Clinical trials
Arthroplasty clinical trials
Below are recruiting arthroplasty clinical trials, each written for real people, not researchers. We’re tracking 450 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05858086Recruiting
Physical therapy clearance before same-day knee or hip surgery
This study looks at whether you need to be “cleared” by physical therapy before going home the same day as knee (TKA) or hip (THA) replacement surgery. It may help determine the safest and most efficient discharge plan for patients who can go home with support right after surgery.
Baltimore, MarylandAges 18–90 - NCT04277416Enrolling by invitation
Testing a new hip replacement system and how patients do
This study follows people getting a primary total hip replacement using the Entrada hip system to see how long it lasts and how well it works. You may be offered this specific hip implant and would be followed through study visits to measure recovery and outcomes.
Portland, OregonAges 18–80 - NCT07869615Recruiting
Blood thinners after knee replacement surgery
This study compares two types of blood thinners to prevent blood clots after knee replacement surgery. It will help find which one works better and is safer for patients.
Tunis, Tunis GovernorateAges 18–80 - NCT07855341RecruitingPhase 4
Nerve block study for hip replacement pain relief
This study tests two different amounts of a numbing medicine injected around the hip nerves before hip replacement surgery, to see if adding a steroid helps reduce pain after surgery. It aims to improve pain control and recovery.
Cairo, Cairo GovernorateAges 50–70 - NCT04960098Recruiting
Survey after hip or knee replacement surgery
This study asks people who have had a hip or knee replacement to share how they’re doing over time. It’s testing whether patient-reported survey answers can help measure recovery and outcomes.
MilanAges 18 years+ - NCT05719935Recruiting
KinematX wrist replacement registry for people with wrist arthritis
This trial is a registry that follows people who get (or already had) a KinematX total wrist replacement. It collects health and recovery information to better understand outcomes for different wrist problems, like arthritis or certain bone alignment issues.
Loma Linda, CaliforniaAges 18–85 - NCT06127719Recruiting
Surgery wait time and knee replacement quality of life
This study looks at how waiting for knee replacement surgery affects your quality of life. It may help doctors understand how to improve care for people waiting for surgery.
Hoorn, North HollandAges 18–100 - NCT06108063RecruitingPhase 1/Phase 2
Losartan to prevent knee stiffness after replacement
This study tests whether losartan, a blood pressure medicine, can prevent excessive scar tissue (arthrofibrosis) after a total knee replacement. Participants receive losartan or a placebo for 6 months after surgery to see if it improves knee motion and reduces stiffness.
Vail, ColoradoAges 18 years+ - NCT05487274Recruiting
Shoulder arthritis surgery plan for specific shoulder bone alignment
This study compares two types of surgery for advanced shoulder osteoarthritis when the shoulder socket is turned backward more than 15 degrees. It aims to see which surgical approach works best for pain and function when the bone alignment issue can be corrected.
Ottawa, OntarioAges 65 years+ - NCT04801654Recruiting
Knee replacement study using a specific metal implant coating
This study looks at outcomes after a primary knee replacement using the GMK Sphere TiNb implant. It may help researchers learn how well this specific implant works and how patients do over time.
Milan, MIAges 18 years+ - NCT07838012Recruiting
Early home cycling after knee replacement surgery
This study tests whether starting gentle cycling at home soon after knee replacement surgery is safe and helpful. It aims to see if patients can use a stationary bike to speed up recovery.
Silkeborg, Central JutlandAges 18 years+ - NCT07812025Enrolling by invitation
Comparing keeping vs removing the labrum in hip replacement
This study compares two ways of handling the labrum (a rim of tissue around the hip socket) during a total hip replacement: keeping it or removing it. The goal is to see which approach leads to better outcomes for people with hip osteoarthritis.
Sandy Springs, GeorgiaAges 18 years+ - NCT07815145Recruiting
Comparing two nerve blocks for pain after hip replacement
This study compares two types of nerve blocks to see which provides better pain relief after hip replacement surgery. The blocks are given during surgery to reduce pain and may help you recover more comfortably.
Tanta, El-GharbiaAges 18–75 - NCT07798830Recruiting
Nerve block options for pain relief after hip replacement surgery
This study compares two types of nerve blocks to see which one provides better pain relief after hip replacement surgery. The blocks are given during the surgery to help reduce pain after the operation.
Tanta, El-GharbiaAges 18 years+ - NCT07790705Enrolling by invitation
Comparing two massage techniques after hip replacement
This study compares two types of massage therapy after hip replacement surgery to see which one works better for recovery. If you join, you will be randomly assigned to one of the two massage methods and will practice it at home for 6 weeks.
Cumming, GeorgiaAges 18 years+ - NCT06133920Recruiting
How long to immobilize after shoulder replacement for broken upper arm
This study compares different durations of immobilization (keeping the arm still) after a reverse total shoulder replacement for a broken upper arm. It aims to find the best approach for recovery.
Camden, New JerseyAges 60 years+ - NCT07771829Recruiting
Nerve blocks for pain after hip replacement
This trial compares two types of nerve blocks to see which better controls pain after hip replacement surgery and may reduce the need for pain medications. It helps determine the most effective pain management approach for recovery.
Wuhan, HubeiAges 18–70 - NCT05227924Recruiting
Testing safety and performance of a hip implant device type
This study checks how safe and well a specific brand of hip implant (SYMBOL range) works in people getting a total hip replacement. It may help by confirming the device performs as expected for primary or revision surgeries.
BeaumontAges 18 years+ - NCT07727551Recruiting
Nerve block before knee replacement for better recovery
This trial tests if a nerve block given a few weeks before knee replacement surgery can improve pain and function after the operation. It is designed for people who have certain risk factors that might make recovery harder.
BrusselsAges 18–60 - NCT07730216Recruiting
Ultrasound-Guided Knee Block Study for Knee Replacement
This study looks at whether using ultrasound to guide a numbing injection around the knee can improve pain control after knee replacement surgery. It aims to make recovery more comfortable.
Konya, KonyaAges 18 years+ - NCT07721415Enrolling by invitationPhase 4
Iodine drapes for shoulder replacement surgery
This trial is testing whether using iodine drapes during a first-time shoulder replacement reduces infection risk. It is for men who are planning this surgery.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07672808Recruiting
Pain relief after hip replacement without opioids
This study tests a combination of non-opioid pain medicines to reduce the need for opioids after hip replacement surgery. It aims to help patients manage pain with fewer risks of addiction and side effects.
Detroit, MichiganAges 18 years+ - NCT07672301RecruitingPhase 1/Phase 2
Comparing two anesthesia methods for knee replacement surgery
This trial compares total intravenous anesthesia (TIVA) with spinal anesthesia for people having a first-time total knee replacement who are expected to go home the same day. The goal is to see which method works better for recovery and comfort.
Chicago, IllinoisAges 18 years+ - NCT07665801Recruiting
Foot exercises after hip replacement surgery
This trial tests whether doing special foot exercises can improve recovery in people who have had a total hip replacement. It might help with walking and balance.
Ankara, AltındağAges 50–80
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Common questions
- Are there clinical trials for arthroplasty?
- Yes. Clin2 currently lists 450 recruiting arthroplasty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a arthroplasty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a arthroplasty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.