Clinical trials
Brain Diseases clinical trials
Below are recruiting brain diseases clinical trials, each written for real people, not researchers. We’re tracking 336 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06642519Enrolling by invitation
Brain-computer interface for freezing of gait in Parkinson's
This study tests a brain-computer interface device to help people with Parkinson's disease who experience freezing of gait. The goal is to see if the device can reduce freezing episodes when medication isn't enough.
Toronto, OntarioAges Any age - NCT07110376Recruiting
Brain recordings during sleep with deep brain stimulation for Parkinson's
This study looks at brain activity during sleep in people with Parkinson's who have a deep brain stimulation (DBS) device. It aims to understand how different DBS settings affect sleep, which may help improve treatment.
Cleveland, OhioAges 18 years+ - NCT06835283Recruiting
Brain stimulation for mood and behavior in Alzheimer's
This study tests a non-invasive brain stimulation treatment designed to help with difficult mood and behavior symptoms in people with Alzheimer's disease. If you are a veteran with mild to moderate Alzheimer's and have troubling symptoms like agitation, the treatment may help improve your quality of life.
Houston, TexasAges 65–85 - NCT04383808Recruiting
PET/MRI scan with a small injected tracer
This study tests a new brain PET “insert” that can work at the same time as MRI to create brain images. If you’re healthy and can receive an approved injected tracer (FDG or Neuraceq), you may be able to help confirm the device works safely and clearly.
Palo Alto, CaliforniaAges 21 years+ - NCT05819008Recruiting
Online brain testing for people with neurological conditions
This trial studies how well a remote, online memory and thinking assessment works for people with neurological disorders or injuries. You may be invited if you can do the computer-based testing and speak Swedish.
UmeåAges 18 years+ - NCT03992625Recruiting
Deep brain stimulation study for Parkinson’s, tremor, or dystonia
This trial studies outcomes after deep brain stimulation (a treatment that uses implanted electrodes) for people with Parkinson’s disease, essential tremor, or dystonia. It may help doctors understand who benefits most and how outcomes change after treatment.
St Louis, MissouriAges Any age - NCT06092125Recruiting
Brain disease imaging study with PET/MR scans
This trial uses advanced PET and MR scans to better understand and diagnose brain diseases like Alzheimer's, Parkinson's, epilepsy, and brain tumors. It may help identify new ways to track these conditions.
Beijing, Beijing MunicipalityAges 18–60 - NCT07365696Recruiting
Fatigue and brain fog after stem cell transplant
This trial looks at the causes of fatigue and cognitive problems (like memory or concentration issues) after a stem cell transplant. It uses old PET scans to study possible damage in the brain.
StockholmAges 20–75 - NCT06072079Enrolling by invitation
Structural chromosome changes and brain disorders
This trial is for people who have or might have a rare disease or a change in their chromosomes. The study aims to learn more about how these changes relate to brain disorders.
StockholmAges Any age - NCT05222620RecruitingPhase 2
SRS methods for untreated brain metastases under 4 cm
This trial compares two stereotactic radiation strategies for patients who have intact (not previously radiated) brain metastases that are limited in size. It aims to see which approach works best in controlling the cancer while reducing side effects.
Scottsdale, ArizonaAges 18 years+ - NCT06378515Recruiting
Physical activity, sleep, and brain health in students
This study looks at how physical activity and sleep affect your brain health, especially the glymphatic system — a system that helps clear waste from your brain. It is for university students and could help you understand how your daily habits influence your brain.
ValenciaAges 18–40 - NCT06626308Recruiting
Early signs in Huntington’s gene carriers study
This study looks for early changes in the body and brain of people who carry the Huntington’s disease gene but don’t yet have symptoms. It may help find better ways to track the disease early.
GrenobleAges 18–70 - NCT05893186RecruitingEarly Phase 1
Testing DBS settings for walking and balance in Parkinson’s
This early-phase study looks at whether adjusting deep brain stimulation (DBS) can improve posture, walking, and balance in people with Parkinson’s disease. If you already have DBS in place, the trial uses computer-based planning to try different DBS directions and settings to see what helps you most.
Minneapolis, MinnesotaAges 18–89 - NCT06932692Recruiting
Brain network analysis using 7-Tesla MRI in DBS patients
This study uses advanced brain imaging (7-Tesla MRI and MEG) to understand how deep brain stimulation (DBS) affects brain networks in people with Parkinson's disease or essential tremor. It helps doctors learn how DBS works so they can improve treatment in the future.
Amsterdam, North HollandAges 18 years+ - NCT05183152Recruiting
Non-invasive brain signal control for assistive devices
This study tests an assistive device that you control using signals from the brain and muscles without surgery. It may help people with movement problems communicate or operate devices using gentle, non-invasive sensing.
Austin, TexasAges 18–80 - NCT04706910RecruitingPhase 3
PET scan study to optimize imaging in several diseases
This trial improves a special PET scan (a type of brain/body imaging) using 18F-DOPA, to better show how certain conditions behave in the body. If you or your child may have one of the listed conditions, the study may help your doctors get clearer scan results.
Edmonton, AlbertaAges Any age - NCT04735458Recruiting
Brain network study for Parkinson’s or essential tremor
This study looks at how “inhibitory control” brain networks work in people with Parkinson’s disease or essential tremor. If you are eligible for surgery and can do the study tasks, your results may help researchers better understand movement disorders and guide future treatments.
Birmingham, AlabamaAges 18 years+ - NCT05473637Recruiting
Study causes of small vessel brain disease in stroke and memory issues
This trial looks at people who may have “small vessel” problems in the brain, which can cause stroke, memory trouble, walking changes, movement symptoms, or headaches. It may help researchers better understand the genetic and non-genetic causes, which could improve future diagnosis and treatment.
TaipeiAges 18 years+ - NCT04927156Recruiting
Check safety and use of Balt medical devices after treatment
This post-marketing study follows people after they receive Balt medical devices to make sure the devices are safe, work well, and are easy to use in real life. You may be considered if you can consent and your procedure matches their device-use rules.
AngersAges 2 years+ - NCT06788886Recruiting
Breathing practice for brain and mental health in cancer and other illnesses
This study tests a simple breathing practice to see if it can improve brain health and mental well-being for people with cancer, multiple sclerosis, or their caregivers. You will do light exercises and answer questionnaires, and some participants will also have an MRI brain scan.
Rochester, MinnesotaAges 18–85 - NCT02119611Recruiting
Deep brain stimulation for Parkinson’s, dystonia, or tremor
This study tests deep brain stimulation (DBS), a therapy that sends electrical signals to the brain, for movement problems like Parkinson’s disease, dystonia, and essential tremor. It may help people whose symptoms are not controlled enough with medications, or who already have a DBS device and need ongoing management.
Bethesda, MarylandAges 18–100 - NCT05453877Recruiting
Brain scan and health data study using a long-term cohort
This study uses existing health records and then collects or uses brain imaging (CT or MRI) along with basic health measurements. It may help researchers learn patterns in brain images that relate to health or disease risk in people from the Kailuan group.
Beijing, Beijing MunicipalityAges 18–90 - NCT00009243Recruiting
Understanding How Strokes Develop: A Research Study
This study follows people who have had or are at risk for stroke to understand what causes strokes and how they develop over time. By participating, you help researchers learn more about stroke prevention and treatment.
Washington D.C., District of ColumbiaAges 18–120 - NCT07380204Recruiting
Measuring Hsp90 in the brain with a PET scan
This study uses a special PET scan to measure a protein called Hsp90 in the brain. It aims to understand how Hsp90 levels differ in healthy people and those with Parkinson's, Alzheimer's, or ALS, which may lead to new treatments.
Leuven, Vlaam-BrabantAges 18–70
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Common questions
- Are there clinical trials for brain diseases?
- Yes. Clin2 currently lists 336 recruiting brain diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.