Clinical trials
Brain Structure clinical trials
Below are recruiting brain structure clinical trials, each written for real people, not researchers. We’re tracking 25 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06556043Recruiting
Brain stimulation to improve ankle control in adults with and without stroke
This study uses mild brain stimulation (tDCS) to see if it can help middle-aged and older adults—both healthy and those who have had a stroke—learn ankle movements better. It tests whether stimulating different brain regions can improve motor skills and brain connections.
TaipeiAges 40–80 - NCT06573658Recruiting
Brain changes after balance training in older adults
This study looks at how the brain changes after balance exercises that challenge your stability. It may help find better ways to prevent falls in older adults.
Hong KongAges 60 years+ - NCT07617168Recruiting
Education Support for First-Time Brain Tumor Surgery Patients
This study tests whether education and support for patients having their first brain tumor surgery—and their caregivers—helps them cope better and recover more smoothly. You and your caregiver would receive educational materials and support throughout your treatment journey.
Istanbul, IstanbulAges 18 years+ - NCT05912270Recruiting
Music lessons to boost thinking skills in primary school
This trial studies whether an “orchestra in class” music program can improve kids’ thinking and brain development. It’s meant for younger primary school children and may help with skills like planning and attention.
GenevaAges 6–8 - NCT04076449Recruiting
MRI measurements for epilepsy from a single brain blood vessel lump
This study uses special MRI scans to measure brain changes in people whose seizures are related to one cerebral cavernous malformation (a type of abnormal blood vessel in the brain). It aims to find a measurable “biomarker” from MRI that may help understand the epilepsy and the brain structure around it.
Beijing, Beijing MunicipalityAges 18–70 - NCT07560904Recruiting
Brain Stimulation to Improve Memory in Cognitive Decline
This study tests a non-invasive brain stimulation technique to help improve working memory (the ability to hold and use information briefly) in people with mild cognitive impairment related to Parkinson's disease or Lewy body disease. The stimulation targets deep brain structures without surgery.
BrnoAges 60–80 - NCT06617377Recruiting
Can MRI predict brain recovery after cardiac arrest?
This study uses brain scans (MRI) to try to predict whether people who are still unconscious after a cardiac arrest will recover. It is looking for adults who are in a coma and have not woken up after being taken off sedation medicines for at least three days.
ToulouseAges 18 years+ - NCT05277558Recruiting
MRI and brain testing in teens at risk for type 2 diabetes
This study looks at brain health in teens with normal weight, overweight, or obesity who are at risk for type 2 diabetes. It may help researchers understand how weight and diabetes risk affect the brain, using MRI scans and learning/memory tests.
St Louis, MissouriAges 12–17 - NCT04856410Enrolling by invitation
Spaceflight cognitive testing using MRI brain scans
This study looks at how long-duration space travel affects thinking skills, especially memory and spatial navigation, and what changes happen in the brain. It compares astronauts with healthy volunteer “astronaut surrogates” and uses MRI scans to measure brain function.
Philadelphia, PennsylvaniaAges Any age - NCT05854433Enrolling by invitation
Study brain structure in adults with muscle weakness
This study uses scans and other tests to understand how brain structure relates to symptoms in people with myotonic dystrophy type 1 or type 2. It may help researchers connect measurable brain changes to movement and other clinical outcomes.
Winston-Salem, North CarolinaAges 30–65 - NCT06837857RecruitingPhase 2
Opioid pain relief study for older adults with chronic pain
This study tests whether a carefully managed prescription opioid can safely help older adults with long-term pain that hasn't been relieved by other pain medicines. The goal is to see if it improves pain without harming memory or brain health.
Rochester, MinnesotaAges 65 years+ - NCT07434037Recruiting
Trust and the brain in Down syndrome and Fragile X
This study explores how people with Down syndrome or Fragile X syndrome learn to trust others. It uses simple tasks and a brain scan (MRI) to compare their responses with those of typically developing children and young adults.
BronAges 3–29 - NCT07469566Recruiting
Studying the natural course of 7q11.23 microduplication syndrome
This study follows people with a rare genetic condition called 7q11.23 microduplication over time to understand how it affects development, learning, and health. Participants will have interviews, thinking and memory tests, and an MRI brain scan.
BronAges 5–50 - NCT07762118Recruiting
Brain stimulation with language learning for adults
This study tests whether combining a gentle brain stimulation technique with structured language-learning sessions can help adults improve their language skills. It might be an option if you are interested in boosting your language learning.
Boston, MassachusettsAges 18 years+ - NCT07762365Recruiting
Brain stimulation with reading help for children with dyslexia
This study tests whether pairing a gentle brain stimulation technique with structured reading instruction can improve reading skills in children with dyslexia. It aims to find a new way to support reading development.
Boston, MassachusettsAges 7–17 - NCT06072079Enrolling by invitation
Structural chromosome changes and brain disorders
This trial is for people who have or might have a rare disease or a change in their chromosomes. The study aims to learn more about how these changes relate to brain disorders.
StockholmAges Any age - NCT03268824Recruiting
Brain imaging study in drug-resistant focal epilepsy
This study uses MRI brain scans to see how “epileptic discharges” may affect brain connections in the developing brain. It also scans comparison participants without drug-resistant focal epilepsy to help researchers understand what is different.
ParisAges 1.5 years–16 years - NCT06826287Recruiting
7T MRI study of action watching in cerebral palsy
This study uses a very powerful 7T MRI scanner to look at how your brain responds when you watch actions. It may help doctors understand brain injury in people with cerebral palsy.
Calambrone, PISAAges 11–40 - NCT07033923Recruiting
Brain study of mood changes in depression and bipolar disorder
This study uses a mobile app and brain scans to understand day-to-day mood changes in people with depression or bipolar disorder. It may help doctors learn how to better predict and treat these conditions.
Paris, ParisAges 18 years+ - NCT07703722RecruitingPhase 3
Psilocybin and therapy for depression with trauma
This trial tests psilocybin (a compound from certain mushrooms) combined with a structured therapy to see if it helps people with depression linked to trauma. It focuses on how the treatment affects the connection between the gut and brain.
Islamabad, CapitalAges 18–60 - NCT06001073Recruiting
Heart and brain disease health prediction study
This study uses advanced health data to predict how heart and brain conditions may progress. It aims to help doctors provide better care for people with these diseases.
Xi'an, ShaanxiAges 3–80 - NCT06797661Recruiting
Brain lesion blood flow study before surgery
This study looks at how blood flow in the brain changes when there is a mass that can be removed with surgery. You would join before any treatment, which helps doctors understand the link between the brain lesion and blood vessel function.
BrusselsAges 18–90 - NCT07202494Recruiting
Brain aging and resilience MRI study
This study uses powerful MRI scans to understand how the brain ages and why some people stay healthy while others develop neurological diseases like multiple sclerosis or Alzheimer's. It compares healthy volunteers to people with certain conditions, and all participants get a detailed brain MRI.
MarseilleAges 18–90 - NCT04758624Recruiting
Study brain changes after deep brain stimulation for tremor
This study looks at how brain “wiring” (connectivity) and brain function change over time in people with essential tremor after successful deep brain stimulation. You might benefit by helping researchers better understand what DBS does in the brain, which can improve care for others with tremor.
Manhasset, New YorkAges 18–85
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Common questions
- Are there clinical trials for brain structure?
- Yes. Clin2 currently lists 25 recruiting brain structure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain structure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain structure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.