Clinical trials
Bipolar clinical trials
Below are recruiting bipolar clinical trials, each written for real people, not researchers. We’re tracking 241 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06823024Enrolling by invitation
Using speech patterns to predict treatment response in depression, PTSD, or bipolar disorder
This study tests if a computer algorithm can analyze your speech to predict how well you will respond to treatments like TMS or Spravato. It aims to create a simple tool that helps doctors choose the right treatment for you.
Sunnyvale, CaliforniaAges 18–68 - NCT06792175Enrolling by invitation
Using speech to detect mental health conditions
This study uses a computer program to listen to your speech and see if it can help detect mental health or neurodevelopmental conditions. It may help find new ways to diagnose conditions like ADHD, anxiety, depression, and others earlier.
Brookline, MassachusettsAges 13–60 - NCT04946916Recruiting
Testing blood/brain marker levels and thinking problems in psychiatric illness
This study looks at neurofilament light (a brain/nerve injury marker) and how it relates to thinking and memory problems in people with certain psychiatric conditions. It may help researchers understand brain changes and cognitive impairment, which could guide better diagnosis in the future.
BronAges 45–80 - NCT06759194Recruiting
Comparing Two Laser Surgeries for Large Prostate
This trial compares two minimally invasive surgeries to treat a very enlarged prostate (BPH) when medicines are not enough. It aims to see which approach gives better relief for men with large prostates.
AsyutAges 50 years+ - NCT06758414Recruiting
CBT for chronic pain in veterans with serious mental illness
This trial tests a type of talk therapy called Cognitive Behavioral Therapy for Chronic Pain, designed for veterans with serious mental illness. It aims to help you manage back pain and improve your quality of life.
Baltimore, MarylandAges 18 years+ - NCT06740383Recruiting
Study of early psychosis and treatments
This study looks at people who have had psychosis for less than 4 years to understand how their symptoms change over time and how they respond to treatment. By using brain scans and other tests, researchers hope to find better ways to personalize care for early psychosis.
Hartford, ConnecticutAges 18–40 - NCT06743711Recruiting
Heart fitness in severe mental illness study
This study checks how fit your heart and lungs are if you have a serious mental illness like schizophrenia or bipolar disorder. It aims to see if fitness can help improve health and well-being.
Glostrup MunicipalityAges 18–45 - NCT06700902Recruiting
Support program for college students with mental health challenges
This study tests a program called 'Taking Action' to help college students with serious mental illnesses manage their health and daily life. If you're a student with a mental health condition, you may be able to join to learn new coping skills through group education.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06649357Recruiting
Comparing two surgeries for enlarged prostate: electric vs. laser
This study compares two common surgeries for an enlarged prostate: a traditional electric loop resection and a laser enucleation (Moses HoLEP). The goal is to see if one offers better symptom relief and fewer side effects.
Santiago de Compostela, A CoruñaAges Any age - NCT06641726Recruiting
Global database linking genetics and health records for mental illness
This trial is building a research database that combines genetic information and long-term health data to improve personalized treatment for serious mental illness. You may be eligible if you have been diagnosed or treated for depression, bipolar disorder, schizophrenia, or dementia.
Oxford, OxfordAges 18–110 - NCT06624462Recruiting
Meta Care Clinic for weight and health in severe mental illness
This study tests a special clinic that helps people with schizophrenia or bipolar disorder manage their weight and metabolic health while taking antipsychotic medication. It focuses on improving overall health with practical support.
Glostrup Municipality, Capital RegionAges 18–45 - NCT06586164Recruiting
Rehabilitation research for veterans with serious mental illness
This study is testing a new rehabilitation program for veterans with serious mental illness, like schizophrenia, bipolar disorder, or PTSD. If you join, you will help researchers see if this program improves daily functioning and quality of life.
San Diego, CaliforniaAges 18–83 - NCT06594926RecruitingPhase 2
Bipolar androgen therapy for prostate cancer without metastases
This trial tests a treatment called bipolar androgen therapy for men with prostate cancer that has not spread to other parts of the body and is still growing despite taking darolutamide. The goal is to see if this therapy can help control the cancer.
Garran, Australian Capital TerritoryAges 18 years+ - NCT06558201Enrolling by invitation
Open-label extension for completers of earlier study
This trial is for people who finished a 12-week study (NCT06221852) and still meet its original requirements. It offers continued access to the study treatment.
Belmont, MassachusettsAges 18–45 - NCT06529029RecruitingPhase 2/Phase 3
Comparing new low-pulse ECT to standard ECT for depression
This trial tests a new type of seizure therapy (low amplitude pulse seizure therapy) against the standard ultra-brief right unilateral ECT for people with severe depression, including those with suicidal thoughts. The goal is to see which treatment works better.
Grand Rapids, MichiganAges 18–90 - NCT04296604Recruiting
tDCS brain stimulation to improve thinking and mood
This study tests whether a non-surgical brain stimulation called tDCS can improve “executive function,” which means skills like planning, focus, and decision-making. It is designed for people with several mental health and substance-use conditions, and it may help you if those skills are affected by your diagnosis.
Boston, MassachusettsAges 18–65 - NCT06408012Recruiting
Master platform for mood disorder trials
This trial creates a flexible platform to test new treatments for mood disorders like bipolar disorder and depression. It also includes healthy volunteers as a comparison group.
Calgary, AlbertaAges 16 years+ - NCT06315582Recruiting
Surgery for uterine septum
This study looks at a surgical approach to remove a uterine septum (a wall of tissue inside the uterus) that is larger than 1 cm. It may help people with this condition who are between 20 and 44 years old.
Chicago, IllinoisAges 22–44 - NCT06313918Recruiting
Exercise therapy for schizophrenia and bipolar disorder
This study tests whether an exercise program can help people with schizophrenia or bipolar disorder. It aims to see if physical activity improves mental health and overall well-being.
BergenAges 16 years+ - NCT06289478Recruiting
Tranexamic acid for bleeding during hip replacement surgery
This study tests whether a medicine called tranexamic acid (TXA), given as a shot into the hip joint or as a soak on the skin, can reduce bleeding during hip replacement surgery. It is for people over 60 who broke their hip from a simple fall and need a cementless hip replacement.
Bangkok, BangkokAges 60 years+ - NCT06273683Recruiting
Comparing two tubal removal methods during C-section
This study compares two ways of removing the fallopian tubes (salpingectomy) during a planned C-section for permanent birth control. You and your baby will get the same standard care, and the study helps find which technique works best.
Falls Church, VirginiaAges 21 years+ - NCT06188754Recruiting
Healthy lifestyle program for bipolar disorder and sleep issues
This study tests a healthy lifestyle program (including diet changes) for people with bipolar disorder who have sleep problems. It aims to improve sleep and overall well-being by teaching new habits.
Berkeley, CaliforniaAges 18–65 - NCT06107764Recruiting
Brain stimulation study for thinking and memory in psychosis
This trial tests whether a non-invasive brain stimulation technique (rTMS) can improve thinking and memory in people with psychosis. It involves MRI scans and several study visits at McLean Hospital.
Belmont, MassachusettsAges 18–55 - NCT06100705RecruitingPhase 2
Immunotherapy plus testosterone for advanced prostate cancer
This study combines an immunotherapy drug called sipuleucel-T (which boosts your immune system to fight cancer) with a high-dose testosterone treatment called bipolar androgen therapy. The goal is to see if this combination can help men with advanced prostate cancer that is not responding to usual hormone therapy.
New Haven, ConnecticutAges 18 years+
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Common questions
- Are there clinical trials for bipolar?
- Yes. Clin2 currently lists 241 recruiting bipolar studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bipolar trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bipolar trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.