Clinical trials
ARDS (Moderate or Severe) clinical trials
Below are recruiting ards (moderate or severe) clinical trials, each written for real people, not researchers. We’re tracking 1,504 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07490925Recruiting
Breathing Machine Strategy to Protect the Heart in ARDS
This trial tests a special breathing machine strategy that uses pressure measurements from a small tube in your esophagus (food pipe) to protect your heart's right side while treating ARDS caused by pneumonia. It may help if you have severe lung failure and need a ventilator.
BeijingAges 18 years+ - NCT07362537Recruiting
Feeding while on stomach for severe lung failure
This study tests if giving nutrition through a feeding tube is safe and effective for patients with severe lung failure who need to lie on their stomach to help breathing. It may help doctors understand how to best feed patients during this treatment.
Nanjing, JiangsuAges 18–85 - NCT07726940Recruiting
A Study of Immune Responses and ECMO in Severe Lung Injury
This study looks at how the immune system and ECMO (a machine that helps oxygenate blood) can improve outcomes for people with moderate to severe ARDS. If you join, researchers will monitor your condition and treatment to find better ways to manage this serious lung problem.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06967285Recruiting
Prone positioning for ARDS: checking brain blood flow
This trial studies how lying on your stomach (prone positioning) affects blood flow in the brain during severe lung failure (ARDS). It aims to predict and prevent brain problems that might occur with this treatment.
Chengdu, SichuanAges 18 years+ - NCT07558538RecruitingEarly Phase 1
Inhaled Growth Factor Treatment for Severe Lung Failure
This early-stage trial tests whether an inhaled medication called recombinant human keratinocyte growth factor-2 (rh-KGF-2) can help patients with acute respiratory distress syndrome (ARDS)—a serious condition where the lungs cannot deliver enough oxygen to the blood. The drug is designed to help repair lung tissue damage.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06691464Enrolling by invitation
Using FAPI PET/CT to find lung scarring in non-healing ARDS
This study uses a special PET/CT scan to look for active scar tissue (fibrosis) in the lungs of people who are still very sick with ARDS after 5 days of ventilator support. It may help doctors understand why some lungs don't heal and could guide future treatments.
Groningen, Provincie GroningenAges 20 years+ - NCT06849570Recruiting
Tailoring breathing support and muscle relaxants during prone positioning for severe lung injury
This trial tests two ways to adjust ventilator settings for patients with severe lung injury whose oxygen levels are very low. It aims to find out the best level of breathing support and whether giving muscle relaxants during prone positioning helps improve oxygen levels.
Aix-en-ProvenceAges 18 years+ - NCT06832306Recruiting
Diaphragm pacing for breathing support in ICU
This trial tests a device that helps stimulate the diaphragm to improve breathing in patients who need a ventilator. It's for people with new breathing problems who have been in the ICU on a ventilator for less than 4 days.
La Jolla, CaliforniaAges 18 years+ - NCT06212492Recruiting
Muscle relaxants and stomach positioning for ARDS
This trial tests whether combining two treatments—medications that relax muscles (neuromuscular blocking agents) and lying on your stomach (prone positioning)—can reduce lung damage in people with severe ARDS on a breathing machine.
MarseilleAges 18 years+ - NCT06514209Recruiting
Muscle relaxation levels in severe ARDS patients
This study is testing whether different levels of muscle relaxation (called neuromuscular blockade) during breathing support can improve lung function in people with serious ARDS. It might help doctors choose the best relaxation level for patients on a breathing machine.
Nanjing, JiangsuAges 3 weeks–85 years - NCT07726953Recruiting
Full-course ECMO for moderate-to-severe ARDS
This trial tests a full-course strategy using a heart-lung bypass machine (ECMO) for people with moderate-to-severe acute respiratory distress syndrome (ARDS), a serious lung condition. The goal is to see if starting and continuing ECMO throughout treatment improves recovery.
BeijingAges 18 years+ - NCT06733168Recruiting
Electric imaging to guide breathing machine settings for ARDS
This trial tests whether using a special imaging technique (electrical impedance tomography) to set the breathing machine's pressure can improve oxygen levels and lung function in patients with moderate to severe ARDS, a serious lung condition.
HanoiAges 18 years+ - NCT07176624Recruiting
Early prone positioning and tube feeding in ICU
This study tests whether early prone positioning (lying on your stomach) and early tube feeding can help people with severe lung failure in the ICU recover faster. It's for adults with organ failure and severe ARDS who can safely be placed on their stomach.
Changchun, JilinAges 18 years+ - NCT07203781Recruiting
Breathing machine settings and their effect on breathing effort
This study is testing how different settings on a breathing machine affect your breathing effort and drive. It may help doctors find the best ventilator settings for patients with severe low oxygen levels.
Nijmegen, GelderlandAges 18 years+ - NCT07284888Recruiting
Prone positioning for ARDS patients on ventilators
This study looks at how placing patients on their stomach (prone positioning) affects those with serious lung failure (ARDS) who are on a breathing machine. It aims to learn more about the best practices for this treatment in the ICU.
Nanjing, JiangsuAges 18 years+ - NCT06477861Recruiting
Elastic power predicts ARDS severity and death risk
This study looks at a new way to predict how serious ARDS (a severe lung injury from pneumonia) is and the chance of death. Doctors will measure something called "elastic power" to see if it helps guide treatment for patients on a breathing machine.
Banhā, Al QalubeyahAges 18–65 - NCT07123025Recruiting
Partial pulp treatment for painful tooth decay
This study tests if removing only the top part of the damaged tooth nerve can save a deeply decayed molar. It is for people with moderate to severe toothache that doesn't stop, especially when lying down.
Rohtak, HaryanaAges 15–40 - NCT07316933Recruiting
Exercise with light blood flow restriction before knee replacement
This trial tests if a specific type of exercise, done with a cuff that lightly restricts blood flow to your leg, can help you get stronger and recover better while you wait for knee replacement surgery. The blood flow restriction is carefully controlled and adjusted during exercise, which may make the workout more effective.
Valencia, ValenciaAges 50–85 - NCT07370909RecruitingPhase 3
Oral LW402 for moderate-to-severe eczema
This trial tests an oral pill called LW402 for people with moderate-to-severe atopic dermatitis (eczema). It aims to see if the drug is safe and effective at reducing skin symptoms.
BeijingAges 18–75 - NCT07415044RecruitingPhase 2
Study of LY4268989 for moderate to severe ulcerative colitis
This study tests an investigational medication called LY4268989 for adults with moderate to severe ulcerative colitis (UC). It's for people who have tried other treatments without success. The goal is to see if the drug can reduce inflammation and improve symptoms.
Phoenix, ArizonaAges 18–80 - NCT05691218Recruiting
Early high-flow oxygen plus nebulized asthma medicine
This study tests whether giving fast, high-flow oxygen early—together with inhaled terbutaline via a vibrating mist—helps adults with moderate to severe asthma flare-ups in the emergency department. It aims to see if this approach improves breathing after initial treatment.
Poitiers, FranceAges 18 years+ - NCT06819878RecruitingPhase 3
Afimkibart for moderate to severe Crohn's disease
This study tests an experimental drug called afimkibart for people with moderate to severe Crohn's disease who haven't responded well to other treatments. The goal is to see if the drug can help control symptoms and reduce inflammation over time.
Dothan, AlabamaAges 16–80 - NCT07660835RecruitingPhase 2
A study of nemolizumab for babies with eczema
This trial tests a medicine called nemolizumab for babies aged 6 to 23 months with moderate to severe eczema. The goal is to see if it reduces itching and improves skin symptoms.
San Antonio, TexasAges 6 months–1.9 years - NCT07158242RecruitingPhase 3
Study of afimkibart for children with active ulcerative colitis
This study tests a new drug called afimkibart in children with moderate to severe ulcerative colitis who haven't responded well to other treatments. It aims to see how well the drug works and if it's safe for children.
Aurora, ColoradoAges 2–17
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Common questions
- Are there clinical trials for ards (moderate or severe)?
- Yes. Clin2 currently lists 1,504 recruiting ards (moderate or severe) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ards (moderate or severe) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ards (moderate or severe) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.