Clinical trials
Biologics clinical trials
Below are recruiting biologics clinical trials, each written for real people, not researchers. We’re tracking 620 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04396899RecruitingPhase 1/Phase 2
Stem cell heart patch for advanced heart failure
This early-phase study tests a lab-made heart tissue (“engineered myocardium”) placed surgically to help the heart work better in people with advanced heart failure. It mainly checks safety first, and also looks for signs the patch can improve heart function in selected patients.
Göttingen, Lower SaxonyAges 18–80 - NCT04476563Recruiting
Study liver injury from checkpoint cancer immunotherapy
This study looks at why some people develop liver inflammation after checkpoint inhibitor cancer treatment, called checkpoint inhibitor–induced liver injury (ChILI). It compares people with ChILI to similar cancer patients who are starting the same type of immunotherapy, to better understand and track these liver injury events.
NottinghamAges 18 years+ - NCT04458792Recruiting
Builds a cancer blood-and-biomarker database after sarcoma treatment
This study collects information and blood samples from adults with sarcoma who had surgery and possibly radiation. The goal is to build a large dataset that helps researchers understand sarcoma better and improve future care.
Montpellier, HeraultAges 18 years+ - NCT07724496Recruiting
H. pylori and stomach growth features study
This study looks at whether having H. pylori infection (a common stomach bacteria) and certain features of stomach growth can predict how early stomach cancer or pre-cancerous changes will behave and what your long-term outlook might be. You may be eligible if you are being treated with a camera-based removal procedure called endoscopic submucosal dissection (ESD).
Beijing, Beijing MunicipalityAges 18–80 - NCT07724470Recruiting
Stretching techniques for neck and arm pain
This study tests two types of stretching to see which one works better for neck pain that spreads into the arm. If you have had this pain for more than a month, this trial might help find a way to move better and feel less pain.
Lahore, Punjab ProvinceAges 30–60 - NCT07701486RecruitingPhase 1/Phase 2
Testing more frequent VCN-01 with standard chemo for new pancreatic cancer
This study tests a more frequent schedule of the experimental drug VCN-01 along with standard chemotherapy (nab-paclitaxel and gemcitabine) for people newly diagnosed with pancreatic cancer that has spread. The goal is to see if the virus-based therapy can help shrink tumors better.
Madrid, MadridAges 18 years+ - NCT04359394Recruiting
Rare severe pustular psoriasis family DNA study network
This study builds a large international registry of people with rare, severe pustular psoriasis to help doctors understand the genetics of the condition. You may be asked for information and, if you have eligible family members, DNA testing to learn how the disease runs in families.
MünchenAges 6 months+ - NCT04332692Recruiting
Check if a lung ultrasound helps evaluate discharge after heart failure
This study looks at whether doing lung ultrasounds can better assess people right before they leave the hospital after an acute heart failure flare. It may help doctors decide when someone is ready for discharge and tailor care to reduce risk after leaving.
Vandœuvre-lès-NancyAges 18 years+ - NCT04331639Recruiting
High-dose vitamin D for kids with IBD on biologic therapy
This trial studies whether giving a higher dose of vitamin D3 helps children and teens with inflammatory bowel disease (Crohn’s or ulcerative colitis) who have low vitamin D levels. Participants are already on biologic medicines and will be treated while monitoring blood (and safety) related to vitamin D.
Boston, MassachusettsAges 5–25 - NCT04214587Recruiting
Study of removed lung valves after treatment
This study looks at lung tissue taken out after a treatment that places a one-way lung valve to help breathing. They want to learn how the valve affects the airway and lung over time.
GroningenAges Any age - NCT04224038Recruiting
Healthy aging study for adults in France
This is a research study that builds a “bio-resource” (a platform that may store health information and biological samples) to help researchers understand healthy aging. It may help researchers find better ways to support long-term health over time.
ToulouseAges 30 years+ - NCT04207814Recruiting
Studying causes of repeated pregnancy loss in otherwise unexplained cases
This study looks for possible reasons why some pregnancies end in miscarriage or stillbirth when no clear cause is found. It involves tests and information from both partners, which may help guide future care for couples like yours.
BrestAges 18–40 - NCT04232085RecruitingPhase 2
Stem cell transplant to rebuild immunity in genetic immune disorders
This Phase 2 trial tests a stem cell (bone marrow) transplant approach to restore bone marrow function and immune function in people with certain inherited immune problems. If you have one of these conditions and a suitable donor, the study may offer a path to rebuild blood and immune systems.
Baltimore, MarylandAges 4 months–50 years - NCT07731737Recruiting
Biofeedback vs foam roller for knee osteoarthritis
This trial compares two non-surgical therapies—pressure biofeedback and foam rolling—to see which better reduces pain, improves muscle function, and boosts quality of life in people with early-stage knee osteoarthritis.
LahoreAges 45–65 - NCT04115267Recruiting
Registry study tracking side effects from radiation and medicines
This study follows people with cancer to better understand which treatments cause certain side effects when radiation is combined with targeted (molecular) medicines. Your participation may help doctors predict and manage side effects more safely in the future.
Montreal, QuebecAges 18 years+ - NCT04103567Recruiting
Testing stool and bacteria clues for poor rectal cancer response
This study looks at stool samples to see whether gut bacteria or other microbes help explain why some rectal cancers respond less well to treatment given before surgery. If you have mid or lower rectal cancer and are planning pre-surgery treatment, your information and stool sample may help researchers improve how treatment is chosen.
Montpellier, HéraultAges 18 years+ - NCT04119102RecruitingPhase 4
Duobrii added to biologic treatment for plaque psoriasis
This trial tests whether adding Duobrii (a prescription psoriasis lotion) on top of your current biologic treatment helps improve plaque psoriasis. It includes adults whose psoriasis is in a moderate range and who have already been on a biologic for at least 24 weeks.
East Windsor, New JerseyAges 18 years+ - NCT07731724Recruiting
Barre and Tupler exercises for diastasis recti
This trial studies two types of core exercises (barre-based and Tupler technique) to see which works better for strengthening the core, closing the tummy gap, and improving pelvic floor function in women with diastasis recti after childbirth.
Lahore, Punjab ProvinceAges 18–40 - NCT04014348Recruiting
Study links neighborhood stress to heart health in women
This study looks at whether stressful neighborhood conditions are connected to heart-health blood markers and everyday health behaviors. It mainly enrolls healthy women in Washington, DC to help researchers understand how environment may affect cardiovascular risk.
Bethesda, MarylandAges 19–45 - NCT03894917Recruiting
Study blood and imaging features in older adults with liver cancer
This study looks at what liver cancer is like in newly diagnosed people who are older and whose cancer cannot be removed by surgery. It may help doctors better understand disease behavior and how treatments may work and affect the body.
San Antonio, TexasAges 18 years+ - NCT04005638Recruiting
Biobank for people with autoimmune blood cell disorders
This study collects and stores biological samples (a “biobank”) from people with autoimmune cytopenia, so researchers can learn more about the condition. If you qualify, your samples may help future studies and improve care, and it’s based on voluntary consent.
PessacAges 18 years+ - NCT03932786Recruiting
Study of health and wellbeing after retinoblastoma treatment
This study looks at long-term health outcomes—how patients are doing physically and in daily life—after treatment for retinoblastoma. It may help doctors understand what support or follow-up care could be most helpful after treatment.
Chicago, IllinoisAges Any age - NCT04018118Recruiting
Study of the course of high eosinophil blood disease
This study follows people with long-term high eosinophils (a type of white blood cell) and related conditions to learn how the illness changes over time. It helps doctors understand patterns of organ involvement and outcomes, which may improve future care.
LilleAges Any age - NCT03968913RecruitingEarly Phase 1
Biologic shot to prevent knee arthritis after ACL injury
This early-phase trial tests a biologic medicine (anakinra) given after an ACL injury to try to prevent or reduce later osteoarthritis (wear-and-tear arthritis). It enrolls young adults who recently tore their ACL and are planning a specific type of ACL reconstruction.
Los Angeles, CaliforniaAges 18–35
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Common questions
- Are there clinical trials for biologics?
- Yes. Clin2 currently lists 620 recruiting biologics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a biologics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a biologics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.