
Antibiotic trial for severe open fractures of the leg or foot
This trial tests a new way of giving antibiotics to people with severe open fractures in the leg, ankle, or foot. The goal is to see if it helps prevent infections after surgery.
Redwood City, CaliforniaAges 18–64 - NCT05738720Recruiting
Home breathing rehab to reduce COPD flare-ups and hospital visits
This trial tests whether a breathing and exercise program done at home can lower COPD flare-ups and the chance of needing hospital care. It may help people with more severe COPD manage breathlessness and stay stable.
IstanbulAges 18–75 - NCT04227314RecruitingPhase 3
Apremilast vs placebo for severe recurrent mouth ulcers
This Phase 3 trial tests whether apremilast can reduce severe, recurring mouth ulcers compared with an inactive placebo. It aims to improve ulcer frequency and pain while carefully checking safety.
AmiensAges 18 years+ - NCT03711175Enrolling by invitation
Repairing a shoulder tendon after reverse shoulder replacement
This study looks at whether repairing a specific shoulder tendon (the subscapularis) improves outcomes after reverse shoulder replacement. You may be eligible if you’re getting a reverse shoulder implant because of severe arthritis and your tendon is strong enough to repair on MRI.
St Louis, MissouriAges 21 years+ - NCT03646058RecruitingPhase 3
Add-on buprenorphine to ease suicidal thoughts in depression
This Phase 3 study tests whether adding buprenorphine to your usual pain-dose medicines can reduce severe suicidal thoughts during a major depressive episode. It may help people who are currently hospitalized or closely followed and have higher scores for both depression severity and suicidal thinking.
Bordeaux, FranceAges 18–65 - NCT04484675RecruitingPhase 4
Milrinone during heart surgery for severe pulmonary hypertension
This trial tests whether giving milrinone through a vein and inhaled during mitral valve surgery helps people with severe pulmonary hypertension. The goal is to improve heart and lung blood-flow stability around the time of surgery.
Zagazig, Sharqia ProvinceAges 18 years+ - NCT04432220RecruitingPhase 4
Taking blood thinners one year after atrial fibrillation ablation
This study looks at whether people who have stayed in normal rhythm one year after atrial fibrillation ablation should continue blood thinning treatment. It may help guide safer, more personalized choices about long-term blood thinners after a successful procedure.
SeoulAges 19–80 - NCT04395937Recruiting
Study of gentle aerobic exercise to improve severe asthma control
This trial studies whether a lower-intensity aerobic exercise program (not maximal effort) can improve asthma symptoms and control. It is meant for adults with asthma who are still not well controlled despite current inhaler treatments.
Liège, LiegeAges 18–65 - NCT02531893Recruiting
Therapy for youth with severe, frequent irritability
This study tests whether two structured therapies can reduce severe irritability and angry reactions in children and teens. It focuses on youth who have had long-lasting, frequent outbursts and trouble responding to negative emotions.
Bethesda, MarylandAges 8–17 - NCT05689034RecruitingPhase 2/Phase 3
Azvudine for early COVID-19 in higher-risk adults
This trial studies azvudine in adults with early COVID-19 symptoms to see if it can prevent the illness from getting severe. You may qualify if you’re within about 5 days of symptom start and have risk factors for worsening disease.
Beijing, Beijing MunicipalityAges 18–120 - NCT05888987Recruiting
New test for severe corneal infection diagnosis
This study tests a new method for identifying bacteria causing severe corneal infections. It may help doctors choose the right treatment faster by improving how the infection is identified from corneal samples.
ReimsAges 18 years+ - NCT06756672Recruiting
Helping with recovery in laparoscopic colorectal surgery
This study looks at how a system called HPI (a way to track your body's response during surgery) might help people recover better after laparoscopic colorectal surgery. It is for people having this planned surgery who do not have serious heart or lung problems.
TaipeiAges 20 years+ - NCT00903110Recruiting
Long-term safety registry for Increlex in children
This study is a registry that follows children and teens with severe IGF-1 deficiency who use Increlex (or specific GH gene deletion situations) to better track long-term safety and effectiveness. You would likely join if your child is already starting or planning Increlex and is not in other growth-related drug trials.
Orange, CaliforniaAges 2–18 - NCT03389542Recruiting
Early mitral valve repair versus watchful waiting
This trial compares doing mitral valve repair early versus closely monitoring without surgery in people who have severe leakage but no symptoms. It aims to see whether early repair helps prevent future heart problems.
AmiensAges 18–75 - NCT07433504Recruiting
Tricuspid valve clipping for leaky valve
This trial tests a new device that clips the tricuspid valve to stop blood from flowing backward. It is for people with severe tricuspid regurgitation (a leaky valve) who still have symptoms despite medical treatment.
ShanghaiAges 18 years+ - NCT07666438Recruiting
Lung infections in children with chronic lung disease of prematurity
This study looks at children born very early who have chronic lung disease (BPD) and get a lung infection. Doctors want to learn more about how these infections affect breathing and health over time.
Bologna, BolognaAges 4 weeks–7 years - NCT06740799RecruitingPhase 1
Quizartinib study for people with severe liver problems
This trial tests how the body processes quizartinib when the liver is severely impaired. It helps doctors understand if the dose needs to be adjusted for patients with liver issues.
Miami, FloridaAges 18–75 - NCT06409689Recruiting
Oliceridine for pain relief after upper abdominal surgery
This study tests a new pain medicine called oliceridine after laparoscopic upper abdominal surgery. It aims to improve pain control and recovery compared to standard opioids.
Wuhan, HubeiAges 18–70 - NCT06335381Recruiting
Moms Chat and Care study for Black and Latina pregnant patients
This study tests a support program for Black and Latina pregnant people to help reduce pregnancy complications like preeclampsia. It uses text messaging and coaching to improve care and outcomes.
Manhasset, New YorkAges 18–50 - NCT06182969RecruitingPhase 1/Phase 2
APG-2575 for mild to moderate lupus
This trial tests an experimental drug called APG-2575 for people with mild to moderate lupus. It aims to see if the drug can help control lupus activity and improve symptoms.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06261424Recruiting
Exercise program for spastic ataxia types ARSACS and SPG7
This study tests whether a supervised exercise program (including pool exercises) can help people with certain types of hereditary ataxia. The goal is to see if it reduces symptoms like muscle stiffness and coordination problems.
Baie-Saint-Paul, QuebecAges 16 years+ - NCT07499466Recruiting
Peer support for breastfeeding mothers facing hardship
This study tests whether extra support from another mother (a peer supporter) can help women who are facing serious financial or social challenges successfully breastfeed. If you are a new mother with a baby at HFME, want to breastfeed, and are struggling economically, this program may offer free, friendly help.
Bron, FranceAges 18 years+ - NCT04271488RecruitingPhase 1
Study drug levels in people with mild or moderate liver problems
This Phase 1 study measures how tasurgratinib (E7090) and its breakdown product move through the body in people with mild or moderate liver impairment. It aims to understand appropriate dosing and safety considerations for liver impairment.
Hakata, FukuokaAges 20–79 - NCT06257329Recruiting
Studying severe COPD flare-ups in the ICU
This trial is looking at patients with a serious worsening of their chronic obstructive pulmonary disease (COPD) who need intensive care. It aims to gather information to help improve treatment for these severe episodes.
Le ChesnayAges 40 years+
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Common questions
- Are there clinical trials for ards (moderate or severe)?
- Yes. Clin2 currently lists 1,504 recruiting ards (moderate or severe) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ards (moderate or severe) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ards (moderate or severe) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.