Clinical trials
Breast Cancer Invasive clinical trials
Below are recruiting breast cancer invasive clinical trials, each written for real people, not researchers. We’re tracking 728 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02290834Recruiting
Studying brain and thinking changes after chemotherapy in older breast cancer patients
This study looks at how chemotherapy may affect memory and thinking, using thinking tests and possibly brain imaging. It compares older breast cancer patients who do and do not get chemotherapy, plus a group of healthy older adults.
Boston, MassachusettsAges 60 years+ - NCT07498478RecruitingPhase 2
Tinengotinib and fulvestrant for advanced HR+ HER2- breast cancer
This trial tests a new drug called tinengotinib combined with the hormone therapy fulvestrant for people with HR-positive, HER2-negative breast cancer that has come back or spread. It is for those who have already tried a CDK4/6 inhibitor and at least one hormone therapy.
Guangzhou, GuangdongAges 18 years+ - NCT06510127Enrolling by invitation
AI Predicts Chemo Effectiveness Before Breast Surgery
This study uses an AI model to predict how well chemotherapy will work before breast cancer surgery. It looks back at medical records and images from women who have already completed treatment to see if the AI can help guide future care.
Guangzhou, GuangdongAges Any age - NCT05116449Recruiting
Supportive care program for women having breast cancer surgery
This trial looks at whether getting supportive oncology care around the time of breast cancer surgery improves quality of life. You would answer questionnaires in French so the team can measure any changes over time.
Guilherand-GrangesAges 18 years+ - NCT07608848RecruitingEarly Phase 1
Imaging study of new cancer-targeting radioactive drugs
This study tests two new radioactive drugs designed to find and image advanced breast or prostate cancer. The drugs use special imaging scans (PET and SPECT) to locate tumors and may help guide future treatment decisions.
Perth, Western AustraliaAges 18 years+ - NCT06906237Recruiting
Breast reconstruction study for early-stage breast cancer
This study looks at how well special breast-conserving surgery techniques work for women with early-stage breast cancer. It aims to see if these techniques provide good results and satisfaction over time.
PadovaAges 18 years+ - NCT07123649RecruitingPhase 2
Customizing mammogram schedules for older breast cancer survivors
This study looks at how often older breast cancer survivors (80+) should get mammograms. It aims to make screening more personalized so women get the right amount of imaging.
Boston, MassachusettsAges 80 years+ - NCT06516289RecruitingPhase 2
Neoadjuvant treatment for BRCA-mutated HER2-negative breast cancer
This trial tests a combination of two oral medications (HRS-1167 and famitinib) with or without an immunotherapy drug (camrelizumab) before surgery for women with a BRCA gene mutation and HER2-negative breast cancer. It aims to see if these drugs can shrink tumors before surgery.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06185205RecruitingPhase 2
Accelerated high-dose radiation for early breast cancer
This trial tests a very short, high-dose radiation treatment given directly to the breast after lumpectomy. It aims to make radiation more convenient by finishing in just a few days instead of weeks, possibly with fewer side effects.
Richmond, VirginiaAges 45–79 - NCT07214532Recruiting
Using a blood test to guide breast cancer therapy
This study tests whether a blood test can help decide when to start additional hormone-blocking therapy for early-stage breast cancer. It aims to see if starting therapy only when the test detects cancer DNA is as effective as giving it to everyone.
Phoenix, ArizonaAges 18 years+ - NCT06910072Enrolling by invitationPhase 2/Phase 3
Chemo and immunotherapy before surgery for triple-negative breast cancer
This trial tests a combination of chemotherapy and two immunotherapy drugs given before surgery for women and men with triple-negative breast cancer. The goal is to see if this approach helps shrink or eliminate the tumor before surgery.
BeijingAges 18–75 - NCT05178498Recruiting
Diet and inflammation score in women at high breast cancer risk
This study looks at whether a person’s diet that tends to cause more body inflammation is linked to future breast cancer risk. It may help researchers understand how eating patterns could affect risk in people already considered high-risk.
Columbus, OhioAges 18 years+ - NCT07292246Recruiting
HandX-assisted endoscopic mastectomy study for breast cancer
This trial tests a new, less invasive way to remove breast tissue using a small camera (endoscope) with a device called HandX. It's for women who need a mastectomy for early-stage breast cancer, DCIS, or to reduce high risk, and aims to see if it's safe and works well.
Glyfada, AtticaAges 18 years+ - NCT05332561RecruitingPhase 2
Personalized treatment after surgery for early breast cancer
This Phase 2 study checks whether adding a personalized (biomarker-matched) medicine after standard chemotherapy and surgery lowers the risk of breast cancer coming back. Your study drug choice depends on tumor test results (from your tumor’s genetics and immune markers).
Heidelberg, Baden-WurttembergAges 18 years+ - NCT06897488RecruitingPhase 2
Omitting endocrine therapy and radiation in low-risk breast cancer
This trial tests whether older women with very low-risk, hormone-positive breast cancer can safely skip endocrine therapy (hormone-blocking pills) and radiation after lumpectomy. It aims to maintain quality of life while keeping cancer from coming back.
Houston, TexasAges 60 years+ - NCT06537960Recruiting
Later scan images to better see bladder cancer spread
This trial tests whether taking extra, later images during your standard FDG PET-CT scan can give doctors a better view of how far your muscle-invasive bladder cancer has spread. You may be eligible if you are 18 or older, have confirmed muscle-invasive bladder cancer, and are already getting this type of scan.
Suresnes, Île-de-France RegionAges 18 years+ - NCT05901428RecruitingPhase 3
Check if two breast cancer treatments work better after surgery
This trial compares two treatment approaches in people with high-risk hormone-positive, HER2-negative breast cancer that has spread to certain lymph nodes. It looks at which option works best to lower cancer returning and to control the disease after surgery and initial chemotherapy.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06693037Recruiting
Choosing next treatment after incomplete response in HER2+ breast cancer
This trial looks at the best next treatment for women with HER2-positive breast cancer who still have leftover cancer after surgery and standard pre-surgery treatment. It helps doctors choose the right therapy for you.
Beijing, Beijing MunicipalityAges Any age - NCT07402473RecruitingPhase 2
Optimizing treatment before surgery for HER2-positive breast cancer
This trial tests a neoadjuvant (before surgery) treatment plan for people with early-stage HER2-positive breast cancer. The goal is to see if a personalized approach can improve outcomes.
Elizabeth, New JerseyAges 18–90 - NCT06832904RecruitingPhase 2
Chemo plus two targeted drugs before surgery for HER2+ breast cancer
This trial tests whether giving a combination of two targeted drugs (pyrotinib and trastuzumab) along with standard chemotherapy before surgery can work better for HER2-positive breast cancer. It is for women whose cancer has not spread to distant organs and who have not yet had treatment for their cancer.
HangzhouAges 18–75 - NCT05878314Recruiting
Testing how hormones and tumor markers guide breast cancer treatment
This study looks at how planned hormone (endocrine) treatment, the menstrual cycle, and lab markers from the tumor may help doctors choose the best treatment for early-stage, hormone-receptor–positive, HER2-negative breast cancer. It may help personalize decisions, including what to do before surgery.
TübingenAges 18 years+ - NCT04344496Recruiting
Collecting breast cancer tissue to predict recurrence risk
This study builds a “genome atlas” to better predict the chance that breast cancer will come back. It asks participants to share medical information and provide blood and tumor tissue samples, including samples kept in paraffin.
TaipeiAges 20 years+ - NCT06304857RecruitingPhase 3
Protecting the heart with dapagliflozin during breast cancer treatment
This trial tests if the diabetes drug dapagliflozin can protect the heart in people with breast cancer receiving a type of chemotherapy called anthracyclines. You may be able to join if you are between 18 and 80, have stage I-III breast cancer, and are about to start anthracycline treatment within the next 60 days.
Wroclaw, Lower Silesian VoivodeshipAges 18–80 - NCT05856773RecruitingPhase 3
Standard vs shorter radiation to lymph nodes for breast cancer
This trial compares two ways of giving radiation to the breast/chest wall and nearby lymph nodes after breast surgery: a standard schedule versus a shorter “hypofractionated” schedule. It uses proton therapy and may help reduce treatment time while still controlling the cancer.
Scottsdale, ArizonaAges 19 years+
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Common questions
- Are there clinical trials for breast cancer invasive?
- Yes. Clin2 currently lists 728 recruiting breast cancer invasive studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer invasive trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer invasive trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.