Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,059 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05205174Recruiting
Check a scalp sensor to detect brain swelling after injury
This study tests whether a sensor on the scalp can detect a wave of abnormal electrical activity in the brain after a traumatic brain injury (TBI). The goal is to help clinicians monitor and possibly treat dangerous pressure build-up in the brain.
Minneapolis, MinnesotaAges Any age - NCT05222620RecruitingPhase 2
SRS methods for untreated brain metastases under 4 cm
This trial compares two stereotactic radiation strategies for patients who have intact (not previously radiated) brain metastases that are limited in size. It aims to see which approach works best in controlling the cancer while reducing side effects.
Scottsdale, ArizonaAges 18 years+ - NCT05230758RecruitingPhase 3
Metformin trial for brain tumor survivors’ brain and behavior
This Phase 3 study tests whether metformin can improve brain function, behavior, and thinking in children and teens who were treated for certain brain tumors. You may be able to join if you meet age, time-since-treatment, language, and health/lab safety requirements.
New Lambton Heights, New South WalesAges 7–21 - NCT05233475Recruiting
Rehab program after concussion in Danish adults
This trial tests a “get going” rehabilitation program for people who recently had a concussion (mild brain injury) from a head impact. It may help reduce concussion symptoms and improve day-to-day functioning in the months after injury.
Hammel, Deb´nmarkAges 18–60 - NCT05250180Recruiting
Animal-assisted therapy for kids after brain injury
This study looks at whether guided time with therapy animals helps children recover after an acquired brain injury, and what factors affect whether it works. Families may be asked to allow animal sessions and track responses over time.
Cincinnati, OhioAges 4–24 - NCT05254197Recruiting
Brain tumor monitoring study with follow-up brain scans
This study follows people with lower-grade (WHO grade 2 or less) brain tumors using repeat MRI scans over time. It helps doctors understand how these tumors change and which patients may safely delay treatment at first.
SeoulAges 18 years+ - NCT05277558Recruiting
MRI and brain testing in teens at risk for type 2 diabetes
This study looks at brain health in teens with normal weight, overweight, or obesity who are at risk for type 2 diabetes. It may help researchers understand how weight and diabetes risk affect the brain, using MRI scans and learning/memory tests.
St Louis, MissouriAges 12–17 - NCT05278715RecruitingPhase 2
New treatment plan for optic pathway glioma in children
This Phase 2 trial tests a modified chemotherapy treatment plan for children and young people with optic pathway glioma, aiming to shrink tumor and improve eye/brain symptoms. You may be able to join if your diagnosis is confirmed and your body can safely handle treatment.
BeijingAges 3 months–21 years - NCT05287750Recruiting
Brain disease study using 7.0T brain MRI scans
This study looks at people with brain conditions using a very strong MRI scanner (7.0T). It may help doctors understand brain diseases better and improve how scans are used, but you must be able to safely have the MRI (and possibly contrast dye).
BeijingAges 18–80 - NCT05303649Recruiting
Theta burst brain stimulation for language problems after stroke
This study tests whether a type of brain stimulation guided by a brain scan (MRI) can improve speech and language (“aphasia”) after a stroke. It may help people who have trouble producing speech but can still understand others’ words.
Warsaw, Masovian VoivodeshipAges 18–75 - NCT05305092Recruiting
Study of memory and thinking in early breast cancer
This study checks how breast cancer affects memory and thinking before other treatments start. It may help doctors better understand cognitive changes and who is most at risk.
Xi'an, ShaanxiAges Any age - NCT05327829RecruitingEarly Phase 1
Testing a brain-stimulation approach after concussion recovery
This early study tests whether a brain-stimulation method can help after recovery from a mild to moderate traumatic brain injury (TBI), sometimes called concussion. It also may include healthy volunteers to compare safety and computer-based brain measures.
Minneapolis, MinnesotaAges 18 years+ - NCT05331521RecruitingPhase 3
Study to improve brain function in newly diagnosed glioma patients
This Phase 3 study tests a treatment plan after surgery to improve brain function and quality of life in adults with newly diagnosed, specific types of brain tumors (gliomas). It may help you keep thinking clearly and living better while your tumor is treated with standard medicines.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT05340881Recruiting
Light exposure program for young survivors of childhood brain tumors
This trial studies whether a structured light-exposure routine can improve symptoms like fatigue and how survivors feel day to day. It is aimed at children and teens who have recovered from a non–high-risk type of brain tumor and have mild to moderate fatigue.
Houston, TexasAges 10–18 - NCT05342454Recruiting
Brain tumor surgery patients using brain scan and mapping software
This study checks a new computer software tool that helps doctors map important brain networks and how blood flow responds during brain scans. It may help improve planning and safety for people having brain tumor surgery.
Houston, TexasAges 18 years+ - NCT05346367Recruiting
Targeted brain radiation to improve treatment benefit and limit side effects
This study tests a more targeted form of stereotactic (precise) brain radiation for people with brain metastases from large cell cancer. It aims to improve the balance between effectiveness and side effects by carefully focusing where the radiation goes.
Leidschendam, South HollandAges 18 years+ - NCT05380050Recruiting
Telehealth vs in-person skills training for brain injury and PTSD
This study compares a combined skills program delivered by video/phone (telehealth) versus meeting in person. It aims to improve attention and coping skills for veterans who have both mild brain injury and PTSD.
Gainesville, FloridaAges 30–55 - NCT05402761Recruiting
Nurse-guided sleep program for insomnia after brain injury
This trial studies whether nurse-guided behavioral sleep therapy can improve insomnia in people recovering after a traumatic brain injury (TBI). It may help you sleep better by targeting sleep habits and insomnia symptoms.
TaipeiAges 20–65 - NCT05451251RecruitingPhase 1
Deep brain stimulation for severe trigeminal nerve pain
This trial tests whether deep brain stimulation can reduce intense facial pain from trigeminal neuralgia when medicines and prior procedures have not helped. You may be eligible if you’re an adult with a specific MRI finding near the trigeminal nerve pathway.
Sherbrooke, QuebecAges 18 years+ - NCT05453877Recruiting
Brain scan and health data study using a long-term cohort
This study uses existing health records and then collects or uses brain imaging (CT or MRI) along with basic health measurements. It may help researchers learn patterns in brain images that relate to health or disease risk in people from the Kailuan group.
Beijing, Beijing MunicipalityAges 18–90 - NCT05477680Recruiting
Measuring brain shift during surgery using navigation
This study tests whether a special brain-navigation method can better measure how the brain moves during surgery for certain brain conditions. If it works, it may help surgeons avoid mistakes caused by brain shifting while you are under anesthesia.
MoscowAges 18–100 - NCT05484245Recruiting
Ultrasound-guided surgery for certain brain mass lesions
This trial looks at using real-time ultrasound to help surgeons remove or treat certain brain growths and bleeding areas. It may help by making the procedure more precise for newly diagnosed cases in the upper part of the brain.
MoscowAges 18–100 - NCT05493722RecruitingEarly Phase 1
Adjusting deep brain stimulator settings for hard-to-control seizures
This early-phase study tests whether changing your deep brain stimulator settings can improve seizure control in people whose epilepsy is not helped by usual treatments. It is mainly for patients who already have the stimulator placed.
Minneapolis, MinnesotaAges 18 years+ - NCT05506085Recruiting
Brain stimulator study for voice spasms with tremor
This trial studies a brain stimulation approach for a specific voice disorder that can include tremor. It aims to better understand how well the treatment works and how to use it more effectively while carefully checking safety with awake procedures.
Indianapolis, IndianaAges 18–70
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,059 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.