Clinical trials
Autoimmune clinical trials
Below are recruiting autoimmune clinical trials, each written for real people, not researchers. We’re tracking 346 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07021209RecruitingPhase 1
GT719 for returning or hard-to-treat autoimmune neurological diseases
This trial tests a new antibody drug (GT719) for adults with autoimmune neurological diseases that came back or did not get better with standard treatment. It looks at how safe the drug is and how well it works.
Wuhan, HubeiAges 18–75 - NCT05925023Recruiting
Sirolimus for warm autoimmune hemolytic anemia after steroid failure
This trial studies sirolimus in adults with “warm” autoimmune hemolytic anemia (or Evans syndrome) when steroids have not worked or the anemia has returned. It may help control the immune attack on red blood cells, but there are specific safety checks for liver health and infections.
Beijing, Beijing MunicipalityAges 18–90 - NCT06811935Recruiting
PEDI Study for Kids with PANS or PANDAS
This study looks at children who may have PANS or PANDAS, conditions that can cause sudden changes in behavior or mood after an infection. It aims to better understand these conditions and improve care.
Lebanon, New HampshireAges 3–17 - NCT02889016Recruiting
Markers study for children with PANS and healthy controls
This study looks at physical, immune, and brain-related “markers” in children with PANS and compares them with healthy children. It may help doctors understand what is happening in PANS and how to recognize it more clearly early on.
Palo Alto, CaliforniaAges 4–18 - NCT07242092RecruitingPhase 4
Pausing methotrexate to boost pneumonia vaccine response
This study tests whether stopping methotrexate for a short time before getting the pneumonia vaccine (PCV20) helps your body build a stronger immune response. It is for people with autoimmune rheumatic diseases like rheumatoid arthritis or lupus whose disease is under control.
São Paulo, São PauloAges 18–100 - NCT05435547RecruitingPhase 4
Pre-surgery steroid medicine for autoimmune thyroid disease
This trial tests whether taking corticosteroids (anti-inflammatory medicines) before thyroid surgery is safe and helpful for people with autoimmune thyroid disease. It focuses on Graves’ or Hashimoto’s disease patients who are planning total thyroid removal.
Indianapolis, IndianaAges 18 years+ - NCT04239079Recruiting
Study of immune-related changes in Parkinson’s and Alzheimer’s
This study looks for “autoimmune-like” (immune-system) features in brain-related diseases such as Parkinson’s and Alzheimer’s, using genetic testing and other assessments. Results may help researchers understand what drives these conditions and who might be more likely to have immune-related changes.
New York, New YorkAges 55–90 - NCT07743242Recruiting
Study of hemolytic anemia in antiphospholipid syndrome
This study looks at how autoimmune hemolytic anemia (when the body attacks its own red blood cells) relates to antiphospholipid syndrome (a condition that increases blood clot risk). It aims to better understand this connection, which may help improve care for people with both conditions.
Al Khārjah, Kharga OasisAges 18 years+ - NCT07203404RecruitingEarly Phase 1
A study of a universal CAR-T cell therapy for autoimmune diseases
This trial tests a new treatment called RD06-05, which uses specially engineered immune cells to target and potentially reset parts of the immune system that are attacking your own body. It is being studied for several autoimmune conditions like lupus, vasculitis, kidney diseases, and more.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07085104RecruitingPhase 1
Study of ALLO-329 for lupus, myositis, or scleroderma
This trial tests a new one-time cell therapy (ALLO-329) made from donor cells to target and calm overactive immune cells in people with lupus, myositis, or scleroderma that hasn't improved with usual medications. It aims to see if this treatment is safe and can help reduce disease activity.
Phoenix, ArizonaAges 18–74 - NCT07413874Recruiting
Music therapy over video for depression and hormone disorder
This trial tests if telehealth music therapy can help adults who have both an endocrine autoimmune disease and depression. You'll join sessions from home using Zoom.
Boone, North CarolinaAges 18–65 - NCT06947460RecruitingPhase 1/Phase 2
CAR-T cell therapy for resistant lupus, sclerosis, and Sjögren's lung disease
This trial tests a special immune cell therapy (CAR-T cells targeting CD19 and BCMA) for people with lupus nephritis, systemic sclerosis, or Sjögren's-related lung blood vessel disease that hasn't improved with usual treatments. The goal is to see if this one-time cell infusion can calm the overactive immune system and improve symptoms.
Beijing, China,BeijingAges 10–65 - NCT07571681RecruitingPhase 2/Phase 3
Colchicine treatment for newly diagnosed thyroid inflammation
This trial tests whether colchicine, a medication that reduces inflammation, can help people recently diagnosed with Hashimoto's thyroiditis or subacute thyroiditis (two types of thyroid inflammation). Researchers want to see if it improves symptoms and thyroid function.
Al Mansurah, Dakahlia GovernorateAges 18–70 - NCT07295847RecruitingPhase 1
Study of AZD0120 for autoimmune diseases
This trial tests if a new medication, AZD0120, is safe for people with autoimmune diseases. It aims to help patients by targeting the immune system.
Tucson, ArizonaAges 18–75 - NCT07089121RecruitingPhase 1/Phase 2
Descartes-08 for young people with autoimmune diseases
This trial tests a new therapy called Descartes-08 for children, teens, and young adults with autoimmune conditions like lupus, myasthenia gravis, or dermatomyositis. It aims to see if it can help control moderate disease that hasn't responded well enough to other treatments.
Washington D.C., District of ColumbiaAges 12 years+ - NCT07727915Enrolling by invitation
Using genetics to predict chronic disease risk
This trial uses genetic information to help predict your risk of developing chronic diseases. It aims to create a platform that can identify health risks earlier so you can take preventive steps.
Medellín, AntioquiaAges 18–99 - NCT06570798RecruitingPhase 2
Testing Two Drugs for Lupus and Rheumatoid Arthritis
This trial tests two study drugs, inebilizumab and blinatumomab, for people with lupus (SLE) or rheumatoid arthritis (RA) that hasn't gotten better with standard treatments. It focuses on those with active disease, especially lupus-related kidney problems.
Scottsdale, ArizonaAges 18–75 - NCT06806592RecruitingPhase 3
Testing nerandomilast for lung scarring from rheumatic disease
This study tests a new medicine called nerandomilast to see if it can help people with lung scarring caused by autoimmune rheumatic diseases like rheumatoid arthritis or scleroderma. The goal is to slow down lung damage and improve breathing.
Birmingham, AlabamaAges 18 years+ - NCT06967701Recruiting
Building exercise habits for type 1 diabetes
This study helps adults with type 1 diabetes who don't exercise much build a safe and lasting exercise routine. You'll learn how to start moving more while managing your insulin and blood sugar levels.
New Haven, ConnecticutAges 30–65 - NCT02972801Recruiting
Freezing testicle tissue to protect future fertility
This study helps collect and freeze testicle tissue for people who must have surgery, chemotherapy, medicines, or radiation that could permanently harm fertility. You may join if you’re newly diagnosed or need planned treatment that threatens testicular function, and you agree to long-term follow-up.
Pittsburgh, PennsylvaniaAges Any age - NCT03648918Recruiting
Study family genetics in type 1 diabetes
This study looks at genetic patterns in families where someone has type 1 diabetes (an autoimmune condition). It may help researchers understand why type 1 diabetes happens and who is at risk.
Milwaukee, WisconsinAges 2 years+ - NCT03749538Recruiting
Brain stimulation test for autoimmune muscle weakness
This trial tests whether a noninvasive brain stimulation technique (through the scalp) can improve muscle weakness in people with certain autoimmune muscle diseases. It may help by changing brain signals that affect how muscles work.
São PauloAges 18–80 - NCT03848962Recruiting
Share leftover or collected samples for research
This study helps collect and share human samples (like blood or other specimens) so researchers can do new studies. It’s mainly about providing samples for research use, not testing a treatment on you.
Huntsville, AlabamaAges 1 month–89 years - NCT03953768Recruiting
Testing a new vagus nerve stimulator for gut and immune health
This study looks at what happens to your immune system and stomach/gut function after getting a vagus nerve stimulator (VNS) for the first time for epilepsy. It may help doctors understand whether the device benefits more than seizures.
Louisville, KentuckyAges birth–60 years
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Common questions
- Are there clinical trials for autoimmune?
- Yes. Clin2 currently lists 346 recruiting autoimmune studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a autoimmune trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a autoimmune trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.