Clinical trials
Biologics clinical trials
Below are recruiting biologics clinical trials, each written for real people, not researchers. We’re tracking 622 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05856370Recruiting
Study for follow-up of Medtronic spine or skull devices
This study checks how well certain Medtronic devices for the skull or spine are working in real-world care. If you’re getting one of these devices, you may be asked to do scheduled follow-up visits and assessments to confirm safety and performance.
Tucson, ArizonaAges 18 years+ - NCT05858411Recruiting
Biologic gum treatments added to non-surgical cleaning
This trial studies whether adding a biologic medicine to standard non-surgical gum (periodontal) treatment can improve deep gum pockets in certain bone defects. It may help people whose gum disease has specific “intrabony” defects, but you must meet several health and medication rules.
TiranaAges 18 years+ - NCT04232085RecruitingPhase 2
Stem cell transplant to rebuild immunity in genetic immune disorders
This Phase 2 trial tests a stem cell (bone marrow) transplant approach to restore bone marrow function and immune function in people with certain inherited immune problems. If you have one of these conditions and a suitable donor, the study may offer a path to rebuild blood and immune systems.
Baltimore, MarylandAges 4 months–50 years - NCT05812287Recruiting
Testing differences between two types of stomach cancer using lab data
This study compares two kinds of stomach cancer (near the upper stomach/“cardia” vs non-cardia) using special lab and genetic tests (“multiomics”). It may help doctors understand differences between these cancers and improve how they are diagnosed and treated.
Jinan, ShandongAges 18–75 - NCT05816850Recruiting
Advanced follicular lymphoma study using your lab samples
This study looks at advanced follicular lymphoma by analyzing samples of blood and tissue (and sometimes bone marrow) you may have already provided. It may help doctors understand your lymphoma better and improve future treatments.
AlessandriaAges 18 years+ - NCT00898235Recruiting
Collecting samples and health data for amyloidosis
This study collects blood and other samples, along with health information, from people who have—or might have—amyloidosis. It aims to improve understanding of the disease and support future treatments.
Boston, MassachusettsAges 18 years+ - NCT05787795Recruiting
Studying early risk signs for multiple sclerosis
This study looks at people who are at higher risk for multiple sclerosis (MS), to better understand early changes before MS is diagnosed. It may help doctors identify who is more likely to develop MS and how to monitor them sooner.
North Haven, ConnecticutAges 18 years+ - NCT05756985Recruiting
Providing fresh brain tissue to better understand glioblastoma
This study aims to improve understanding of glioblastoma (and gliosarcoma) by preserving live, usable brain-tissue samples during brain surgery. If you’re having repeat tumor surgery or your scans suggest these cancers, the study may ask to collect tissue for research.
Miami, FloridaAges 18 years+ - NCT05343286Recruiting
Personalized exercise plan for older adults
This study looks for health “signals” that can help tailor a physical activity program for people aged 60 and older. It may help decide which exercise approach works best for different individuals over time.
NiceAges 60 years+ - NCT05718895RecruitingPhase 1
ATG-022 for advanced solid tumors that have stopped responding
This early-phase study tests ATG-022 in adults with advanced or metastatic solid cancers that have progressed on standard treatment, cannot use standard treatment, or have no standard option. It may help by targeting cancer cells differently, and participation includes close monitoring and likely a biopsy.
AdelaideAges 18 years+ - NCT05675722RecruitingPhase 1
Vaginal reconstruction implant test for women born without a vagina
This Phase 1 study tests a vaginal implant/reconstruction device for people born with a missing or closed-off vagina. The goal is to check safety and how well the implanted vaginal tissue construct works over follow-up visits.
Winston-Salem, North CarolinaAges 15–45 - NCT04944030Recruiting
Study collects health data for metastatic lung cancer patients
This study collects medical information and test results from people with lung cancer that has spread (or cannot be cured with local treatment). It does not test a new drug; it helps researchers better understand patients’ health and care needs over time.
AngersAges 18 years+ - NCT05666739Recruiting
Store your sample for future research studies
This study collects and stores your biological samples so researchers can use them for future environmental health questions. You might join if you’re an adult, can travel for visits, and agree to have your samples stored for later use.
Research Triangle Park, North CarolinaAges 18–100 - NCT05639413Recruiting
Study of biology in people with BRAF V600E metastatic colon cancer
This study follows people with BRAF V600E–positive metastatic colorectal (colon) cancer to better understand how the cancer’s biology changes over time. It may help researchers learn which features to watch and how this cancer behaves after initial treatment.
AvignonAges 18 years+ - NCT05655390Recruiting
Study after a suicide attempt testing a new treatment link
This study looks at how well an approach helps people after a suicide attempt, and how certain measurements in the body and thinking relate to outcomes. You may be able to join if you’re an adult and can safely complete the study assessments.
Barcelona, BarcelonaAges 18 years+ - NCT05633875Recruiting
MRI study to better understand worsening in multiple sclerosis
This study uses detailed imaging (mostly MRI) to look for patterns that may explain why multiple sclerosis can worsen. It may help researchers understand the biology behind neurodegeneration and improve future care.
ParisAges 18 years+ - NCT05593640Recruiting
Thromboxane A2 and Knee Osteoarthritis Study
This trial is studying a substance called thromboxane A2 in people with knee osteoarthritis and joint swelling. It aims to help doctors better understand this condition and find new ways to treat it.
NiceAges 40 years+ - NCT05599347RecruitingPhase 2
Azithromycin before anti-TNF treatment for Crohn’s disease
This Phase 2 trial tests whether taking azithromycin (an antibiotic) before starting infliximab or adalimumab can reduce the chance your body rejects the anti‑TNF medicine. It may help some people get better and keep responding to treatment.
Haifa, Haifa DistrictAges 18 years+ - NCT05608148RecruitingPhase 1
GAIA-102 for relapsed or hard-to-treat childhood cancers
This Phase 1 study tests GAIA-102 in children and young adults whose cancer has returned or not responded to standard treatments. It aims to see if the treatment is safe and whether it may shrink tumors in certain pediatric solid cancers.
Fukuoka, FukuokaAges 1–24 - NCT05571579Recruiting
Collecting blood and tissue samples from confirmed brain tumors
This study collects biological samples from adults with a confirmed brain tumor. Samples may help researchers better understand brain tumors and improve future treatments.
Bron, RhôneAges 18 years+ - NCT05540561Recruiting
Testing and monitoring for nitrous oxide use
This study looks at how nitrous oxide (also called laughing gas) is detected and how health effects may show up over time. It may help doctors better diagnose problems early and track changes after use.
BéthuneAges 14–65 - NCT05476939RecruitingPhase 3
BIOMEDE 2.0 trial for DIPG and similar brainstem gliomas
This phase 3 study tests targeted treatments (ONC201 or everolimus) for children with DIPG or similar diffuse midline brain tumors, based on the tumor’s genetic markers. It aims to improve outcomes by matching treatment to the tumor biology and comparing approaches in a randomized way.
AarhusAges 6 months+ - NCT05458219RecruitingPhase 1
Testing an antibody-drug treatment for solid tumors
This Phase 1 trial studies a new cancer medicine (IBI343) that targets certain tumor cells to see how safe it is and how well it may work. You may be eligible if you have advanced, hard-to-remove cancers and your tumor has a specific marker called CLDN18.2.
Austin, TexasAges 18 years+ - NCT05421455Recruiting
Early vs delayed surgery for Crohn’s bowel narrowing
This study compares two timing choices for surgery in people with Crohn’s disease who have bowel narrowing (strictures) causing blockage symptoms. The goal is to see whether operating earlier leads to better control of symptoms and inflammation when other treatments haven’t worked.
Nanjing, JiangsuAges 18–60
Hear when a new Biologics trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for biologics?
- Yes. Clin2 currently lists 622 recruiting biologics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a biologics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a biologics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.