Clinical trials
Breast cancer clinical trials
Cancer that forms in the cells of the breast, the most common cancer in women. We’re tracking 2,414 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02012699Recruiting
Cancer registry for people with or at risk of cancer
This trial collects health information and samples (a “cancer repository”) to help researchers study cancer and cancer risk. You may be able to join if you’ve had cancer before or if you’re at higher risk or have concerning findings.
Greenwood Village, ColoradoAges 19–110 - NCT07335354Recruiting
Decision tool for breast reconstruction after mastectomy
This study is testing a decision tool to help people who are thinking about breast reconstruction surgery after a mastectomy. The tool is designed to help you and your doctor make a more informed choice.
Basking Ridge, New JerseyAges 18 years+ - NCT06930378Recruiting
Breast skin feeling after DIEP flap reconstruction
This trial compares three surgical techniques to see which one best preserves or improves skin feeling after breast reconstruction with a DIEP flap (using your own tissue to rebuild the breast). You may join if you are having this type of reconstruction and do not have nerve problems or smoke.
Geneva, Canton of GenevaAges 18–80 - NCT06836089Enrolling by invitation
MRI study for dense breasts with a special imaging technique
This trial tests whether a type of MRI called Diffusion Weighted Imaging (DWI) can more accurately identify breast issues in women with dense breast tissue. If you have dense breasts and have already had a breast MRI with DWI, this study may help improve future diagnosis.
NaplesAges 40 years+ - NCT06462963Recruiting
Single vs multiple radiation doses for cancer spread
This trial compares a single, strong dose of radiation to multiple smaller doses for treating cancer that has spread to a few spots. It aims to see which approach causes fewer side effects.
AalstAges Any age - NCT07546331Recruiting
Body Composition and Breast Reconstruction Outcomes
This study measures body composition (muscle and fat distribution) in patients undergoing breast reconstruction after mastectomy to understand how these measurements relate to surgical outcomes and recovery. Understanding these connections may help doctors better predict and optimize results for future patients.
San Francisco, CaliforniaAges 18 years+ - NCT06760507Recruiting
Family history screening for BRCA cancers in rural clinics
This trial tests a program to help women in rural public health clinics learn about their family history of BRCA-related cancers. It aims to increase genetic screening and counseling for those at higher risk.
Atlanta, GeorgiaAges 25 years+ - NCT05590949Recruiting
Bone health study for breast cancer survivors off bone medication
This study looks at bone complications in women who have finished treatment with denosumab (a bone-strengthening drug) and aromatase inhibitors (hormone therapy for breast cancer). It aims to learn more about what happens to bones after stopping these medications, which may help guide future care.
Basking Ridge, New JerseyAges 18 years+ - NCT06347926Recruiting
Light therapy for menopause symptoms in breast cancer
This study tests a light-based treatment (photobiomodulation) to see if it improves sexual quality of life for women with breast cancer who have menopause-related vaginal symptoms that the usual moisturizers did not relieve.
Montpellier, HéraultAges 18 years+ - NCT06685562Recruiting
Testing a map to help make cancer decisions together
This study tests a new way to help people with cancer and their doctors make decisions together. If you have prostate, breast, or melanoma cancer, this trial may help you understand your options better.
VejleAges 18 years+ - NCT06915168Recruiting
Nerve symptom decision aid for breast cancer patients
This study tests a decision aid tool that helps people with breast cancer and nerve-related side effects from chemotherapy (like numbness or tingling) make better choices about their treatment. If you're on your third round of taxane chemo and have these symptoms, this tool may help you talk with your doctor.
Ann Arbor, MichiganAges Any age - NCT04437160RecruitingPhase 2
Chemo after surgery for triple-negative breast cancer with leftover tumor
This Phase 2 study tests chemotherapy given after surgery for people with triple-negative breast cancer who still have cancer left after initial (neoadjuvant) chemo. It may help lower the chance the cancer comes back in people at higher risk based on leftover tumor and lymph node findings.
Beijing, Beijing MunicipalityAges 18–75 - NCT07739485RecruitingPhase 1/Phase 2
Oral paclitaxel before surgery for triple-negative breast cancer
This trial tests an oral form of a common chemo drug, paclitaxel, given before surgery for triple-negative breast cancer. It aims to find the best dose and see how well it shrinks tumors.
Guiyang, GuizhouAges 18–70 - NCT07672392Recruiting
Exercise after breast reconstruction surgery
This trial tests whether a structured exercise program after DIEP flap breast reconstruction helps improve physical fitness compared to standard care. It may help women recover strength and well-being after surgery.
Beaumont, DublinAges 18 years+ - NCT07666555RecruitingPhase 2
Culmerciclib rechallenge for HR+ HER2- breast cancer
This trial tests a new drug called Culmerciclib for women with advanced HR-positive, HER2-negative breast cancer that has stopped responding to a CDK4/6 inhibitor with hormone therapy. The goal is to see if giving this drug again can help when other treatments no longer work.
ShanghaiAges 18–75 - NCT07648914RecruitingPhase 3
BL-B01D1 versus chemotherapy for advanced hormone-receptor-positive breast cancer
This trial tests a new targeted drug called BL-B01D1 against standard chemotherapy in patients with advanced breast cancer that is hormone-receptor-positive (HR+) and HER2-negative, and has stopped responding to hormone treatments. The goal is to see if the new drug works better or has fewer side effects.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07376681Enrolling by invitation
Fertility in young breast cancer patients
This study looks at fertility, cancer outcomes, and children's health in women diagnosed with breast cancer at age 40 or younger. It aims to help you understand how breast cancer and its treatment may affect your ability to have children and your long-term health.
Taizhou, ZhejiangAges 18–40 - NCT07354022RecruitingPhase 3
Study of HRS-8080 with dalpiciclib for advanced breast cancer after hormone therapy fails
This trial tests a new combination of drugs (HRS-8080 and dalpiciclib) for women with advanced or metastatic breast cancer that has stopped responding to initial hormone therapy after surgery. It aims to see if this combination is safe and effective.
Beijing, Beijing MunicipalityAges 18–75 - NCT07263425RecruitingPhase 2
Study of thiotepa and trastuzumab for breast cancer that spread to the lining of the brain and spinal cord
This trial tests a combination of two drugs given through a special port in the head to treat HER2-positive breast cancer that has spread to the layer covering the brain and spinal cord (leptomeningeal metastasis). It aims to see if this treatment is safe and effective.
Nanjing, JiangsuAges 18–75 - NCT07034976Recruiting
Radiofrequency treatment for menopause symptoms in breast cancer survivors
This trial tests a non-surgical radiofrequency treatment, combined with pelvic floor exercises, to help with vaginal dryness and other menopause symptoms in breast cancer survivors. It may be an option if you are free of cancer and have bothersome vaginal dryness.
Madrid, MadridAges 18–75 - NCT05582538RecruitingPhase 2
Ceralasertib plus immunotherapy for advanced triple-negative breast cancer
This Phase 2 trial tests whether a drug called ceralasertib can help the immune system work better, followed by durvalumab plus nab-paclitaxel. It is for people with advanced triple-negative breast cancer whose cancer returned after earlier treatment, including chemotherapy and immune therapy.
Novara, NovaraAges 18 years+ - NCT04997993RecruitingPhase 1
Leflunomide for PTEN-altered or HER2-negative metastatic cancers
This Phase 1 trial studies whether leflunomide can slow or control advanced (metastatic) cancers in people whose tumors have specific PTEN changes or who have HER2-negative breast cancer. It’s primarily a safety-and-dosing study, but it may offer benefit if your cancer matches the tumor marker requirements.
New York, New YorkAges 18 years+ - NCT05386108RecruitingPhase 1/Phase 2
Test abemaciclib plus elacestrant for breast cancer brain spread
This trial studies whether the combination of abemaciclib and elacestrant can slow or shrink ER-positive, HER2-negative breast cancer that has spread to the brain. It is designed for people whose cancer has progressed despite prior hormone (endocrine) treatment.
Fullerton, CaliforniaAges 18 years+ - NCT04981119Recruiting
Test apheresis for CAR T manufacturing in HLA-A2 solid tumors
This trial studies how a process called apheresis is used to make CAR T cells for people with certain solid tumors. It is designed for tumors that have lost a specific immune marker (HLA-A*02), which may affect how well CAR T therapies work.
Gilbert, ArizonaAges 18 years+
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Common questions
- Are there clinical trials for breast cancer?
- Yes. Clin2 currently lists 2,414 recruiting breast cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.