Clinical trials
Brain Diseases clinical trials
Below are recruiting brain diseases clinical trials, each written for real people, not researchers. We’re tracking 336 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02071134Recruiting
Registry study for Vercise deep brain stimulation patients
This study keeps a record of people who receive the Vercise deep brain stimulation system. It helps doctors learn how the treatment is used in real-world care and how patients do over time.
Aliso Viejo, CaliforniaAges 18 years+ - NCT06298474Recruiting
BRAIN App for dementia support
This study is testing a new app (BRAIN App) designed to help people with dementia stay connected and engaged. Researchers want to see if the app can be useful for older adults who can still communicate and have not had a recent fast decline in health.
Winchester, MassachusettsAges 65 years+ - NCT05493514Recruiting
Robotic training program for walking and balance
This trial studies whether a robotic training system (called G-EO) can help people with neurological conditions improve walking and balance. It may help by testing which factors predict who benefits most, and it requires regular training sessions.
MilanAges 18 years+ - NCT07442747RecruitingPhase 2
Aerobic exercise benefits in Parkinson's with DBS
This trial tests whether aerobic exercise (like walking or biking) can improve brain function in people with Parkinson's who have a deep brain stimulation (DBS) device. It may help you learn how exercise affects your symptoms and DBS treatment.
Cleveland, OhioAges 18 years+ - NCT04116996Recruiting
Brain stimulation for severe insomnia in Parkinson’s
This trial tests whether stimulating a specific brain area (the globus pallidus) can improve severe insomnia in people who also have Parkinson’s symptoms. You might be considered if your insomnia is very difficult to control and you meet the study’s brain, sleep, and travel requirements.
Jacksonville, FloridaAges 40–80 - NCT05065151Recruiting
Studying motivation in Parkinson’s using brain stimulation recordings
This study looks at what drives motivation in people with Parkinson’s disease (or dystonia) by using recordings from an implanted brain stimulation device. It may help researchers understand brain signals behind motivation and improve future treatments.
San Francisco, CaliforniaAges 18 years+ - NCT05565443Recruiting
Ultrasound plus GCase treatment for Parkinson’s symptoms
This trial studies whether MR-guided focused ultrasound combined with an enzyme treatment called GCase can improve Parkinson’s disease. It includes people with specific Parkinson’s diagnosis and scan findings, and it may help those with certain genetic or imaging markers.
Toronto, OntarioAges 35–80 - NCT05568199Recruiting
Study of brain imaging in people with DBS for Parkinson’s
This trial is for adults with Parkinson’s who already have a deep brain stimulation (DBS) device and who can have 7‑Tesla (7T) brain imaging. The study uses the MRI pictures to help researchers learn more about Parkinson’s and how the brain changes with treatment.
Minneapolis, MinnesotaAges 21 years+ - NCT05892952Recruiting
Scottish long-term study of aging and thinking
This study follows adults aged 50 and older over time to understand how thinking and memory change. You may help researchers learn what influences healthy aging and cognitive health.
Edinburgh, LothianAges 50–120 - NCT06494358Recruiting
Blood tests to find genetic changes in brain AVM
This trial uses a blood test to look for genetic mutations in brain arteriovenous malformations (bAVMs). It may help doctors understand these lesions better and guide treatment.
ParisAges 18 years+ - NCT06690931Recruiting
Brain training with electrical stimulation and virtual reality for Parkinson's
This study tests a new type of therapy that combines brain training (neurofeedback), mild electrical stimulation to help with movement, and virtual reality exercises. It aims to improve walking and movement for people with Parkinson's disease.
Schiedlberg, Upper AustriaAges 40–80 - NCT06951906RecruitingPhase 4
Brain imaging study of freezing of gait after deep brain stimulation
This trial is for people with Parkinson's disease who experience freezing of gait (feeling like your feet are stuck to the floor) and are already scheduled to have deep brain stimulation surgery. The study will use MRI brain scans to understand how the surgery helps improve walking.
Charleston, South CarolinaAges 40 years+ - NCT06984445Recruiting
Cord Blood Protein in Anemia Transfusion Study
This study measures a protein (S100B) in cord blood from babies who had or did not need a blood transfusion in the womb for hemolytic disease. It looks for possible markers of brain health.
WarsawAges 18 years+ - NCT06572332Enrolling by invitation
Brain scan study for sleep in older Chinese adults
This study uses brain scans to understand sleep problems in older Chinese adults. If you are 60+ and have trouble sleeping, you may help researchers find better ways to improve sleep.
Hong KongAges 50–90 - NCT05882344Enrolling by invitation
Deep brain stimulation for early Alzheimer’s memory problems
This trial tests whether a targeted deep brain stimulation treatment can help people with early Alzheimer’s disease symptoms and memory loss. It also involves brain imaging and a surgery/anesthesia procedure to place the stimulator.
Nashville, TennesseeAges 60–80 - NCT07256704Recruiting
Hypnosis and Attention in Brain Conditions
This study tests whether hypnosis can help improve attention and focus in people with stroke, traumatic brain injury, or multiple sclerosis. It involves an EEG (a test that records brain activity) to see how the brain responds.
LucerneAges 18 years+ - NCT04124029Recruiting
Study how mild brain injuries may relate to dementia
This study looks at how past mild traumatic brain injury may contribute to brain changes seen in chronic traumatic encephalopathy (CTE) and Alzheimer’s disease (AD). It may help researchers understand risk and brain markers by comparing people with mild or moderate TBI, people with mild memory problems, and healthy controls.
Boston, MassachusettsAges 30–90 - NCT06134219Recruiting
Course for brain fatigue after Graves' disease
This study tests a course designed to help with brain fatigue (mental tiredness) that can happen after Graves' disease. It is for people whose thyroid levels are stable but who still struggle with fatigue.
GothenburgAges 18–72 - NCT07635823Recruiting
Adaptive deep brain stimulation for Parkinson's disease
This study tests a new type of deep brain stimulation (DBS)—a surgical treatment that uses electrical pulses to help control Parkinson's symptoms. Unlike standard DBS, this system adapts automatically to your body's needs. You may qualify if you've never had DBS surgery or if you've had it before and are willing to switch to the new device.
Hefei, AnhuiAges 18 years+ - NCT06685510Enrolling by invitation
Deep brain stimulation outcomes and electrode position in Parkinson's
This study looks at how the placement of electrodes during deep brain stimulation (DBS) for Parkinson's disease affects recovery and motor symptoms right after surgery. It could help doctors improve DBS outcomes for people with Parkinson's.
Nanchang, JiangxiAges 18–75 - NCT06960096Recruiting
Cognitive decline after deep brain stimulation: an MRI study
This study uses MRI scans to see how deep brain stimulation (DBS) affects thinking and memory in people with Parkinson's disease. It may help researchers understand why some people experience cognitive changes after DBS surgery.
Charleston, South CarolinaAges 18 years+ - NCT07392723RecruitingPhase 2
Flaxseed nutrition to protect memory in APOE4 adults
This study tests a special flaxseed-based nutrition drink to see if it can slow memory loss in older adults who have the APOE4 gene and mild cognitive impairment (early memory trouble). If you qualify, you'll take the drink daily for a year and have memory tests and brain scans.
New Brunswick, New JerseyAges 60 years+ - NCT07659964Recruiting
Rhythmic music and walking study for Alzheimer's
This study tests whether listening to a steady beat (rhythmic music) while walking can improve movement and brain function in people with mild Alzheimer's disease. Healthy volunteers are also needed for comparison.
Boston, MassachusettsAges 50–90 - NCT02795052Recruiting
Stem cell treatment trial for nerve injury
This study tests whether bone-marrow stem cells can improve nerve function in people with nerve damage that usually doesn’t recover with current care. It also checks whether the treatment is safe and whether people can be followed over time with repeated nerve exams.
Westport, ConnecticutAges 18 years+
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Common questions
- Are there clinical trials for brain diseases?
- Yes. Clin2 currently lists 336 recruiting brain diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.