Clinical trials
Breast Cancer Surgery clinical trials
Below are recruiting breast cancer surgery clinical trials, each written for real people, not researchers. We’re tracking 1,162 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04353557Recruiting
Blood test monitoring in early-stage breast cancer
This trial uses a special blood test to track cancer signals (called ctDNA) during and after treatment for early breast cancer. It aims to see whether monitoring these signals can help guide follow-up and treatment decisions.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT06236269RecruitingPhase 2
Sacituzumab Govitecan for HR+/HER2- advanced breast cancer
This trial tests a drug called Sacituzumab Govitecan for people with HR+/HER2- advanced or metastatic breast cancer that has stopped responding to a CDK4/6 inhibitor. It looks at whether the drug can slow down the cancer and requires you to have a tumor biopsy.
Badalona, BarcelonaAges 18 years+ - NCT07798466Enrolling by invitation
Immediate breast reconstruction and radiation timing after breast cancer surgery
This trial studies whether getting radiation therapy right after breast reconstruction surgery is safe and effective for women with invasive breast cancer who had chemotherapy before surgery. It aims to improve outcomes and quality of life for patients needing both treatments.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07796880RecruitingPhase 2
Study of a new drug with hormone therapy before breast cancer surgery
This trial tests a new drug called culmerciclib when given with hormone therapy before breast cancer surgery. The goal is to see if this combination can shrink tumors and improve outcomes for patients with hormone-receptor-positive, HER2-negative breast cancer.
Guangzhou, GuangdongAges 18–70 - NCT07776613RecruitingPhase 2
Bone strengthening drug for breast cancer with osteoporosis
This study tests a new drug called romosozumab, which may help strengthen bones and reduce fractures in people with breast cancer that has spread to the bones and who also have osteoporosis. If you are on hormone therapy and have weak bones, this could help protect your bones.
Basking Ridge, New JerseyAges 18 years+ - NCT07780240Recruiting
Understanding arm band pain after breast cancer surgery
This study looks at how common axillary web syndrome (a rope-like band in the armpit after breast cancer surgery) is, who gets it, and how it affects arm function. It aims to help doctors better predict and manage this condition.
Istanbul, BAGCILARAges 18–80 - NCT07767305Recruiting
Taping vs compression for breast swelling after radiation
This study compares two non-drug treatments for breast swelling (lymphedema) that can happen after breast-conserving surgery and radiation. It tests whether special tape (Kinesio Taping) works as well as compression therapy to reduce swelling and symptoms.
Tangshan, HebeiAges 18 years+ - NCT05772390RecruitingPhase 2
Second radiation for a small breast cancer return
This Phase 2 study tests whether giving targeted radiation again to the same breast can control a small, local breast cancer that came back after prior whole-breast radiation. It may help some patients avoid or delay further treatment for the breast while carefully checking safety.
Meldola, Forlì CesenaAges 18 years+ - NCT07751783Recruiting
Exercise program for cancer survivors
This trial helps people who have finished cancer treatment start a supervised exercise routine to improve their health. It tests whether a structured program with professional guidance is safe and helpful.
Kaohsiung, TaiwanAges 18–80 - NCT07743294Recruiting
Exercise before breast cancer surgery to reduce arm swelling
This trial tests whether doing specific exercises before breast cancer surgery helps reduce arm swelling (lymphedema) after surgery, and improves quality of life and care needs. You would participate in a supervised exercise program before your surgery and then follow up after.
TaipeiAges 20 years+ - NCT07739563Recruiting
Exercise for heart health after breast cancer
This study compares two types of exercise programs for women who have completed breast cancer treatment. It aims to see which type of training helps improve heart health and fitness.
Pittsburgh, PennsylvaniaAges 20–89 - NCT07732491RecruitingPhase 2
Culmerciclib for HR+ HER2+ advanced breast cancer
This study tests a new drug called Culmerciclib for women with a certain type of advanced breast cancer that has both hormone receptors and HER2. It’s for patients whose cancer has been stable on at least 4 cycles of prior therapy.
Guangzhou, GuangdongAges 18 years+ - NCT05594095RecruitingPhase 2
Study for advanced ER+ HER2− breast cancer after CDK4/6 therapy
This Phase 2 trial tests an investigational “SNF platform” treatment for advanced ER+ (estrogen-receptor positive) and HER2− breast cancer in people who already tried CDK4/6 inhibitor therapy. It may help shrink tumors and improve outcomes for cancers that have come back or spread.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07725172Recruiting
Radiation therapy and immune function in young women with breast cancer
This trial looks at how radiation therapy affects the thymus, a gland that helps your immune system. If you are a young woman having surgery for breast cancer, you may be able to join and help researchers learn more about preserving immune health.
Durham, North CarolinaAges 18–50 - NCT05935150Recruiting
Skipping lymph node surgery in early breast cancer
This trial studies whether you can safely avoid a lymph node biopsy in the armpit for early breast cancer when scans and exams look negative. It may reduce surgery-related side effects while still keeping cancer care on track.
Nanjing, JiangsuAges 18–70 - NCT07702708Recruiting
AI predicts chemotherapy response in HR+/HER2- breast cancer
This trial uses AI to analyze your pre-treatment MRI and predict how well your tumor will respond to chemotherapy before surgery. It is for people with HR+/HER2- breast cancer who need chemo before their operation.
Fuzhou, FujianAges 18 years+ - NCT07705334RecruitingPhase 1
Study of SHY-ONC6 for advanced solid tumors
This trial tests a new drug called SHY-ONC6 that targets and breaks down cancer cells. It's for people with advanced solid tumors that haven't responded to standard treatments.
Scottsdale, ArizonaAges 18 years+ - NCT07698314Recruiting
Exercise study for women after breast cancer treatment
This study looks at how a supervised exercise program affects muscle-related substances (myokines) in women who have finished breast cancer treatment. It may help understand how exercise can support recovery.
Pittsburgh, PennsylvaniaAges 20–89 - NCT07704476Recruiting
Protein supplement after breast cancer treatment
This study tests whether taking a protein supplement plus resistance training can help improve muscle and body composition after breast cancer treatment. It could be for you if you have finished active breast cancer treatment and have been doing strength training for at least 3 months.
Pittsburgh, PennsylvaniaAges 20–89 - NCT07696637Recruiting
Mobile app for breast cancer surgery recovery
This study tests a mobile app to help people with breast cancer or a BRCA mutation who are having breast surgery with reconstruction. The app gives you information and support before and after surgery.
Vancouver, British ColumbiaAges 19 years+ - NCT04289935Recruiting
Vacuum biopsy before surgery to check treatment response
This trial studies a special vacuum-assisted biopsy taken just before breast surgery to see how well pre-surgery (neoadjuvant) chemotherapy worked. It may help doctors understand whether patients truly had a complete or near-complete response on scans, which can guide next steps.
SalzburgAges 18 years+ - NCT03788213Recruiting
Shorter vs longer radiation after breast cancer surgery
This trial compares giving breast radiation over one week versus three weeks after surgery. It aims to see whether the shorter schedule works just as well and is safe for people with certain types of early breast cancer.
Kolkata, West BengalAges 18 years+ - NCT06660628Recruiting
Radiation therapy with or without breath-hold for left breast cancer
This study compares two types of radiation therapy for left breast cancer: one using a breath-holding technique to protect the heart, and another without it. The goal is to see which is safer and more effective for women who have had surgery.
Beijing, Beijing MunicipalityAges 18–70 - NCT07686250RecruitingPhase 2
SAVI Scout for breast cancer surgery localization
This trial studies a new method (SAVI Scout) to help surgeons locate and remove breast tumors more precisely during surgery. It may reduce the need for multiple markers and improve outcomes.
Tampa, FloridaAges 18 years+
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Common questions
- Are there clinical trials for breast cancer surgery?
- Yes. Clin2 currently lists 1,162 recruiting breast cancer surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.