Clinical trials
Blood Donors clinical trials
Below are recruiting blood donors clinical trials, each written for real people, not researchers. We’re tracking 40 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06809010Recruiting
Blood storage study for group O donors
This study looks at how storing whole blood from group O donors affects blood cells and inflammation. It may help improve blood transfusions for patients.
Saint-EtienneAges 18–65 - NCT06183632Recruiting
Lipid study in healthy blood donors
This research study looks at tiny particles in the blood called microparticles and their fat content. It aims to understand these particles in healthy people, which helps in future research on diseases.
DijonAges 18 years+ - NCT05581745Recruiting
Testing a lung transplant approach for certain blood type O patients
This study looks at lung transplants for people getting their first transplant who are blood type O and have low levels of antibodies that may react to donor tissue. It may help doctors choose the safest donor-recipient match for these patients.
Toronto, OntarioAges 18 years+ - NCT04806347RecruitingPhase 1
Stem cell transplant using a half-matched donor for children and young adults
This trial studies a type of stem cell transplant (bone marrow transplant) that uses a donor who is only half-matched to the patient, often a parent or sibling. It is for children and young adults with certain blood diseases, including sickle cell disease, thalassemia, bone marrow failure, and immune disorders. The transplant aims to replace the diseased blood-forming cells with healthy ones from the donor.
Madison, WisconsinAges 3 months–25 years - NCT03970096RecruitingPhase 2
Reduce graft-versus-host disease after stem cell transplant
This Phase 2 study tests ways to lower the risk of graft-versus-host disease (GVHD), a serious complication after an allogeneic stem cell transplant from a matched donor. It is for people with acute leukemia or MDS who are going to receive intensive conditioning therapy, aiming to improve safety while keeping the transplant effective.
Tampa, FloridaAges 1–60 - NCT07207629Enrolling by invitation
Heart ultrasound study in healthy blood donors
This study uses a heart ultrasound (echocardiography) to see how the heart changes when healthy volunteers donate blood. If you're a healthy adult who can donate blood, you may help researchers understand more about blood donation's effect on the heart.
Nîmes, OccitanieAges 18–40 - NCT05693701Recruiting
Lifestyle and study program for blood donors with high cholesterol
This study tests a multicomponent program for people who donate blood and have high cholesterol that fits familial hypercholesterolemia criteria. It may help lower cholesterol, but you must not already be on cholesterol-lowering medicines.
Dallas, TexasAges 18–75 - NCT05628974Recruiting
Healthy adults can donate blood for platelet testing
This study looks at how platelets work and checks blood markers using donations from healthy volunteers. It may help researchers design future platelet-related treatments and better tests.
Cleveland, OhioAges 18–65 - NCT03971669RecruitingPhase 4
Blood donor study testing safety of donating in health
This trial studies people who donate blood and checks what happens in your body after donation, focusing on safety and measurements in lab tests. You may be able to join if you are healthy and pass screening labs and health history checks.
Baltimore, MarylandAges 18 years+ - NCT00001846Recruiting
Blood donation for medical research use
This study collects blood from healthy volunteers to be used in laboratory research. Your blood helps scientists study diseases and test new treatments in the lab.
Bethesda, MarylandAges 18–100 - NCT06859424RecruitingPhase 2
Testing a new GVHD prevention method after donor stem cell transplant
This trial tests a new way to prevent graft-versus-host disease (a common side effect of stem cell transplant) using a drug called cyclophosphamide after transplant. It is for adults with certain blood cancers who need a transplant from a partially matched unrelated donor.
Birmingham, AlabamaAges 18–66 - NCT00900497Enrolling by invitationPhase 1/Phase 2
Donor white blood cells to treat solid tumors
This Phase 1/2 study tests whether donated white blood cells (granulocytes) from healthy donors can help treat solid cancers that cannot be cured or have stopped responding to standard treatments. The goal is to see safety first, and then whether the treatment can shrink or control tumors.
Boynton Beach, FloridaAges 18 years+ - NCT06784440Recruiting
Finding noninvasive markers of graft injury after heart transplant
This study looks for noninvasive markers (like blood or urine tests) that can show if a heart transplant is being injured. It aims to make monitoring safer and easier for children and adults with congenital heart disease who have had a transplant.
BolognaAges Up to 44 years - NCT06569082Recruiting
Stem cell boost for poor graft function
This study tests whether giving extra stem cells from your original donor can help your blood cell counts recover after a transplant. It is for people whose new immune system has not fully engrafted or whose counts are dangerously low.
New York, New YorkAges 18 years+ - NCT03016806Recruiting
Umbilical cord blood transplant from unrelated donors
This trial studies transplanting healthy blood-forming cells from an umbilical cord blood donor who is not related to you. It may help people with certain blood cancers, immune disorders, or other serious diseases when a standard transplant plan is needed.
Rochester, New YorkAges 2 months–75 years - NCT06508138Enrolling by invitationPhase 1
HPV vaccine study for healthy relatives of patients
This trial tests two experimental vaccines to boost the immune system against HPV 16. Healthy relatives of patients with HPV 16 cancer receive the vaccines, then donate blood cells for research.
Baltimore, MarylandAges 18–70 - NCT06141902Enrolling by invitation
Herbal tea for stem cell donor well-being
This study tests whether a special herbal tea (Jing Si Herbal Drink) can help people who donate stem cells feel better physically and emotionally. It is for healthy stem cell donors who are willing to drink the tea as part of the study.
Hualien CityAges 20–55 - NCT06840756RecruitingPhase 4
Does donor-patient sex matching improve blood transfusion outcomes?
This trial tests whether giving ICU patients blood from a donor of the same sex (male-to-male or female-to-female) leads to better recovery compared to mismatched transfusions. The goal is to see if matching donor and patient sex makes a difference in how well patients do.
Hamilton, OntarioAges 18 years+ - NCT04678401RecruitingPhase 1
Trial tests transplant using a half-matched donor for high-risk leukemia
This Phase 1 trial tests a special bone marrow transplant using a related “half-matched” donor (haploidentical), without a specific immune-suppressing medicine (“IS-free”). It’s for adults with certain high-risk AML or MDS to see if this approach can improve control of the disease while tracking safety.
Boston, MassachusettsAges 18–75 - NCT01553214RecruitingPhase 4
Blood donation study to improve white blood cell collection
This study tests a better way to collect white blood cells from healthy people who donate blood. It may help improve how reliably and safely white blood cells are collected for research or future treatments.
Bethesda, MarylandAges 18–75 - NCT00785525RecruitingPhase 3
G-CSF to collect stem cells from unrelated donors
This Phase 3 study tests using filgrastim (a medicine that helps stem cells leave the bone marrow) to collect stem cells from unrelated donors for transplant. It focuses on donor safety and whether this collection method works well enough for transplantation.
Boca Raton, FloridaAges 18–60 - NCT07285668Recruiting
Special donor immune cells after stem cell transplant for high-risk blood cancers
This study tests whether giving specially treated donor immune cells after a stem cell transplant can help prevent relapse in patients with high-risk blood cancers. You would get a stem cell transplant from a relative, followed by an infusion of donor cells that have been processed to reduce the risk of graft-versus-host disease.
Madison, WisconsinAges 18–80 - NCT00001620Enrolling by invitation
NIH screening to see which blood studies fit you
This study is a general screening step at the NIH Clinical Center to check whether you might qualify for other NHLBI research protocols. It helps match you (or a donor/healthy volunteer) to the right study and confirms you can consent to participate.
Bethesda, MarylandAges 2–100 - NCT06875232Enrolling by invitation
Comparing CT and MRI scans for live liver donors
This study looks at how well CT scans and MRI scans (MRCP) show the blood vessels in the liver before a living donor liver donation. It aims to find out which scan is better at planning the surgery.
Rotterdam, South HollandAges 18–60
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Common questions
- Are there clinical trials for blood donors?
- Yes. Clin2 currently lists 40 recruiting blood donors studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a blood donors trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a blood donors trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.