Clinical trials
Bipolar Disorder I or II clinical trials
Below are recruiting bipolar disorder i or ii clinical trials, each written for real people, not researchers. We’re tracking 2,350 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07759128RecruitingPhase 3
Test of a new anxiety medication for adults with generalized anxiety disorder
This study tests a new medicine (SEP-363856) for adults with generalized anxiety disorder to see if it reduces anxiety symptoms and is safe. It may help if other treatments haven't worked well.
Tucson, ArizonaAges 18 years+ - NCT07759895RecruitingPhase 2
Two-drug treatment for negative symptoms of schizophrenia
This trial tests two medicines, deferiprone and N-acetylcysteine, taken together to see if they improve negative symptoms of schizophrenia, such as lack of motivation or pleasure. It aims to find a new option for people who still have these symptoms despite their current antipsychotic treatment.
JerusalemAges 18–40 - NCT07763977Enrolling by invitation
Vitamin D and iron study for obsessive-compulsive disorder
This study tests whether vitamin D and iron levels affect brain function linked to self-control in people with OCD. It may help find new ways to improve treatment.
Guangzhou, GuangdongAges 14–45 - NCT07758010Recruiting
Brain stimulation for treatment-resistant depression
This study tests a type of brain stimulation called cTBS (continuous theta burst stimulation) applied to a specific part of the brain (the precuneus) to see if it helps with treatment-resistant depression. It aims to provide a new option for people who haven't found relief from standard treatments.
Belmont, MassachusettsAges 18 years+ - NCT07754253RecruitingPhase 1
Green tea extract for gum disease treatment
This trial tests a green tea extract (EGCG) as an add-on to standard gum disease treatment, delivered locally to the gums. It aims to see if this natural compound can help improve gum health more effectively than standard care alone.
Al Mansurah, Dakahlia GovernorateAges 25–60 - NCT07754240Recruiting
Stent graft for abdominal aortic aneurysm
This trial tests a new stent graft device for treating abdominal aortic aneurysms. The device is placed inside the aneurysm to reinforce the artery and prevent rupture, which may help people who are candidates for this minimally invasive procedure.
PlevenAges 18–80 - NCT07755410RecruitingPhase 2
Investigational ADHD treatment for adults
This study tests an investigational medication for adults with attention deficit hyperactivity disorder (ADHD). It aims to see if this new drug helps reduce ADHD symptoms compared to a placebo.
Little Rock, ArkansasAges 18–65 - NCT07748091Recruiting
Brain wave and inflammation markers in shock therapy for depression
This study looks at brain wave patterns and markers of inflammation in people with depression that hasn't improved with other treatments and who are receiving electroconvulsive therapy (ECT, also known as shock therapy). The goal is to understand how these markers might relate to how well ECT works.
Istanbul, BakırköyAges 18–60 - NCT07738770Recruiting
Comparing two numbing techniques for pain relief after mastectomy
This trial tests two different numbing injections to see which one works better for pain after breast cancer surgery. If you are having a mastectomy, you may be able to join and help find a better way to manage pain.
Jakarta, DKI JakartaAges 18–60 - NCT07738952RecruitingPhase 1/Phase 2
Sivelestat for neuromyelitis optica spectrum disorder relapses
This study tests a drug called sivelestat for people with neuromyelitis optica spectrum disorder (NMOSD) who are having a relapse. The drug may help reduce damage during the relapse and improve recovery.
FukuokaAges 18 years+ - NCT07733167RecruitingPhase 3
Epinephrine injection during prostate surgery for large prostates
This study tests whether injecting a drug called epinephrine into the prostate during surgery can improve outcomes for men with large prostates. It aims to reduce bleeding and make the surgery safer and more effective.
Banhā, Qalyubia GovernorateAges 40 years+ - NCT06630065Recruiting
Ketamine study for depression using brain scans
This trial uses brain scans to understand how ketamine affects negative emotions in people with depression. It may help explain why ketamine works and who benefits most.
Paris, ParisAges 18 years+ - NCT05644301RecruitingPhase 3
Blood-marker guided add-on treatment for major depression
This study tests whether doctors can choose the best add-on immune-related treatment for people with major depressive disorder by using inflammation blood tests. It’s meant for people whose depression has not improved enough with their current antidepressant.
Duffel, AntwerpenAges 18–65 - NCT06644352Recruiting
Comparing right vs. left chest surgery for junction cancer
This study compares two surgical approaches (right side of the chest vs. left side of the chest) for removing a certain type of cancer at the gastroesophageal junction. It aims to find which approach leads to better outcomes.
BeijingAges 18–80 - NCT07699445RecruitingPhase 4
Lumateperone for weight and mood in bipolar depression
This study tests if lumateperone, a medication for bipolar depression, can also help with weight and aging in people with obesity. You may qualify if you have bipolar I depression and a body mass index (BMI) over 30.
Boston, MassachusettsAges 18–65 - NCT07701616Recruiting
Digital mindfulness therapy for obsessive-compulsive disorder
This study tests a smartphone-based mindfulness program to help people with obsessive-compulsive disorder (OCD) reduce their symptoms. If you have OCD and are between 12 and 65 years old, you may be able to join.
Changsha, HunanAges 12–65 - NCT07682207Recruiting
Accelerated brain stimulation for PTSD and depression
This study tests an accelerated form of brain stimulation called iTBS to see if it can help people with both PTSD and depression. It may be a good option if you have not found enough relief from your current treatments.
London, OntarioAges 18 years+ - NCT04221997RecruitingPhase 4
Sertraline study for anxious children and teens
This trial tests whether sertraline (an anti-anxiety medicine) helps children and teens with generalized, separation, and/or social anxiety disorders. It also includes healthy children/teens for comparison so researchers can better understand safety and symptoms over time.
Cincinnati, OhioAges 8–17 - NCT07676695Recruiting
Jaw Device and Sound Waves for Class II Malocclusion
This trial tests a special jaw repositioning device (Twin-Block) combined with low-intensity sound waves (LIPUS) to help treat a class II malocclusion (when the lower jaw is set back) in children and teens. It aims to improve jaw alignment and joint outcomes.
CairoAges 10 months–1.2 years - NCT07666776Recruiting
Attention training for social anxiety: a controlled trial
This study tests whether a simple computer exercise that trains your attention away from threat can reduce social anxiety, compared to a placebo (neutral) version. It's for adults with social anxiety disorder and takes place at Tel Aviv University.
Tel AvivAges 18–65 - NCT05356520Recruiting
Which operation is best for Siewert type II stomach cancer
This trial compares different surgical approaches for removing Siewert type II cancer at the esophagus–stomach junction. It aims to find which operation works best for people who can have the tumor removed.
Xi'an, ShaanxiAges 18–75 - NCT06677866Recruiting
Group therapy for teens with Fragile X or autism
This trial tests if group cognitive behavioral therapy (CBT) can help teens with Fragile X syndrome or autism spectrum disorder improve social and emotional skills. It looks at how teens with these conditions respond to a structured group program.
RomeAges 13–19 - NCT07646509Recruiting
Mobile app to reduce physical symptoms from stress
This study tests a smartphone app designed to help people with somatic symptom disorder—a condition where stress and emotional distress cause ongoing physical symptoms that don't have a clear medical explanation. The app sends you check-ins and guidance throughout your day to help reduce these symptoms.
Vienna, State of ViennaAges 18–65 - NCT07638553RecruitingPhase 3
Psilocybin to prevent alcohol relapse with depression
This study tests whether psilocybin (a psychedelic compound) can help people with severe alcohol use disorder stay sober longer, especially if they also have depression. Participants receive guided psilocybin sessions alongside counseling to reduce the risk of returning to heavy drinking.
BayonneAges 18 years+
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Common questions
- Are there clinical trials for bipolar disorder i or ii?
- Yes. Clin2 currently lists 2,350 recruiting bipolar disorder i or ii studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bipolar disorder i or ii trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bipolar disorder i or ii trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.