Clinical trials
Aspirin clinical trials
Below are recruiting aspirin clinical trials, each written for real people, not researchers. We’re tracking 136 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05868525RecruitingPhase 4
Compare two aspirin doses after blunt vessel injury
This trial tests whether taking a lower-dose aspirin (81 mg) works as well as a higher-dose aspirin (325 mg) to prevent stroke after a blunt injury that affects blood vessels in the neck/head. It may help some patients lower their stroke risk with the simplest, safest dose.
Loma Linda, CaliforniaAges 18 years+ - NCT03667326RecruitingPhase 2
Low-dose aspirin after severe preeclampsia
This Phase 2 study tests whether starting low-dose aspirin after delivery can help people who had severe preeclampsia. The goal is to see if this treatment is safe and beneficial in the weeks after birth.
New York, New YorkAges 18 years+ - NCT07525635RecruitingEarly Phase 1
Finding the Right Aspirin Dose During Pregnancy
This study helps doctors figure out the best dose of aspirin for pregnant people at high risk of preeclampsia (a serious pregnancy complication with high blood pressure). Researchers will check how aspirin affects your blood and baby to keep you both safe.
New York, New YorkAges 18–50 - NCT07431762RecruitingPhase 4
Aspirin vs. Warfarin after bioprosthetic valve surgery
This trial compares aspirin to warfarin in the first six months after receiving a bioprosthetic (tissue) heart valve. It aims to find which treatment better prevents blood clots without causing excessive bleeding.
OsakaAges 19 years+ - NCT07652723RecruitingPhase 1
How a new blood-clotting drug affects clotting with and without aspirin
This study tests an experimental drug (BAY3389934) to see how it affects blood clotting and if it's safe. It is given to healthy adults, alone and then with aspirin. It will help researchers understand how the drug works before testing in patients.
Miami, FloridaAges 18–55 - NCT07089862Recruiting
Indobufen vs aspirin for unruptured brain aneurysm treatment
This trial compares two anti-clotting drugs—indobufen and aspirin—to see which works better for people getting a stent or flow diverter for an unruptured brain aneurysm. The goal is to find which drug causes fewer bleeding or clotting problems.
Beijing, Beijing MunicipalityAges 18–75 - NCT07265466RecruitingPhase 1
Safety study of JP-1366 with common heart and blood medications
This trial tests how a new drug, JP-1366, interacts with several common heart and blood medications (clopidogrel, aspirin, atorvastatin, and apixaban) in healthy volunteers. It aims to see if the combination is safe and how the drugs affect each other in the body.
Seongnam-si, Gyeonggi-doAges 19–64 - NCT07117903Recruiting
Ketogenic diet follow-up study in Shanghai
This study follows up with people who completed the first Zhongshan Ketogenic Diet Study in 2025. It looks at the long-term effects of the diet. You may be eligible if you live in Shanghai and took part in the earlier study.
Shanghai, Shanghai MunicipalityAges 18–60 - NCT06738992RecruitingPhase 4
Early aspirin after mitral valve repair: safety and effectiveness
This study tests whether starting aspirin early after mitral valve repair is safe and effective compared to standard care. It's for adults who have had this heart surgery and have a low risk of bleeding or stroke.
Guangzhou, GuangdongAges 18–85 - NCT06935994RecruitingPhase 2
Aspirin for Fatty Liver Disease (MASLD)
This study tests whether aspirin can help people with MASLD, a type of fatty liver disease linked to conditions like diabetes and obesity. It aims to see if aspirin can improve liver health without causing harm.
Taichung, TaiwanAges 18 years+ - NCT06650488RecruitingPhase 4
Clopidogrel vs. Aspirin for Heart Protection in Blood Infection Patients
This trial tests whether switching from aspirin to clopidogrel better protects your heart and blood vessels during recovery from a serious staph infection in the blood. You may be eligible if you currently take aspirin for heart or stroke prevention.
Montreal, QuebecAges 18 years+ - NCT06588595RecruitingPhase 4
Switching Blood Thinners After Stent Placement
This study compares two ways to manage blood thinners after a stent. It tests whether switching from stronger drugs (prasugrel or ticagrelor) to clopidogrel is safe and effective for long-term heart protection.
Jacksonville, FloridaAges 18 years+ - NCT07719894RecruitingPhase 4
Preventing heart problems in type 2 diabetes with cilostazol and aspirin
This trial tests whether taking cilostazol and aspirin together can help prevent heart attacks, strokes, and other cardiovascular events in people with type 2 diabetes who have early signs of artery disease or metabolic syndrome. It aims to see if this combination is more effective than aspirin alone.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT04145258RecruitingPhase 3
Stronger TB treatment for meningitis to reduce deaths
This trial tests if giving a stronger combination of TB drugs for meningitis can save more lives. It's for patients who have been diagnosed with tuberculosis meningitis and have not yet started more than 5 days of TB treatment.
AbidjanAges 15 years+ - NCT04240834RecruitingPhase 4
Low-dose ticagrelor vs aspirin after heart stent placement
This study compares ticagrelor taken at a lower dose versus regular aspirin to help prevent future heart attacks in people who recently had a stent placed after acute coronary syndrome. You may qualify if you’re considered “high risk” for new blockages or clots and can take dual anti-platelet therapy for 12 months.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04295486RecruitingPhase 2
Low-dose aspirin to prevent blood clots after hip or knee surgery
This Phase 2 study tests the best dose of low-dose aspirin to help prevent dangerous blood clots after total hip or knee replacement surgery. If you’re at lower clot risk and can safely take aspirin, it may help reduce clot risk while you recover.
Miami, FloridaAges 19 years+ - NCT04356326RecruitingPhase 3
Aspirin to prevent complications in pregnancy with chronic high blood pressure
This trial studies whether taking acetyl salicylic acid (aspirin) during pregnancy can reduce problems caused by chronic high blood pressure. It focuses on pregnant people already known to have high blood pressure before or early in pregnancy.
BordeauxAges 18 years+ - NCT04381143RecruitingPhase 4
Aspirin to prevent problems in people on dialysis
This trial studies whether taking aspirin can reduce heart and clot-related complications in adults receiving long-term dialysis. It may help by improving blood clotting behavior, but it also requires that aspirin is safe for you.
Fuzhou, FujianAges 18 years+ - NCT04479072RecruitingPhase 4
Aspirin for preeclampsia during delivery
This trial tests whether taking aspirin during pregnancy around the time of delivery helps people with preeclampsia. You may be asked to take aspirin as part of a study plan, with monitoring to see how you do.
Chicago, IllinoisAges 18–45 - NCT04624295RecruitingPhase 4
Aspirin soon after certain bleeding stroke, after clot-busting therapy
This trial studies whether starting aspirin early is safe and helpful for people who, after clot-busting treatment for an ischemic stroke, develop a specific type of small brain bleeding called hemorrhagic infarction. You might benefit if your scan later shows this pattern of bleeding and you are not able to take blood-thinners or aspirin is safe for you.
HangzhouAges Any age - NCT05080946RecruitingEarly Phase 1
Aspirin with chemotherapy to improve ovarian tumor immune features
This early-phase study tests whether adding aspirin to standard neoadjuvant chemotherapy can change immune (anti-tumor) features inside ovarian, fallopian tube, or peritoneal tumors. It may help doctors better understand which patients respond and how aspirin could make treatment work better.
Tampa, FloridaAges 18 years+ - NCT05198960RecruitingPhase 3
Blood thinner drugs vs aspirin to prevent clot problems
This trial compares apixaban or rivaroxaban (blood thinners) against aspirin to prevent future clot-related complications in people with certain bone marrow diseases (PV, ET, or pre-PMF) that have a specific JAK2 mutation. It may help lower the risk of clots, but it also carefully considers bleeding risk.
AngersAges 18 years+ - NCT05320926Recruiting
Clopidogrel vs aspirin after heart stent treatment
This trial compares two blood-thinning medicines—clopidogrel and aspirin—after you have finished a short period of dual therapy following a special type of drug-eluting heart stent. It may help find which medicine works better and is safer for preventing future heart problems.
SeoulAges 19–84 - NCT05411718RecruitingPhase 2
Aspirin or naproxen to prevent cancer in Lynch syndrome
This trial tests whether daily aspirin or naproxen can “intercept” (stop) cancer from starting or coming back in people with Lynch syndrome who are currently cancer-free. Participants are randomly assigned to one of the two drugs, and neither the participant nor the team knows which one you’re taking.
Houston, TexasAges 18 years+
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Common questions
- Are there clinical trials for aspirin?
- Yes. Clin2 currently lists 136 recruiting aspirin studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a aspirin trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a aspirin trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.