Clinical trials
Brain Diseases clinical trials
Below are recruiting brain diseases clinical trials, each written for real people, not researchers. We’re tracking 328 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06973018Enrolling by invitation
Online cognitive rehab for mild memory problems
This trial tests an online program to help people with mild to moderate cognitive problems after a brain injury or nervous system disease improve their thinking skills. It is for Swedish speakers with internet access.
Stockholm, Stockholm CountyAges 18 years+ - NCT06947876Recruiting
PUFFINS brain health study for adults 50+
This study looks at how small blood vessel changes in the brain (called 'small vessel disease') affect thinking and memory over time. It may help us understand how to keep brains healthy as we age. If you are 50 or older and do not have any memory concerns, you might be able to join.
AberdeenAges 50 years+ - NCT06203626Recruiting
Portable MRI for brain imaging at the bedside
This study is testing a new, portable MRI machine that can be used right at your bedside. It aims to see if it can take clear pictures of the brain for people with strokes, brain conditions, or symptoms of a brain problem.
Bethesda, MarylandAges 3–99 - NCT05658965Recruiting
EEG monitoring after early heart surgery in infants
This study looks at whether early brain-wave testing (EEG) around the time of heart surgery in very young babies can predict later learning and development issues. It may help doctors identify children who need extra support sooner.
Lille, Hauts-de-FranceAges 1 day–1 year - NCT05400174Recruiting
How blood pressure changes affect thinking and brain flow in Parkinson’s
This study measures how your blood pressure affects thinking skills and how blood flows in the brain in people with Parkinson’s. It may help researchers understand what blood-pressure changes could mean for cognition in Parkinson’s.
San Diego, CaliforniaAges 50 years+ - NCT03153670Recruiting
Brain scan study for people with deep brain stimulators
This study uses a 3‑tesla MRI (a type of detailed brain scan) in people who have deep brain stimulation (DBS) electrodes. The goal is to improve understanding of how the brain works; the scan is not meant to provide direct treatment benefit.
Toronto, OntarioAges 18–85 - NCT02649985RecruitingPhase 1/Phase 2
PET brain scan study for several brain and mood conditions
This early-phase study uses PET and MRI brain scans to better understand brain changes in multiple sclerosis, Alzheimer’s disease, and other neurological or mood conditions. The goal is to test whether these scans can show disease-related differences and guide future treatments.
Boston, MassachusettsAges 18–85 - NCT05752656Recruiting
Tracking outcomes after deep brain stimulation for Parkinson’s
This study follows people with Parkinson’s disease to see how their thinking, behavior, and movement change over time after deep brain stimulation. It may help doctors better understand what to expect from this treatment.
RomeAges 18 years+ - NCT07357428Recruiting
Brain-computer implant study for severe paralysis or speech loss
This study tests a brain-computer implant that might help people with severe paralysis or speech loss control a computer with their thoughts. It is for people who have trouble moving and speaking due to a progressive disease or injury.
Sacramento, CaliforniaAges 22–75 - NCT06518824Recruiting
Theta brain stimulation to boost thinking in Parkinson's
This study tests whether a special pattern of deep brain stimulation (called theta bursts) can improve thinking and memory in people with Parkinson's disease. It's for patients who already have a DBS device in their brain that is at least 3 months old.
Vancouver, British ColumbiaAges 18–80 - NCT05986643Recruiting
Brain training game to improve balance in Parkinson's
This trial tests a brain-training game designed to improve balance in people with Parkinson's disease. You may be eligible if you have mild to moderate Parkinson's, have had a fall and freezing episodes in the past year, and are not very active.
LeicesterAges Any age - NCT01581580Recruiting
Deep brain stimulation surgery for movement disorders
This study looks at whether deep brain stimulation surgery can help people with certain movement problems, chosen by a specialized team. You may be considered if medicines (or other treatments) aren’t controlling your symptoms well enough or if the condition causes major disability.
Bethesda, MarylandAges 18–99 - NCT05961748Recruiting
Brain and heart illness registry for adults in China
This study is a registry that collects health information from adults who have certain new heart and/or brain conditions. It may help researchers understand how these problems occur together and improve future care planning.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07167043Enrolling by invitation
AI assistant for reading brain CT and MRI scans
This study tests an AI system that helps doctors read brain CT and MRI scans. If you had a brain scan for possible tumors, stroke, injury, or other conditions, your data could be used to improve this tool.
BeijingAges Any age - NCT05444907Recruiting
Testing treatment response in DBS-related mania in Parkinson’s
This study is looking at people with Parkinson’s who developed mania (a high-energy mood episode) after deep brain stimulation (DBS) was turned on or its settings were changed. It may help doctors better understand why this happens and how to manage it safely.
LisbonAges 18 years+ - NCT05400499Recruiting
Deep brain stimulation study in Parkinson’s visuomotor function
This trial studies how deep brain stimulation affects hand-eye (visuomotor) coordination in people with Parkinson’s. It may help researchers understand whether the stimulation settings change movement control for daily tasks.
Cleveland, OhioAges Any age - NCT06643013Recruiting
Targeting brain blood vessels to help small vessel disease
This study tests a drug that targets a protein called TSPO to see if it can improve the function of the cells lining the small blood vessels in the brain of people with cerebral small vessel disease. It may help with mild memory or thinking problems.
LondonAges 60–90 - NCT07754721Recruiting
Diet and lifestyle program for chronic acid reflux
This study tests a comprehensive program that combines diet and lifestyle changes to help people with chronic acid reflux (heartburn, acid regurgitation, or chest pain) feel better. It looks at how these changes can improve your overall health and reduce symptoms.
Hualien City, TaiwanAges 18–79 - NCT06188793Recruiting
Virtual reality for IBD pain during hospital stay
This study tests if using virtual reality can help manage pain for people with inflammatory bowel disease (IBD) while they are in the hospital. It may offer a drug-free way to feel better.
Ann Arbor, MichiganAges 18 years+ - NCT06884722Recruiting
Brain study of social perception in Parkinson's disease
This study uses brain scans to understand how people with Parkinson's disease process social cues, like faces and emotions. It may help researchers learn more about how Parkinson's affects social thinking.
BronAges 30–75 - NCT02685969Recruiting
Brain scan study of amyloid and brain sugar use
This study uses brain imaging to measure two things in the brain—amyloid protein and how the brain uses sugar. It may help researchers better understand early brain changes in people in the ALFA project.
Barcelona, CataloniaAges 45–75 - NCT07031687Recruiting
A new brain stimulation study for early Alzheimer's
This study tests a non-invasive brain stimulation method (temporal interference stimulation) to see if it can improve memory in people with early signs of Alzheimer's disease. It aims to understand how the stimulation affects brain function.
Sanya, HainanAges 60–80 - NCT06819020Enrolling by invitation
Adaptive deep brain stimulation for freezing of gait in Parkinson's
This trial tests an adaptive deep brain stimulation (DBS) system designed to improve freezing of gait in Parkinson’s disease. It is for people who still have trouble walking despite medications and are already planning to have DBS surgery.
San Francisco, CaliforniaAges 21–75 - NCT05266417RecruitingPhase 2
Nasal insulin plus glutathione for Parkinson’s symptoms
This Phase 2 study tests whether adding nasal insulin and glutathione can improve Parkinson’s disease symptoms and function. You would use study medicine through the nose while keeping your other treatments mostly the same during the trial.
Davie, FloridaAges 30 years+
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Common questions
- Are there clinical trials for brain diseases?
- Yes. Clin2 currently lists 328 recruiting brain diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.