Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,059 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07288437Recruiting
Deep brain stimulation for SCA6 ataxia
This study tests if deep brain stimulation (putting a device in the brain to send mild electrical pulses) can improve balance and movement in people with spinocerebellar ataxia type 6 (SCA6), a genetic condition that causes trouble walking and coordination.
San Francisco, CaliforniaAges 21–89 - NCT04938362Recruiting
Study brain recovery after abscess using memory and brain scans
This study looks at how thinking and energy levels change after a brain abscess. It may help researchers understand what affects recovery and fatigue, using thinking tests and brain imaging/brain-wave checks.
OsloAges 16 years+ - NCT04945213RecruitingPhase 3
Biperiden to prevent seizures after traumatic brain injury
This trial tests whether biperiden can lower the chance of developing epilepsy after an acute traumatic brain injury (with bleeding or bruising seen on CT). If you qualify, you would get the medicine or a placebo soon after the injury, and researchers will compare outcomes.
Fortaleza, CearáAges 18–75 - NCT04962672Recruiting
Tested anesthesia approach for survival in high-grade brain tumors
This study checks whether a specific anesthesia plan used during surgery is practical and safe for people having their first operation for a high-grade brain tumor. If it works well, it may help support better outcomes after surgery.
Toronto, OntarioAges 18 years+ - NCT04988009Recruiting
Telemedicine care experience survey for brain tumor patients
This trial asks brain tumor patients and caregivers to share what they think about the quality of care they receive through telemedicine. Your feedback may help improve how neuro-oncology visits are done by video in the future.
Houston, TexasAges 18 years+ - NCT04995068Recruiting
Predicting Brain Lesion Risk After Mild Head Injury
This trial studies how to predict who may develop small brain injuries seen on CT scans after a mild traumatic brain injury. It may help doctors decide who needs closer monitoring or follow-up imaging.
StockholmAges 15 years+ - NCT05022940Recruiting
Track recovery and participation after adult brain injury rehab
This study follows adults with traumatic brain injury (TBI) during and after rehabilitation, to better understand how recovery and daily participation change over time. It may help improve rehab programs for people like you in the future.
Montreal, QuebecAges 17 years+ - NCT05033691Recruiting
Osimertinib plus early brain radiation versus osimertinib alone
This trial tests whether starting focused radiation to brain spots early (called SRS) along with osimertinib works better than taking osimertinib alone. It is for people with lung cancer that has an EGFR mutation and has not yet caused major brain symptoms.
JerusalemAges 18–120 - NCT05038462Recruiting
Fetal care study for babies with slow growth
This study looks at therapies meant to support brain development in babies whose growth is slower than expected before birth. It enrolls pregnancies in a specific time window and uses ultrasound/Doppler testing to make sure the baby is not likely needing delivery immediately.
BarcelonaAges 18 years+ - NCT05040542Recruiting
Brain scans of social emotions in infants
This study uses brain testing (including MRI scanning) to better understand how young children’s brains support social emotions and communication. It may help researchers learn what brain patterns look like in typical early development.
Xiamen, FujianAges Up to 6 years - NCT05045950RecruitingPhase 2
Whole brain radiation that aims to protect thinking skills
This Phase 2 trial tests a modified form of whole brain radiation to see if it can better protect thinking and memory in adults with brain metastases. You may join even if you’ve had other cancer treatments before, as long as your situation fits the study rules.
Milwaukee, WisconsinAges 18 years+ - NCT05048212RecruitingPhase 2
Nivolumab, ipilimumab, and cabozantinib for kidney cancer brain spread
This Phase 2 study tests how well nivolumab plus ipilimumab, along with cabozantinib, treats untreated or worsening kidney cancer that has spread to the brain. It may help shrink brain tumors and slow the disease when standard local brain treatments aren’t the right option.
Houston, TexasAges 18 years+ - NCT05049148Recruiting
Study platelets in brain and spinal tumors
This study looks at how blood “platelets” may be involved in brain or spinal (medullary) tumors by testing tumor tissue taken during surgery or biopsy. It may help researchers understand disease biology and guide future treatments.
ParisAges 18 years+ - NCT05064280RecruitingPhase 2
Pembrolizumab plus lenvatinib for brain metastases from solid tumors
This Phase 2 trial studies whether combining pembrolizumab with lenvatinib can shrink or control brain metastases in people with triple-negative breast cancer, lung cancer, or other solid tumors. It focuses on patients who have measurable brain lesions that can be followed on MRI.
Houston, TexasAges 18 years+ - NCT05065450Recruiting
Testing whether brain stimulation improves memory in epilepsy
This trial looks at ways to improve memory by targeting specific deep brain areas in people with epilepsy. You may be eligible if you are already scheduled for long-term video monitoring with implanted depth electrodes in the memory-related regions (amygdala, hippocampus, and nearby areas).
St Louis, MissouriAges 18–75 - NCT05084352Recruiting
Monitoring vital signs to predict recovery after head injury
This study checks vital signs (like heart rate and breathing) in the first hours after a traumatic brain injury to predict whether neurological function may decline. It may help doctors spot patients at higher risk sooner and adjust care earlier.
Baltimore, MarylandAges 18–79 - NCT05095857RecruitingPhase 4
Ketamine to improve care in severe acute brain injury
This Phase 4 trial tests whether giving ketamine during anesthesia is safe and helpful for adults with severe sudden brain injuries after surgery. It may improve how patients are sedated and cared for while they are on a breathing machine.
CopenhagenAges 18 years+ - NCT05097261RecruitingPhase 4
Ketamine for adults with severe brain injury in the ICU
This trial studies whether ketamine can improve outcomes for adults with severe traumatic brain injury when they are in the ICU and need sedation. It focuses on patients who have pressure monitoring inside the brain soon after admission.
BonheidenAges 18 years+ - NCT05100771Recruiting
MRI study for kids with focal epilepsy
This trial studies how to make MRI images better for children with epilepsy that starts in one area of the brain. It may help doctors use brain MRI more effectively when evaluating where seizures begin.
AngersAges 1–18 - NCT05102747Recruiting
Surgery-like brain radiation for up to 5 metastases
This trial compares two ways of giving focused radiation to the brain for people with a limited number of brain metastases. It aims to see which schedule works best (and is likely best for costs and quality of life).
BordeauxAges 18 years+ - NCT05106296RecruitingPhase 1
Chemo-immunotherapy with ibrutinib and indoximod for pediatric brain tumors
This Phase 1 study tests a combination treatment (ibrutinib plus indoximod along with chemotherapy) for children with brain tumors that have come back or are hard to treat. It may help shrink active tumor or control the disease when standard treatments can’t cure it.
Augusta, GeorgiaAges 3–25 - NCT05124912Recruiting
Laser treatment for recurrent brain metastases after prior SRS
This study tests whether repeating treatment with a laser (along with a small biopsy) can control brain metastases that have come back after earlier radiation called SRS. It may help people whose cancer is stable enough for surgery and who have a specific, reachable brain spot to target.
Los Angeles, CaliforniaAges 18 years+ - NCT05124236Recruiting
Pre-surgery vs post-surgery focused radiation for brain metastases
This trial compares two ways of giving focused radiation for brain metastases: before surgery or after surgery. It aims to see which timing works better to control tumors while keeping you safe.
InnsbruckAges 18 years+ - NCT05150093Recruiting
Deep brain stimulation for voice tremor or dystonia
This trial studies deep brain stimulation (a surgically placed device that sends electrical signals) to reduce voice tremor or laryngeal dystonia. You may be considered if your symptoms are persistent despite medication and you can complete the study tasks and pre-surgery testing.
Boston, MassachusettsAges 18–80
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,059 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.