Clinical trials
Brain Diseases clinical trials
Below are recruiting brain diseases clinical trials, each written for real people, not researchers. We’re tracking 336 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03678194Recruiting
Smartphone app tool for doctors managing daily depression
This trial tests a smartphone app that helps doctors manage depression in everyday life. It may help improve how care is tracked and adjusted soon after starting antidepressant treatment.
BordeauxAges 18–65 - NCT07288385Recruiting
Virtual reality and brain stimulation for arm recovery after stroke
This study tests if using virtual reality along with mild brain stimulation can help improve arm and hand movement in people who have had a stroke. It is for those who are at least three months past their stroke and have moderate arm weakness.
RiyadhAges 18 years+ - NCT07567599Enrolling by invitation
Deep Brain Stimulation Surgery for Parkinson's Disease
This study follows people with Parkinson's disease who are having a surgical procedure called deep brain stimulation (DBS), where thin electrodes are placed in the brain to help control movement symptoms. Researchers will track how well the surgery works and how it affects daily activities.
Belo Horizonte, Minas GeraisAges Any age - NCT05322343Recruiting
Study biobank and brain health in people age 55–80
This study collects blood samples to build a biobank and learn how brain health changes with age. Some participants may also do an MRI scan to better understand brain changes and immune response.
Bordeaux, BordeauxAges 55–80 - NCT03671889Recruiting
Ultrasound treatment to open the brain barrier for Alzheimer’s
This trial tests a non-surgical ultrasound procedure (called MR-guided focused ultrasound) meant to temporarily “open” the brain’s protective barrier so treatments may work better for Alzheimer’s disease. It also looks at safety and how well people tolerate the procedure and related tests.
Delray Beach, FloridaAges 50–85 - NCT04406818Recruiting
MRI study of heart and brain reserve in children
This study uses MRI scans to compare how the body’s blood-flow “reserves” work in children with sickle cell anemia versus healthy children. It may help doctors understand why some children are at higher risk for blood vessel problems.
St Louis, MissouriAges 4–21 - NCT05557864Recruiting
Brain scan study for Parkinson’s patients with deep brain stimulators
This study looks at how the location of a deep brain stimulator in Parkinson’s disease affects movement problems. It mainly uses advanced 7T brain imaging to compare brain activity and motor symptoms.
Minneapolis, MinnesotaAges 21–89 - NCT07094438RecruitingPhase 1
Brain stimulation and neck surgery for severe Alzheimer's
This early-stage trial tests combining deep brain stimulation (a device that sends electrical pulses to the brain) with a neck surgery that aims to improve brain fluid drainage. It's for people with severe Alzheimer's who can still walk and do not have other major health issues.
BeijingAges 40–80 - NCT05550714Recruiting
Choosing anesthesia type during deep brain stimulation for Parkinson’s
This study compares different anesthesia choices during deep brain stimulation surgery for Parkinson’s disease, using a technique that guides electrode placement. It may help your care team choose the safest and most comfortable anesthesia approach for surgery.
BeijingAges 50–80 - NCT06094192Recruiting
Brain stimulation to improve memory in Alzheimer's
This study tests whether a gentle, noninvasive brain stimulation technique called tACS can help improve memory in people with Alzheimer's disease or mild cognitive impairment. It may also include healthy older adults for comparison.
Boston, MassachusettsAges 50–100 - NCT06911229Recruiting
Walking and freezing study for Parkinson's with DBS
This study looks at how the brain controls walking and freezing of gait in people with Parkinson's disease who have deep brain stimulation (DBS). It aims to help understand why freezing happens and improve treatments.
Gainesville, FloridaAges 18–80 - NCT04650932Recruiting
Study tests new stimulation settings for advanced Parkinson’s
This study looks at whether changing how deep brain stimulation (DBS) pulses are delivered can improve symptoms in people with advanced Parkinson’s disease. You may be eligible if you already have a specific Boston Scientific DBS device and have had it implanted for at least 3 months.
Sacramento, CaliforniaAges 18 years+ - NCT05348837Recruiting
Two-week sleep tracking for people with Parkinson’s
This study uses a wristband and a headband to track your sleep for two weeks. It’s meant to better understand sleep patterns in Parkinson’s, and may require temporarily changing your evening medication timing.
Aurora, ColoradoAges 18–80 - NCT07022522Recruiting
Brain stimulation frequencies for impulse control in Parkinson's
This study tests whether stimulating specific parts of the brain's subthalamic nucleus at different frequencies can improve control over unwanted movements or impulses in people with Parkinson's disease. If you are planning to have DBS surgery, this trial may help find a better way to use the device.
Beijing, Beijing MunicipalityAges 40–80 - NCT07446842Recruiting
AI model for better diagnosis of brain diseases
This study is building an artificial intelligence system to improve how doctors diagnose brain conditions using scans like MRI. If you are diagnosed with one of the listed conditions, your scans and medical information may help train the AI.
Wuhan, HubeiAges Any age - NCT03586258Recruiting
Brain scan and memory testing for people with brain injury
This study uses memory and thinking tests along with brain scans (likely MRI) to understand how different types of brain damage affect thinking. It may help doctors learn more about brain-related cognitive problems.
CaenAges 18 years+ - NCT05065450Recruiting
Testing whether brain stimulation improves memory in epilepsy
This trial looks at ways to improve memory by targeting specific deep brain areas in people with epilepsy. You may be eligible if you are already scheduled for long-term video monitoring with implanted depth electrodes in the memory-related regions (amygdala, hippocampus, and nearby areas).
St Louis, MissouriAges 18–75 - NCT02435810Recruiting
Study of infections and inflammation affecting the nervous system
This study looks at how infections or inflammation involving the brain and spinal cord work, using patient data and samples. It may help researchers better understand these illnesses and improve future care.
Bethesda, MarylandAges 2–110 - NCT00593203Enrolling by invitation
Share a brain tissue sample during surgery
This study collects a small piece of brain tissue during people’s planned brain surgery. It may help researchers learn more about brain conditions and improve future care.
Nashville, TennesseeAges Any age - NCT04806620Recruiting
Online app study for brain inflammation lifestyle data
This study uses a digital platform (app/website) to collect lifestyle and symptom information to better understand brain inflammation. You may qualify if you have certain conditions like Long COVID, migraines, autoimmune disease, inflammatory gut issues, mood disorders, or if you are a healthy comparison person.
Delafield, WisconsinAges 2 years+ - NCT07176494Recruiting
Revision of Deep Brain Stimulator in Parkinson's Disease
This study is for people with Parkinson's disease who need to have their deep brain stimulator (a device that sends electrical pulses to control movement) replaced or adjusted. The researchers want to learn the best way to do this procedure safely.
Ankara, Yenimahalle\AnkaraAges 40–85 - NCT06090682Recruiting
Brain stimulation for Parkinson's with thinking problems
This trial tests a brain stimulation technique (deep brain stimulation) to see if it can help people with Parkinson's disease who also have mild cognitive problems. The goal is to understand how stimulation affects both movement and thinking.
Tianjin, Tianjin MunicipalityAges Up to 75 years - NCT07410598Recruiting
Testing a new way to use deep brain stimulation at home
This study tests a new type of brain stimulation called patterned stimulation for people with Parkinson's who already have a deep brain stimulation (DBS) device. It aims to see if using this special stimulation at home is safe and comfortable.
Gainesville, FloridaAges 18–80 - NCT05822388Recruiting
Deep brain stimulation and memory changes in Parkinson’s
This study looks at whether deep brain stimulation (a surgical treatment for Parkinson’s disease) affects thinking and memory over time. It compares Parkinson’s participants to people without Parkinson’s to better understand what changes happen with treatment.
Charleston, South CarolinaAges 18 years+
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Common questions
- Are there clinical trials for brain diseases?
- Yes. Clin2 currently lists 336 recruiting brain diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.