Arthroplasty clinical trials

Antimicrobial Wash During Shoulder Replacement

This study tests whether washing the surgical site with a special antimicrobial liquid after the incision can lower the risk of infection during shoulder replacement surgery. It may help people who are already planning a first-time shoulder replacement.

Study on Hi-Fatigue G Bone Cement in Knee or Hip Replacement

This study looks at how well a specific bone cement (Hi-Fatigue G) works in people who have had a knee or hip replacement. It aims to help doctors understand if this cement is a good option for holding the artificial joint in place.

Home rehab app for patients after shoulder replacement surgery

This trial tests a digital rehab program you can do at home after reverse total shoulder replacement. The goal is to see if an app-based exercise plan helps you recover safely and effectively.

Computer-assisted vs standard knee replacement study

This trial compares a computer-assisted technique to the standard method for total knee replacement. It aims to see if the computer-assisted approach leads to better clinical and functional outcomes.

Navigation vs robotic-arm assisted knee replacement

This study compares two different high-tech tools used during total knee replacement surgery: one that uses a navigation system (OrthoPilot) and one that uses a robotic arm (MAKO). The goal is to see if one method leads to better results. If you're having a total knee replacement, this trial could help your surgeon choose the best approach.

Ligament balancing in knee replacement

This trial tests a new method of balancing the ligaments during total knee replacement. If you are generally healthy and need a first-time knee replacement due to arthritis, you may be eligible.

Robotic vs custom knee replacement trial

This study compares two modern ways of doing knee replacement: robot-assisted surgery versus a custom-made implant tailored to your knee shape. It aims to see which approach leads to better recovery and function for people with osteoarthritis.

Comparing two types of plastic knee implants for replacement

This study compares two different types of plastic knee implants (polyethylene) used in total knee replacement surgery. The goal is to see which one works best for patients with knee arthritis.

Knee alignment study for total knee replacement

This study compares two different surgical techniques for total knee replacement to see which one leads to better knee movement and function. If you need a knee replacement due to arthritis, this trial may help find the best approach for your surgery.

Robotic vs augmented reality knee replacement

This study compares two advanced technologies for total knee replacement: a robot that uses a CT scan for guidance versus an augmented reality system that uses no scan. The goal is to see which approach leads to better outcomes for patients with osteoarthritis.

Cryoablation benefits in knee replacement surgery

This trial tests if a special cold treatment (cryoablation) can help reduce pain or improve recovery for people getting knee replacement surgery for arthritis. It might offer an extra option to feel better after the procedure.

Understanding long-term pain after hip or knee replacement

This study looks at people who still have moderate to severe pain months after a hip or knee replacement. The goal is to learn more about what causes this pain and how it feels, which could help improve future treatments.

Gait after hip replacement: comparing surgical approaches

This study compares how well people walk after three different types of hip replacement surgery for arthritis. It aims to see if one approach leads to a better walking pattern.

Study of osteoarthritis in hip and knee replacement patients

This study looks at why osteoarthritis happens in the hip and knee by studying tissue samples taken during joint replacement surgery. If you are already scheduled for a first-time hip or knee replacement and have osteoarthritis, you may be able to join.

Cold nerve treatment before knee replacement surgery

This trial tests a cold therapy on nerves before knee replacement to reduce pain. It may help you recover with less discomfort after surgery.

Nerve blocks for pain relief after knee replacement

This trial tests two types of numbing injections (nerve blocks) around the knee to help manage pain after total knee replacement surgery. The goal is to see if these injections reduce pain and improve recovery compared to standard pain treatment.

Brain Function Changes After Same-Day Hip or Knee Surgery

This study checks whether patients who have hip or knee replacement surgery and go home the same day experience any temporary changes in thinking or memory. Researchers want to understand how anesthesia and surgery affect the brain in the short term.

Nerve Block for Pain Relief During Knee Replacement

This study tests whether blocking a specific nerve in the knee can reduce pain and improve recovery after total knee replacement surgery. You would receive this nerve block alongside standard anesthesia to see if it helps you need fewer pain medications afterward.

Managing Pain After Knee Replacement Surgery

This study looks at how "rebound pain" (increased pain when pain medication wears off) affects long-term pain after total knee replacement. Researchers want to understand this connection and potentially improve pain management strategies for knee surgery patients.

Nerve blocks for pain after hip replacement

This trial compares two types of nerve blocks to see which better controls pain after hip replacement surgery and may reduce the need for pain medications. It helps determine the most effective pain management approach for recovery.

Comparing wear in two hip replacement sockets

This study compares how much two different types of dual-mobility hip sockets wear down over time in people having a hip replacement. If you are between 55 and 80 and scheduled for this surgery, you may be eligible to help doctors find out which implant lasts longer.

Total Shoulder Arthroplasty Multi-Center Registry

Ultrasound-Guided Knee Block Study for Knee Replacement

This study looks at whether using ultrasound to guide a numbing injection around the knee can improve pain control after knee replacement surgery. It aims to make recovery more comfortable.

Tranexamic Acid Pills After Hip Replacement

This study tests whether taking tranexamic acid (TXA) pills after hip replacement can reduce bleeding and the need for blood transfusions. It is for people having a first-time hip replacement due to severe arthritis who stay one night in the hospital.