Clinical trials
Breast Cancer Surgery clinical trials
Below are recruiting breast cancer surgery clinical trials, each written for real people, not researchers. We’re tracking 1,192 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06744465Recruiting
Light-based monitoring for breast cancer during chemo
This study uses a special light-based device to monitor breast cancer during chemotherapy before surgery. It is for women with HER2-positive or triple-negative breast cancer who are planning chemotherapy first.
Indianapolis, IndianaAges 18 years+ - NCT06746688RecruitingPhase 1
Safety study of ES2B-C001 for HER2-positive metastatic breast cancer
This trial tests a new drug called ES2B-C001, with or without an adjuvant, to see if it is safe for people with HER2-positive breast cancer that has spread and has not responded to previous treatments.
GrazAges 18 years+ - NCT06761196Recruiting
Quality of life after breast cancer surgery
This study looks at how breast cancer surgery affects your quality of life. It includes people with any stage of breast cancer (or at high risk) who need breast surgery under general anesthesia. The goal is to learn how to better support your recovery and well-being.
ColmarAges 18 years+ - NCT06765590Recruiting
Paclitaxel (albumin-bound) bioequivalence study in breast cancer
This study tests whether a new version of paclitaxel (albumin-bound) works the same as the approved version in people with breast cancer. It's for patients whose cancer has spread or returned after other treatments, or those for whom this drug is recommended by treatment guidelines.
Luoyang, HenanAges 18–75 - NCT06780735Recruiting
Breast-sparing surgery using a special dye after chemo
This trial tests a technique where doctors use a special dye (ICG) to guide breast-conserving surgery in patients whose tumors have shrunk enough after chemotherapy. The goal is to remove only the cancer while saving as much healthy breast tissue as possible.
Goyang-si, Gyeonggi-doAges 18 years+ - NCT06780748RecruitingPhase 2
Light-guided re-surgery for recurrent breast cancer
This trial uses a special light and dye to help surgeons find and remove lymph nodes that might contain cancer cells, in women whose breast cancer has come back in the same area after previous surgery.
Goyang-siAges 18 years+ - NCT06797635RecruitingPhase 2
Study of Patritumab Deruxtecan and Pembrolizumab for High-Risk Early Breast Cancer
This trial tests a combination of targeted therapies (patritumab deruxtecan plus pembrolizumab) along with other anticancer drugs for people with a high-risk type of early-stage breast cancer that is either triple-negative or has very low hormone receptors and is HER2-negative. The goal is to see if this approach can help prevent the cancer from coming back.
Santa Monica, CaliforniaAges 18 years+ - NCT06817954Recruiting
Breast reconstruction after mastectomy for breast cancer
This trial tests how safe and effective it is to remove the breast (mastectomy) and rebuild it right away during the same surgery. It is for women with early-stage breast cancer who want reconstruction instead of breast-sparing surgery.
Nanjing, JiangsuAges 18–75 - NCT06819215RecruitingPhase 1/Phase 2
VB15010 for advanced solid tumors with HRR gene mutation
This trial tests an oral medication (VB15010) in people with advanced solid tumors that have a specific DNA repair gene mutation (called HRR mutation). The goal is to see if the drug can stop or slow down cancer growth.
Jinan, ShandongAges 18–75 - NCT06822582Recruiting
Pelvic health rehab after breast or gynecologic cancer
This trial tests a pelvic health rehabilitation program for people who have had breast or gynecologic cancer. It aims to help with pelvic floor problems like bladder or bowel issues that can start during or after treatment.
Edmonton, AlbertaAges 18 years+ - NCT06833502RecruitingPhase 2
Screening for breast cancer spread after chemo and surgery
This trial aims to find out if doing special scans to check for breast cancer spread to organs (not just lymph nodes) is helpful in certain patients. The study looks at people with breast cancer that had already spread to lymph nodes and did not completely go away with chemotherapy and surgery.
Tampa, FloridaAges 18 years+ - NCT06835426Recruiting
Imaging removed tissue during cancer surgery
This study tests a high-resolution PET-CT scanner that takes pictures of tissue removed during surgery to help doctors see if all the cancer has been removed. You might qualify if you are having surgery for a range of cancers including breast, prostate, thyroid, skin, gastrointestinal, or brain tumors.
Ghent, Oost VlaanderenAges 18 years+ - NCT06839001RecruitingPhase 3
Freezing small breast tumors instead of surgery trial
This study tests if freezing a very small early-stage breast tumor (cryoablation) can be as effective as surgery. It may be an option for people whose tumor is small enough and hasn't spread to lymph nodes or elsewhere.
São Paulo, São PauloAges 18 years+ - NCT06858449Recruiting
Exercise and protein during chemo for breast cancer
This study tests whether adding resistance training (like lifting weights) along with a protein shake after workouts can help women with breast cancer maintain muscle and bone health while they receive chemotherapy before surgery.
Pittsburgh, PennsylvaniaAges 20–89 - NCT06860815RecruitingPhase 2
Cemiplimab with liver radiation for breast cancer that spread to the liver
This trial tests a combination of a drug called cemiplimab (an immunotherapy that helps your immune system fight cancer) and a type of targeted radiation (Y-90 SIR-Spheres) given directly to liver tumors. It is for people with breast cancer that has spread to the liver and who have already had at least one type of chemotherapy.
Duarte, CaliforniaAges 18 years+ - NCT06878547Recruiting
Ultrasound study for breast cancer tissue structure
This study uses a special ultrasound technique (VisR) to look at the structure of breast tissue and collagen in women with suspicious or known breast cancer. The goal is to see if this imaging can help doctors better understand breast cancer without needing a biopsy.
Chapel Hill, North CarolinaAges 20–90 - NCT06883201Recruiting
Blood management in breast cancer surgery
This trial tests a blood management approach for breast cancer patients with low iron or hemoglobin who are having surgery. It aims to improve recovery by treating anemia before and after surgery.
RomeAges 18 years+ - NCT06889688RecruitingPhase 3
New drug combo vs. chemo for advanced triple-negative breast cancer
This trial tests a new combination of three drugs (camrelizumab, apatinib, and eribulin) against the standard chemotherapy chosen by your doctor. It's for people with advanced triple-negative breast cancer that has gotten worse after previous treatments.
Guangzhou, GuangdongAges 18–70 - NCT06891651Recruiting
21-gene testing for older breast cancer patients with lymph node spread
This trial looks at using a 21-gene test to guide treatment decisions for women aged 65 or older who have breast cancer that has spread to lymph nodes. It aims to see if this test can help avoid unnecessary chemotherapy in this group.
Jinan, ShandongAges 65 years+ - NCT06896474Recruiting
Breast cancer treatment choice help for women 70 and older
This study tests a decision aid to help women 70 and older with early stage breast cancer choose their treatment. It looks at whether the tool helps patients and their doctors make a confident treatment choice.
Los Angeles, CaliforniaAges 18 years+ - NCT06902051Recruiting
Side-lying position for left breast cancer radiation
This trial tests whether lying on your right side during radiation therapy for left breast cancer can reduce side effects. It is for women who have had surgery for newly diagnosed left breast cancer and need radiation.
Guangzhou, Guangdong ProvinseAges 18–70 - NCT06902311RecruitingPhase 2
Shorter radiation after lumpectomy for early breast cancer
This trial tests a shorter, more intense course of daily radiation therapy (called ultra hypo-fractionation) given after lumpectomy for early-stage breast cancer. The goal is to reduce the number of treatment visits while keeping the same high level of effectiveness and safety.
Chapel Hill, North CarolinaAges 50 years+ - NCT06903468Recruiting
New cavity marking technique for breast cancer surgery and radiation
This trial tests a new way to mark the area where breast cancer is removed during lumpectomy with oncoplastic reconstruction. The goal is to make follow-up radiation more precise and reduce the need for additional surgeries.
Gainesville, FloridaAges 18 years+ - NCT06906237Recruiting
Breast reconstruction study for early-stage breast cancer
This study looks at how well special breast-conserving surgery techniques work for women with early-stage breast cancer. It aims to see if these techniques provide good results and satisfaction over time.
PadovaAges 18 years+
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Common questions
- Are there clinical trials for breast cancer surgery?
- Yes. Clin2 currently lists 1,192 recruiting breast cancer surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.